ATC Abstracts

American Transplant Congress abstracts

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  • 2016 American Transplant Congress

    Everolimus (EVR) versus Mycophenolate Sodium (MPS) for Recipients of Kidney Transplants from Expanded Criteria Donors (ECD) Receiving Anti-Thymocyte Globulin (r-ATG) and Tacrolimus (TAC).

    H. Tedesco-Silva,1 C. Felipe,1 A. Brigido,1 A. Bessa,1 M. Paula,1 P. Ruppel,1 M. Cristelli,1 L. Viana,1 G. Basso,1 M. Franco,2 W. Aguiar,1 J. Medina-Pestana.1

    1Nephrology Division, Hospital do Rim - UNIFESP, Sao Paulo, Brazil; 2Pathology Division, UNIFESP, Sao Paulo, Brazil.

    Introduction: There is no standard of care immunosuppressive regimen for recipients of kidneys recovered from expanded criteria donors. Several centers use r-ATG induction due to…
  • 2016 American Transplant Congress

    Crisis on the Waiting List for Children Listed in Low Volume Solid Organ Transplant Centers.

    A. Rana, E. Brewer, W. Winkelmayer, C. O'mahony, J. Goss.

    Department of Abdominal Transplantation, Baylor College of Medicine, Houston, TX.

    Purpose: In a recent analysis, we demonstrated that children listed in low volume liver transplant centers had poor waitlist survival and a depressed transplant rate…
  • 2016 American Transplant Congress

    Utilization of HCV-Positive Donors' Kidneys: Potential Benefits in the Era of Direct Acting Antiviral (DAA) Therapy.

    B. Amundsen,1 M. Sise,2 M. Lin,3 H. Deirawan,1 E. Heher,2 B. Kimball,1 J. Markmann,1 N. Elias.1

    1Massachusetts General Hospital, Boston, MA; 2Massachusetts General Hospital, Boston, MA; 3Brigham and Women's Hospital, Boston, MA.

    Organ shortage and expanding kidney waiting list fostered utilization of HCV positive donors' organs (HCVD+). HCVD+ kidneys have slightly worse long term outcomes compared with…
  • 2016 American Transplant Congress

    HO-1/SIRT1/p53 Axis Regulates Macrophage Activation and Attenuates Liver Ischemia-Reperfusion Injury in Mice.

    K. Nakamura,1 M. Zhang,2 B. Ke,1 S. Kageyama,1 R. Busuttil,1 J. Araujo,2 J. Kupiec-Weglinski.1

    1Surgery, Liver Transplant, University of California-Los Angeles, Los Angeles, CA; 2Medicine, Division of Cardiology, University of California-Los Angeles, Los Angeles, CA.

    Background/Aim: The mechanism by which macrophage heme oxygenase-1 (HO-1)-Sirtuin1 (SIRT1) signaling promotes resistance against inflammation response in liver ischemia-reperfusion injury (IRI) remains elusive. As tumor…
  • 2016 American Transplant Congress

    Thoracic Simulation Allocation Modeling (TSAM) of a 6-Tier Allocation Strategy.

    M. Colvin,1 M. Skeans,1 L. Robbins Callahan,2 L. Edwards,2 J. Zeglin,1 S. Silvestry,3 R. Davies,4 M. Farr,5 A. Israni,1 J. Rogers.6

    1SRTR, Minneapolis; 2UNOS, Richmond; 3Florida Hospital Transplant Inst, Orlando; 4Nemours/AI duPont Hosp for Children, Wilmington; 5Columbia Univ Medical Center, New York; 6Duke Univ, Durham.

    Heart allocation policy (OPTN policy 6) is in development. To stratify medical urgency, the Heart Subcommittee of the OPTN Thoracic Committee developed a 6-tier algorithm…
  • 2016 American Transplant Congress

    Risk Prediction of End-Stage Renal Disease in Living Kidney Donors.

    A. Massie, E. Chow, D. Segev.

    JHU, Baltimore.

    Recent studies have shown inreased risk of end stage renal disease (ESRD) in living kidney donors compared to healthy nondonors. Donors must understand the risk…
  • 2016 American Transplant Congress

    Long-Term Death-Censored Graft Loss in the DeKAF Study.

    A. Matas,1 A. Fieberg,1 R. Leduc,1 F. Cosio,2 R. Gaston,3 R. Mannon,3 M. Cecka,4 D. Rush,7 B. Kasiske,5 S. Gourishankar,6 J. Connett,1 J. Grande.2

    1U of MN, Mpls, MN; 2Mayo, Rochester, MN; 3UAB, Birmingham, AB; 4UCLA, LA, CA; 5HCMC, Mpls, MN; 6U Alberta, Edmonton, AB, Canada; 7UMB, Winnipeg, MB, Canada.

    The aim of the Deterioration of Kidney Allograft Function study (DeKAF) was to identify and assess the pathologies of troubled kidney grafts, that is, those…
  • 2016 American Transplant Congress

    Automated Web-Based Monitoring Identifies Significant Clinical Changes in Patients Awaiting Kidney Transplant.

    H. Braun, M. Parente, R. Hirose, G. Roll.

    Surgery, University of California-San Francisco, San Francisco, CA.

    Intro: The accuracy and integrity of very large waiting lists are difficult to maintain over time. We implemented newly available information technology to increase access…
  • 2016 American Transplant Congress

    Cognitive Impairment in Kidney Transplant Recipients.

    A. Gupta,1 D. Johnson,1 G. Chen,1 D. Subramaniam,1 T. Polshak,1 T. Thomas,1 T. Schmitt,1 D. Ladner,2 A. Yu,1 J. Burns.1

    1University of Kansas Medical Center, Kansas City, KS; 2Northwestern University, Chicago, IL.

    Background: Cognitive impairment is highly prevalent in end stage renal disease. The prevalence of cognitive impairment after kidney transplantation and the factors associated with it…
  • 2016 American Transplant Congress

    Comparison of Clinical Outcomes of Belatacept- and Tacrolimus-Based Immunosuppression in Renal Transplant Recipients.

    X. Wen,1 M. Casey,1 A. Santos,1 A. Hartzema,2 K. Womer.1

    1Department of Medicine, University of Florida, Gainesville, FL; 2Department of Pharmaceutical Outcomes and Policy, University of Florida, Gainesville, FL.

    To examine the utilization and clinical outcomes of belatacept in the real clinical setting, a retrospective cohort study was conducted using SRTR data that compared…
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