ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    The Incidence, Risk Factors and Clinical Course of De Novo Hepatitis B Infection in Pediatric Living Donor Liver Transplantation.

    Z. Baris, F. Ozcay, G. Moray, M. Haberal.

    Pediatric Gastroenterology, Baskent University, Ankara, Turkey; Pediatric Gastroenterology, Baskent University, Ankara, Turkey; Department of General Surgery, Baskent University, Ankara, Turkey; Department of General Surgery, Baskent University, Ankara, Turkey.

    Aim: We evaluated the incidence, risk factors and clinical course of liver transplanted pediatric patients with de novo hepatitis B infection and the clinical course…
  • 2016 American Transplant Congress

    Identification of Donor HLA-Specific Antibodies as a Risk Factor for Graft Dysfunction and Failure Following BK Virus Associated Nephropathy.

    E. Abuhelaiqa, S. Salvatore, J. Lee, J. Lee, V. Sharma, T. Muthukumar, S. Seshan, M. Suthanthiran, D. Dadhania.

    Transplantation Medicine, Weill Cornell Medicine, New York, NY.

    Background: BK virus associated nephropathy (BKVN) has emerged as a significant cause of graft dysfunction and graft failure. Identification of risk factors for graft dysfunction…
  • 2016 American Transplant Congress

    Treatment of Post-Transplant Focal Glomerulosclerosis: The Effect on Histopathology Lesions and Podocyte Foot Process Effacement.

    K. Koutroutsos,1 J. Moss,2 L. Moran,2 T. Cook,2 R. Charif,1 D. Taube,1 C. Roufosse,2 M. Loucaidou.1

    1Renal and Transplant Centre, Imperial Healthcare NHS Trust, London, United Kingdom; 2Department of Histopathology, Imperial Healthcare NHS Trust, London, United Kingdom.

    Background: Post-transplant Focal Segmental Glomerulosclerosis (FSGS) is associated with increased risk for renal allograft failure. It has been reported in the literature that podocyte foot…
  • 2016 American Transplant Congress

    Stratifying Skin Versus Non-Skin Cancer Risk Post-Kidney Transplantation According to Patient Characteristics.

    F. Jackson-Spence,1 H. Gillott,1 S. Tahir,1 F. Evison,2 J. Nath,3 A. Sharif.3

    1University of Birmingham Medical School, Birmingham, United Kingdom; 2Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom; 3Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.

    Introduction Cancer is a significant cause of morbidity and mortality after kidney transplantation but risk differs e.g. non-melanoma skin cancers have a better prognosis compared…
  • 2016 American Transplant Congress

    Do Powerful Induction Antibodies Increase Post Renal Transplant Infections?

    M. John, I. Dortonne, B. Kim, C. Li, M. Killackey, A. Paramesh, B. Lee, R. Zhang, G. Parker, J. Buell.

    Transplant Institute, Tulane University School of Medicine, New Orleans, LA.

    Purpose: Infection is one of the most common and costly complications of solid organ transplantation. Alemtuzemab (AL) is a powerful antibody that significantly reduced rejection…
  • 2016 American Transplant Congress

    Hepatitis B Immune Globulin Withdrawal in HBsAg Positive Liver Transplant Patients.

    A. Nolan,1 C. Onwudiwe,1 A. Rangnekar,2 R. Satoskar,2 T. Fishbein.2

    1Department of Pharmacy, Medstar Georgetown University Hospital, Washington, DC; 2Medstar Georgetown Transplant Institute, Medstar Georgetown University Hospital, Washington, DC.

    Introduction: Liver transplantation for chronic hepatitis B virus (HBV) is associated with a high recurrence rate of HBV post-transplant without the use of prophylaxis. The…
  • 2016 American Transplant Congress

    Ischemia-Reperfusion Injury Following Transplantation: Implications for the Modulation of CXCL8 Chemokine Function.

    B. Martinez Burgo,1 S. Ali,1 J. Kirby,1 N. Sheerin,1 S. Cobb,2 D. Kashanin.3

    1Institute of Cellular Medicine, Newcastle University, Newcastle-upon-Tyne, United Kingdom; 2Chemistry Department, Durham University, Durham, United Kingdom; 3Cellix Ltd., Dublin, Ireland.

    Ischemia-Reperfusion Injury (IRI) is a major contributor to subsequent graft dysfunction. Chemokines play a key role in leukocyte recruitment towards to the injured tissue. CXCL8…
  • 2016 American Transplant Congress

    Elevated Urinary 11-Dehydrothromboxane B2 Is Associated with Increased Bleeding Risk in Left Ventricular Assist Device Patients.

    W. Schultz,4 A. Pekarek,3 R. Cole,1 A. Duncan,5 S. Laskar,1 A. Smith,1 D. Nguyen,2 J. Vega, D. Gupta.1

    1Division of Cardiology, Emory University School of Medicine, Atlanta, GA; 2Division of Cardiothoracic Surgery, Emory University School of Medicine, Atlanta, GA; 3Heart Transplant Services, Emory University Hospital, Atlanta, GA; 4Department of Medicine, Emory University School of Medicine, Atlanta, GA; 5Department of Pathology, Emory University School of Medicine, Atlanta, GA.

    Purpose: To understand if there is a relationship between aspirin resistance as measured by elevated levels of urinary 11-dehydrothromboxane B2 in patients supported with continuous…
  • 2016 American Transplant Congress

    Normothermic Ex-Vivo Perfusion of the Intestine: The Introduction of an Innovative Physiologic Model with Novel Biomarkers.

    B. Soliman, T. Okamoto, C. Quintini, Q. Liu, M. Fujiki, A. Khanna, K. Hashimoto, J. Fung, K. Abu-Elmagd.

    General Surgery, Transplant Center, Cleveland Clinic Foundation, Cleveland, OH.

    Purpose: Ischemia reperfusion injury is a major risk factor for short and long-term functional survival after intestinal transplantation. Normothermic machine perfusion is an emerging biotechnology…
  • 2016 American Transplant Congress

    Effects of Immunosuppression and Sun Exposure on Immune Cell Populations in Skin and Blood of Kidney Transplant Recipients.

    M. Burke,1 L. Nahum,4 N. Isbel,1 R. Carroll,3 H. Soyer,1 R. Francis,1 J. Bridge,1 C. Staatz,2 J. Wells.1

    1Translational Research Institute, Brisbane, Australia; 2University of Queensland, Brisbane, Australia; 3Royal Adelaide Hospital, Adelaide, Australia; 4Ben Gurion University of the Negev, Beersheba, Israel.

    BackgroundKidney transplant recipients (KTR) receiving sirolimus accrue fewer skin cancers than KTR receiving calcineurin inhibitor (CNI) based immunosuppression, potentially due to effects of sirolimus and…
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