ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Acute Rejections and Incidence of De Novo DSA Depend on Donor Factors and Deceased Donor Kidney Associated Risk Assessed by the Kidney Donor Profile Index (KDPI).

    O. Staeck, D. Khadzhynov, L. Lehner, A. Kleinsteuber, M. Duerr, E. Schrezenmeier, K. Budde, F. Halleck.

    Nephrology, Charite, Berlin, Germany.

    Introduction: Little data exist analyzing the influence of donor kidney quality on the immunologic outcome and applying the KDPI in a European cohort.Methods: This retrospective…
  • 2016 American Transplant Congress

    Outcomes of Sequential and En Bloc Transplants in the Elderly: 10 Year Review of UNOS Data.

    V. Whittaker,1 R. Gruessner,1 A. Vikram,2 A. Gruessner.

    1Surgery, SUNY Upstate Medical University, Syracuse, NY; 2Medicine, SUNY Upstate Medical University, Syracuse, NY.

    To evaluate the outcome of sequential and en bloc transplants in the elderly.Method: Retrospective review UNOS data 2004-2014 kidney transplant alone patients >65 years. Patient…
  • 2016 American Transplant Congress

    Soluble ST2 and Cardiovascular (CV) Outcomes and Mortality in Kidney Transplant Candidates.

    M. Keddis,1 Z. El-Zoghby,2 A. Gray,2 J. Meeusen,2 L. Donato,2 F. Cosio,2 D. Steidley.1

    1Mayo Clinic, Phoenix, AZ; 2Mayo Clinic, Rochester, MN.

    Introduction: Soluble ST2(sST2), involved in T-cell mediated inflammation and cardiac fibrosis, is a better predictor of cardiovascular events(CVE) in heart failure(HF) and is less affected…
  • 2016 American Transplant Congress

    Impact of Left Ventricular Diastolic Dysfunction on Patients Being Evaluated for Liver Transplantation.

    K. Forde,1 R. McLean,1 W. O'Donnell,1 K. Krok,2 M. Patel,1 G. Lin,3 J. Oh,3 M. Krowka,3 M. Fallon,4 S. Kawut.1

    1Medicine, University of Pennsylvania, Philadelphia, PA; 2Medicine, Penn State Hershey, Hershey, PA; 3Medicine, Mayo Clinic, Rochester, MN; 4Medicine, University of Texas Medical School – Houston, Houston, TX.

    IntroductionDiastolic dysfunction (DD) is the cardinal finding in cirrhotic cardiomyopathy, a condition in patients with liver disease that is associated with an increased risk of…
  • 2016 American Transplant Congress

    MELD as a Metric for Survival Benefit of Liver Transplantation.

    X. Luo, A. Massie, S. Bae, M. Bowring, D. Segev.

    JHU, Baltimore.

    MELD predicts waitlist mortality and thus, patients with higher MELD get higher priority in liver allocation. However, this disease severity based allocation system is controversial…
  • 2016 American Transplant Congress

    Systematic Review and Meta-Analysis of the Impact of Computed Tomography Assessed Skeletal Muscle Mass on Outcome in Patients Awaiting or Undergoing Liver Transplantation.

    J. van Vugt,1 S. Levolger,1 R. de Bruin,1 J. van Rosmalen,2 H. Metselaar,3 J. IJzermans.1

    1Surgery, Erasmus University Medical Center, Rotterdam, Netherlands; 2Biostatistics, Erasmus University Medical Center, Rotterdam, Netherlands; 3Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, Netherlands.

    BackgroundAlthough liver transplant outcome has improved significantly, the shortage of human organs remains prevalent. Therefore, strict patient selection is of paramount importance. Recently, low CT-assessed…
  • 2016 American Transplant Congress

    Hyponatremia in Early Post Lung Transplantation Predicts Patient and Hospital Outcomes.

    E. Tantisattamo,1 A. Chokechanachaisakul,2 O. Traitanon,3 A. Shetty,2 B. Ho,2 J. Friedewald,2 S. Bhorade,2 A. Haynes,2 A. Nieland,2 L. Gallon.2

    1Oakland University William Beaumont School of Medicine, Royal Oak, MI; 2Northwestern University Feinberg School of Medicine, Chicago, IL; 3Department of Medicine-Nephrology, Thammasart University Hospital, Pathumthani, Thailand.

    Background: Outcomes of hyponatremia during immediate post-lung transplantation are unknown. We aim to identify the incidence of postoperative hyponatremia and its outcomes.Methods: All lung transplantations…
  • 2016 American Transplant Congress

    Prospective Single Antigen Bead Epitope-Based Clustering for Early Detection of Antibody Mediated Rejection.

    A. Lichvar, S. Tremblay, P. Brailey, A. Girnita, R. Alloway, E. Woodle.

    U of Cincinnati, Cincinnati.

    Purpose:Epitope-based groups of HLA single antigen beads (SAB) often demonstrate clustering in patients with donor specific antibodies (DSA). Coordinated Mean Florescent Intensity (MFI) increases of…
  • 2016 American Transplant Congress

    Baseline Donor Specific Antibody (DSA) More Predictive of Chronic Antibody Mediated Rejection (CAMR) Than the Change in DSA Over Time.

    D. Mitema,1 W. Cheungpasitporn,1 M. Stegall,1 F. Cosio,1 M. Gandhi,2 C. Schinstock.1

    1Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN; 2Division of Transfusion Medicine, Mayo Clinic, Rochester, MN.

    Introduction: Although therapies are available to at least temporarily reduce DSA, the change in DSA naturally post-transplant remains unknown. We aim to study the serial…
  • 2016 American Transplant Congress

    Alemtuzumab Induction Therapy in Elderly Kidney Transplant Recipients.

    I. Yakubu,1 B. Masters,1 B. Ravichandran,1 T. Sparkes,1 M. Moss,1 F. Rasetto,1 S. Jonchhe,1 B. Thomas,2 N. Costa,2 D. Leeser,2 S. Bartlett,2 A. Haririan.2

    1Pharmacy, University of Maryland Medical Center, Baltimore; 2University of Maryland Medical Center, Baltimore.

    Background: In descriptive studies, alemtuzumab has been associated with an escalating risk of death and graft loss in elderly (≥65 years) kidney transplant recipients. However,…
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