Am J Transplant, Volume 16, Suppl 3 Archives - Page 172 of 180 - ATC Abstracts

2016 American Transplant Congress
Impact of Allograft Dysfunction and Early Low Grade Proteinuria on Survival in Expanded Criteria Donor Kidney Transplant Recipients.
V. López, M. Cabello, P. Ruiz, C. Jironda, D. Burgos, M. González-Molina, D. Hernández.
Nephrology, Hospital Regional de Málaga, Málaga, Spain.
Introduction. Recent studies have demonstrated a relationship between low-grade proteinuria and worse graft survival, but this has not been fully studied in expanded criteria donor…
2016 American Transplant Congress
Can We Predict New-Onset Diabetes After Transplantation Previously?
R. Imamura,¹ K. Tsutahara,² S. Nakazawa,¹ Y. Kakuta,¹ T. Abe,¹ T. Takao,² N. Ichimaru,³ S. Yamaguchi,² S. Takahara,³ N. Nonomura.¹
¹Urology, Osaka University Graduate School of Medicine, Suita, Japan; ²Urology, Osaka General Medical Center, Osaka, Japan; ³Advanced Technology for Transplantation, Osaka University Graduate School of Medicine, Suita, Japan.
Objectives: New-onset diabetes after transplantation (NODAT), one of the important complications after kidneytransplantation, leads to reduce graft survival rate and increase patient morbidity and mortality.…
2016 American Transplant Congress
Identification of Biomarkers for Progressive Fibrosis in Renal Transplant Patients Using Novel Chemical Imaging Approaches.
V. Varma,¹ A. Kajdacsy-Balla,¹ S. Akkina,² S. Setty,¹ M. Walsh.¹
¹Pathology, University of Illinois at Chicago, Chicago, IL; ²Nephrology, University of Illinois at Chicago, Chicago, IL.
BackgroundThe main treatment for end-stage renal disease is kidney transplantation, however close monitoring of post-transplant biopsies is required to identify subclinical complications. In this study,…
2016 American Transplant Congress
Myeloid-Derived Suppressor Cells (MDSC) Accumulate in Intestinal Transplant (IT) Patients.
S. Okano,¹ K. Hashimoto,¹ K. Abu-Elmagd,¹ J. Fung,¹ D. Kish,² K. Keslar,² B. Min,² R. Fairchild,² C. Miller.¹
¹Transplant Center, Cleveland Clinic, Cleveland, OH; ²Department of Immunology, Lerner Reserch Center, Cleveland Clinic, Cleveland, OH.
[Background] IT is an efficacious treatment for chronic intestinal failure. Recent advance of immunosuppressive regimens have decreased the rejection rate and improved patient survival. The…
2016 American Transplant Congress
Imaging Cell Biology In Vivo with Intravital-Microscopy.
T. Ueno,¹ M. Yeung,¹ N. Igarashi,³ T. Yokoyama,² Y. Kihara,² O. Konno,² Y. Nakamura,² H. Iwamoto,² T. Ikeda,³ M. McGrath,¹ M. Sayegh,¹ A. Chandraker.¹
¹Renal Division, Transplantation Research Center, Brigham and Women's Hospital, Boston, MA; ²Transplant Surgery, Tokyo Medical Univ., Hachioji, Tokyo, Japan; ³Intensive Care Medicine, Tokyo Medical Univ., Hachioji, Tokyo, Japan.
Background: Despite current immunosuppressive therapy, many recipients endure multiple episodes of acute rejection. The interplay between dendritic cells (DCs) and T cells plays a central…
2016 American Transplant Congress
Aging Is Critically Impacting the Efficacy of Immunosuppressants.
J. Schuitenmaker, K. Edtinger, M. Seyda, H. Uehara, M. Quante, A. ElKhal, S. Tullius.
Transplant Surgery Research Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.
Immunosenescence is broadly affecting alloimmunity with major implications on immunosuppression. Older recipients have thus far been mostly excluded from clinical trials. Here, we dissected the…
2016 American Transplant Congress
Impact of Mixed Xenogeneic Chimerism on Human B Cell Response to Pig Antigens.
H. Li, S. Shao, P. Vishwasrao, M. Holzl, M. Sykes.
Columbia Center for Translational Immunology, Columbia University, New York, NY.
Xenotransplantation is a potential solution to the organ shortage in clinical transplantation. Pigs are regarded as the most suitable donors. Studies in pig-to-nonhuman primates have…
2016 American Transplant Congress
African Americans Have Greater Odds of Late Stage Diagnosis of Hepatocellular Carcinoma in Mississippi.
M. Aru, S. Seals, B. Ingram, A. Seawright, C. Anderson, T. Earl.
Department of Surgery, University of Mississippi Medical Center, Jackson, MS.
Introduction: Centers for Disease Control Cancer Data show that death rates from HCC exceed expectations from incident rates in Mississippi, therefore we hypothesized that socioeconomic…
2016 American Transplant Congress
Dynamic Detection of Anti-HLA Antibodies Can Predict aGVHD and OS in HLA-12/12 Matched Unrelated-Donor Allo-HSCT for Hematological Malignancies.
J. He,¹ Z. Pan,¹ X. Yuan,¹ Y. Li,¹ X. Wu,² W. Zhu,² X. Bao,¹ Q. Zhao.²
¹Department of HLA Laboratory, Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China; ²Department of Hematology, Jiangsu Institute of Hematology, Key Laboratory of Thrombosis and Hemostasis of Ministry of Health, First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.
The NMDP and CIBMTR provided guidelines for the use of anti-HLA antibodies in unrelated-donors hematopoietic stem cell transplantation (HSCT). However, a deeper understanding of other…
2016 American Transplant Congress
Long Term Safety of Intravenous Ketorolac Use After Donor Nephrectomy.
P. Tabrizian,¹ M. Giacca,¹ J. Prigoff,² E. Chin,² M. Palese,² D. Herron,² A. Arvelakis,¹ D. LaPointe Rudow,¹ S. Florman,¹ R. Shapiro.¹
¹Transplant, Recanati/Miller Transplantation Institute, New York, NY; ²Surgery, Mount Sinai Medical Center, New York, NY.
Background: The benefit and short-term safety have been established in previous studies; however, the risk of bleeding and long-term renal impairment in patients undergoing donor…