ATC Abstracts

American Transplant Congress abstracts

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  • 2020 American Transplant Congress

    Clinical Study of Standard versus Reduced Dose Tacrolimus Combined with Generic Mycophenolate Mofetil in De Novo Kidney Transplantation

    J. Bang, C. Oh

    Department of Surgery, Ajou University Medical School, Suwon, Korea, Republic of

    *Purpose: The lowering of calcineurin inhibitor exposure is possibly considered as the proper strategy to prevent calcineurin inhibitor induced nephrotoxicity in kidney transplant. This clinical…
  • 2020 American Transplant Congress

    Clinical Outcomes in Kidney Transplant Recipients Following Implementation of a Strategic Maintenance Reduction Protocol

    H. Perkins, K. Foster, N. Patel, H. Meadows, F. Bartlett, C. Perez, J. McGillicuddy, N. Pilch, M. Casey, M. A. Posadas-Salas, D. Taber

    Pharmacy, Medical University of South Carolina, Charleston, SC

    *Purpose: Post-transplant complications are commonly due to over-immunosuppression, particularly as it relates to infections. The purpose of this study was to assess clinical outcomes in…
  • 2020 American Transplant Congress

    Validation of Patient Reported Outcomes Measurement Information System (PROMIS) Computer Adaptive Testing Depression Item Bank in Kidney Transplant Recipients

    V. Shah1, A. Rezaeishahreza1, E. Lui1, R. Aser1, S. Bartlett2, M. Li1, D. Howell1, J. Peipert3, M. Novak1, I. Mucsi1

    1University Health Network, Toronto, ON, Canada, 2McGill University, Montreal, QC, Canada, 3Northwestern University, Chicago, IL

    *Purpose: To evaluate the reliability and validity of the PROMIS Depression computerized adaptive test (PROMIS-D CAT) in relation to a legacy measure in adult Kidney…
  • 2020 American Transplant Congress

    Sirolimus Combined with Low-Dose Calcineurin Inhibitor in Kidney Transplant Recipients from Expanded Criteria Donors

    J. Zhang, J. Lin, Y. Tian, W. Sun, L. Zhang

    Beijing Friendship Hospital, Capital Medical University, Beijing, China

    *Purpose: To evaluate the efficacy and safety of conversion from calcineurin inhibitor-based immunosuppressive regimen to sirolimus combined with low-dose calcineurin inhibitor in recipients with abnormal…
  • 2020 American Transplant Congress

    Tacrolimus Concentrations Are Associated with Measures of Body Composition in Adult Kidney Transplant Recipients

    K. S. Parker1, B. Derstine2, J. Sullivan2, S. Wang2, A. Mazurek1, D. Cron1, S. Waits1

    1Department of Surgery, University of Michigan, Ann Arbor, MI, 2Morphomic Analysis Group, University of Michigan, Ann Arbor, MI

    *Purpose: Tacrolimus (Tacro) is essential for kidney transplant immunosuppression but has a narrow therapeutic window. Tacro dosing preventing rejection must be balanced with potential delayed…
  • 2020 American Transplant Congress

    Impact of a De Novo Belatacept Based Immunosuppressive Regimen on Kidney Transplant Outcomes

    K. Joyal, T. Vanhove, B. Schreiber, M. Cote, S. Shao, N. Elias, H. Gilligan, K. Safa, E. Heher, W. Williams, C. Rogers

    Massachusetts General Hospital Transplant Center, Boston, MA

    *Purpose: Use of anti-thymocyte globulin (rabbit) (rATG) induction with belatacept/mycophenolate (MPA)/prednisone based immunosuppression (IS) has led to a reduction in rejection compared to that seen…
  • 2020 American Transplant Congress

    The Safety and Efficacy of 6-Month Steroid Reduction Strategy after Kidney Transplantation: A Prospective Cohort Study

    J. Bang, C. Oh, S. Lee

    Department of Surgery, Ajou University Medical School, Suwon, Korea, Republic of

    *Purpose: In kidney transplantation, immunosuppressive regimens almost always contain corticosteroids for preventing acute rejection and graft loss. However, long-term maintenance of corticosteroids has been associated…
  • 2020 American Transplant Congress

    Delayed Introduction of Mammalian Inhibitors of Rapamycin (mTOR) Post Kidney Transplantation Might Avoid the Chronic Nephrotoxicity of Calcineurin Inhibitors. Herein We Are Reporting an Eight-Years Single Center Experience of mTOR-Based Immunosuppression Regimen in Comparison with Cyclosporin-Based Regimen

    W. A. Hassan1, H. M. Tawfik2

    1Medicine-Nephrology, University of Tennessee Health Science Center, Memphis, TN, 2Medicine-Nephrology, Minia Nephrology Hospital, Minia University, Minia, Egypt

    *Purpose: Delayed introduction of mTOR inhibitors post kidney transplantation might avoid the chronic nephrotoxicity of CNI: eight-years single center experience.*Methods: This is a retrospective analysis…
  • 2020 American Transplant Congress

    The Impact of Preoperative Glucose Intolerance and Hypertension on the Living Kidney Donors

    T. Hiramitsu1, T. Tomosugi1, K. Futamura1, M. Okada1, N. Goto1, S. Narumi1, K. Uchida2, Y. Watarai1

    1Department of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya Aichi, Japan, 2Department of Transplant Surgery, Masuko Memorial Hospital, Nagoya Aichi, Japan

    *Purpose: Recently the mortality of living kidney donors was demonstrated to be significantly worse than that of healthy general population. However, the impact of preoperative…
  • 2020 American Transplant Congress

    What is the Significance of Denovo Donor Specific Antibodies in Recipients of Simultaneous Liver-Kidney Transplants?

    S. Parajuli, F. Aziz, J. Blazel, B. Muth, N. Garg, M. Mohamed, J. Rice, J. Mezrich, L. Hidalgo, D. Mandelbrot, G. Im, B. Lee

    University of Wisconsin, Madison, WI

    *Purpose: There is limited information about the utility of donor-specific HLA antibody (DSA) testing and the role of protocol kidney biopsy for de-novo donor-specific antibodies…
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