Am J Transplant, Volume 16, Suppl 3 Archives - Page 111 of 180 - ATC Abstracts

2016 American Transplant Congress
Immune Response to BK Virus in Renal Transplant Recipients.
D. DeWolfe,¹ J. Gandhi,¹ M. Mackenzie,¹ T. Broge,¹ E. Bord,¹ D. Mandelbrot,¹ R. Viscidi,² F. Cardarelli,¹ M. Pavlakis,¹ C. Tan.¹
¹Medicine, Beth Israel Deaconess Medical Center, Boston, MA; ²Pediatrics, Johns Hopkins Medical Center, Baltimore, MD.
Background: The adaptive immune characteristics associated with BK Virus (BKV) infection and control remain incompletely described. In this study we further elucidate the immune response…
2016 American Transplant Congress
AT1R Antibodies at 1-Year Negatively Impact 5-Year Native Renal Function in Liver Transplant Recipients.
J. O'Leary,¹ A. Philippe,² H. Heidecke,² R. Freeman,¹ L. Jennings,¹ R. Catar,² G. Klintmalm,¹ D. Dragun.²
¹Baylor Simmons Transplant Insttute, Baylor University Medical Center, Dallas, TX; ²Internal Medicine, Charite, Berlin, Germany.
Angiotensin II Type-1 Receptor (AT1R) antibodies have been associated with pulmonary hypertension, renal allograft loss, and fibrosis progression in liver allograft recipients especially if combined…
2016 American Transplant Congress
Role of Cardiac Evaluation and Management in Kidney and Liver Transplant Candidates.
W. Bannister, C. Wu, M. Schnitzler, A. Bonagura, B. Laihinen, F. Irwin.
Complex Medical Conditions, Optum, UnitedHealth Group, Eden Prairie, MN; Surgery, St Louis University, St Louis, MO.
Cardiac evaluation and risk stratification prior to kidney and liver transplantation can be critical to patient selection and outcomes.Methods: We assessed the impact of cardiac…
2016 American Transplant Congress
Evolution of Body Composition and Associations to Glucose Metabolism During the First Year After Kidney Transplantation.
M. von Düring,¹ A. Hartmann,^1,2 J. Bollerslev,^2,4 A. Åsberg,^1,3 K. Godang,⁴ I. Eide,¹ D. Dahle,¹ T. Jenssen.^1,5
¹Department of Transplantation Medicine, Oslo University Hospital, Rikshospitalet, Oslo, Norway; ²Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway; ³School of Pharmacy, University of Oslo, Oslo, Norway; ⁴Department of Endocrinology, Oslo University Hospital, Rikshospitalet, Oslo, Norway; ⁵Metabolic and Renal Research Group, University of Tromsø, Tromsø, Norway.
Background. The evolution and association between body composition and glucose haemostasis after kidney transplantation has not been elucidated.Methods. We investigated 150 consecutive patients without suspected…
2016 American Transplant Congress
Hepatocellular Carcinoma Decreases Chance of Successful HCV Therapy in the Current Era.
S. Prenner, L. VanWagner, L. Kulik.
Gastroenterology and Hepatology, Northwestern University, Chicago, IL.
Background: The efficacy of direct acting antiviral agents (DAA) for hepatitis C (HCV) in patients with hepatocellular carcinoma (HCC) is limited. We hypothesized that virology…
2016 American Transplant Congress
Incidence & Impact of De Novo DSA (dnDSA) Formation on Transplant Outcomes in HLA-Sensitized (HS) Patients Transplanted After IVG+Rituximab Desensitization (DES).
A. Vo,¹ J. Choi,¹ J. Kahwaji,¹ J. Mirocha,² A. Peng,¹ R. Villicana,¹ S. Jordan.¹
¹Kidney Transplant, Cedars-Sinai Medical Center, LA, CA; ²Research Institute, Cedars-Sinai Medical Center, LA, CA.
Introduction: Highly-HLA sensitized patients are at risk for developing donor specific antibodies (DSA) & ABMR post-transplant (tx). However, incidence and risk of acute rejections (AR)…
2016 American Transplant Congress
Geographic Variation in Liver Supply and Demand.
J. Pyke,¹ D. Schladt,¹ J. Zeglin,¹ H. Xiong,¹ S. Gentry,^2,1 W. Kim,^3,1 J. Lake,^4,1 A. Israni.¹
¹Scientific Registry of Transplant Recipients, Minneapolis; ²United States Naval Academy, Annapolis; ³Stanford, Palo Alto; ⁴University of Minnesota, Minneapolis.
Purpose: To characterize the balance of supply and demand for deceased donor livers in the current Organ Procurement and Transplantation Network (OPTN) regions and in…
2016 American Transplant Congress
Diversity of Influenza Antibody Repertoire in Transplant Recipients with Natural Influenza Infection.
V. Ferreira, A. Chruscinski, S. Han, A. Humar, D. Kumar.
Multi-Organ Transplant, UHN, Toronto, Canada.
Background: The nature of the immune response to seasonal Influenza A Virus infection has not been well characterized in transplant patients. Antibodies may be directed…
2016 American Transplant Congress
Cytometric Deep Profiling of the CD8+ T-Cell Compartment in Transplant Patients with CMV Viremia.
V. Ferreira, D. Kumar, S. Husain, M. Bhat, P. Ashton, A. Humar.
UHN, Toronto, Canada.
Background: Cytomegalovirus (CMV) infection is a common opportunistic viral infection in transplant patients. Patterns of viremia and relapse are influenced by the host immune response,…
2016 American Transplant Congress
Intracellular OPN Is an Essential Protective Factor for Cardiac Endothelial Cell and the Long Term Heart Graft Survival.
Y. Su,^1,2,3 Z.-X. Zhang,^1,2,3 Z.-Q. Yin,¹ X.-Y. Huang,¹ A. Jevnikar.^1,2,3,4
¹Matthew Mailing Centre for Translational Transplantation Studies, Lawson Health Research Institute, London Health Sciences Centre, London Health Sciences Centre, Lodon, ON, Canada; ²Departments of Medicine, London Health Sciences Centre, Lodon, ON, Canada; ³Departments of Pathology, London Health Sciences Centre, London, ON, Canada.
[Background] Endothelial cell (EC) injury is central to cardiac allograft vasculopathy and premature graft loss. Osteopontin (OPN) is a multifunctional anti-apoptotic protein that is involved…