Am J Transplant, Volume 16, Suppl 3 Archives - Page 147 of 180 - ATC Abstracts

2016 American Transplant Congress
Patients Treated with Belatacept Show Low Levels of APRIL and HLA Antibodies.
M. Rial,¹ N. Ambrosi,² F. Caro,² D. Curcio,¹ J. Salaberry,² O. Guardia,¹ A. Dotta,¹ D. Guerrieri,² K. Padros,³ E. Chuluyan,² D. Casadei.
¹Instituto de Nefrología, Nephrology, Buenos Aires, Argentina; ²CEFYBO, Facultad de Medicina, UBA-CONICET, Buenos Aires, Argentina; ³PRICAI, Fundación Favaloro, Buenos Aires, Argentina.
Belatacept, a fusión protein that blocks the B7-CD28 costimulation pathway, decreases the level of antibodies in non-human primates and murine models but, few studies have…
2016 American Transplant Congress
Deceased Donor Kidney Transplantation in the Setting of Positive Donor-Specific Antibodies.
B. Orandi,¹ J. Montgomery,² E. Kraus,¹ D. Segev,¹ R. Montgomery,¹ N. Alachkar.¹
¹Johns Hopkins University, Baltimore; ²University of Michigan, Ann Arbor.
Recent changes to the kidney allocation system favor highly sensitized transplant candidates, resulting in these patients receiving more offers for deceased donor (DD) kidneys. Despite…
2016 American Transplant Congress
Clinical Factors That Determine the More Appropriate Induction Agent: ATG versus IL-2 Receptor Antagonists.
S. Bae, A. Massie, S. DiBrito, X. Luo, L. Kucirka, F. Al Ammary, D. Segev.
Johns Hopkins, Baltimore, MD.
Antithymocyte globulin (ATG) is recommended over IL-2 receptor antagonist (IL2) in high-risk recipients for induction immunosuppression. However, “high-risk” status has not been defined in an…
2016 American Transplant Congress
Outcomes in Obese Renal Transplant Recipients Using High versus Low-Dose Thymoglobulin.
N. Jasiak,¹ C. Stromayer,¹ J. Thielke,¹ J. Chen,² J. Chen,¹ B. Talon,¹ R. Rubin-Tobar,¹ E. Benedetti,² P. West-Thielke.^1,2
¹Pharmacy, University of Illinois, Chicago; ²Transplant Surgery, University of Illinois, Chicago, IL.
Background: Dosing of rabbit anti-thymocyte globulin (rATG) induction in renal transplant recipients is highly variable by transplant center. Optimizing rATG dose becomes extremely important for…
2016 American Transplant Congress
Prospective Randomized Controlled Study Evaluating the Relationship Between Electronic Adherence Data and Tacrolimus Concentration Data.
B. Kane,¹ M. Lockwood,¹ L. Potter,¹ L. Lourenco,¹ A. Bodzin,¹ D. Covington,² K. Mayer,³ J. Millis.¹
¹University of Chicago Transplant Center, University of Chicago, Chicago, IL; ²Clinical Research, Innovation Clinical Research, LLC, Tucson, AZ; ³R&D, SIMpill, LLC, Madison, WI.
Purpose: The SIMpill® Medication Adherence System (MAS) is being evaluated in transplant recipients in a prospective 3-year study. The MAS captures patient medication adherence data…
2016 American Transplant Congress
Liver Graft Rejuvenation Prior to Transplantation: A Bench-to-Bedside Approach.
A. Zarrinpar,¹ B. Ke,¹ H. Ji,¹ E. Reed,² R. Busuttil,¹ J. Kupiec-Weglinski.¹
¹Surgery, Dumont-UCLA Translant Center, Los Angeles, CA; ²Pathology, UCLA, Los Angeles, CA.
To address the shortage of organs for transplantation many use “marginal” livers, which are particularly susceptible to ischemia-reperfusion injury (IRI). We have taken a two-pronged…
2016 American Transplant Congress
Ex Vivo Perfusion of Porcine Forelimbs to Prolong Allowable Ischemia Time.
N. Krezdorn,¹ M. Kueckelhaus,² A. Dermietzel,² M. Alhefzi,¹ M. Aycart,¹ S. Fischer,³ T.-S. Win,¹ H. Kiwanuka,¹ E. Bueno,¹ B. Pomahac.¹
¹Department of Surgery, Division of Plastic Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston; ²Department of Plastic Surgery, Burn Center, Sarcoma Reference Center, BG University Hospital Bergmannsheil, Bochum, Germany; ³Department of Hand, Plastic and Reconstructive Surgery, Burn Trauma Center, BG Trauma Center Ludwigshafen, Heidelberg, Germany.
PurposeSuccessful replantation in patients suffering from traumatic amputation of one or more extremities is limited by the muscle ischemia time of 4-6h, which also holds…
2016 American Transplant Congress
Signs of a Dying Organ: Beyond Resistance in Subnormothermic Kidney Perfusion.
M. Blum, D. Urcuyo, Q. Liu, B. Soliman, T. Okamoto, D. Goldfarb, C. Quintini.
Cleveland Clinic, Cleveland, OH.
Purpose: In hypothermic machine preservation of the kidney, resistance is often used to assess organ quality. Since no prognostic standard yet exists for subnormothermic ex-vivo…
2016 American Transplant Congress
Improving Donor Comfort: Perioperative Dexamethasone Decreases Nausea, Vomiting, and Pain After Laparoscopic Donor Nephrectomy.
S. Yamanaga,^1,2 A. Posselt,¹ C. Freise,¹ S.-M. Kang.¹
¹Division of Transplant Surgery, Department of Surgery, University of California-San Francisco, San Francisco, CA; ²Department of General Surgery, Japanese Red Cross Kumamoto Hospital, Kumamoto, Japan.
Introduction: Postoperative nausea and vomiting (PONV) and pain are common adverse events after laparoscopic surgery. Perioperative dexamethasone (8-10mg) has been reported to decrease PONV and…
2016 American Transplant Congress
Prospective Investigation of the Reliability and Validity of the Live Donor Assessment Tool (LDAT).
D. LaPointe Rudow, A. Shenoy, J. Hunt, Z. Filipovic-Jewell, B. Haydel, B. Iacoviello.
Recanati Miller Transplantation Institute, Mount Sinai Hospital, New York, NY.
Purpose: The LDAT was the first psychosocial assessment instrument developed to standardize the live donor (LD) psychosocial evaluation (PsychE). Previously, it was found to be…