2016 American Transplant Congress
Risk of ESRD in Potential HIV+ Live Kidney Donors.
1Johns Hopkins University, Baltimore; 2University of Alabama, Birmingham.
The HOPE Act allows HIV+ individuals to be live kidney donors; however, candidacy for donation is poorly understood given the potential additional risk of ESRD…2016 American Transplant Congress
Risk Prediction of End-Stage Renal Disease in Living Kidney Donors.
Recent studies have shown inreased risk of end stage renal disease (ESRD) in living kidney donors compared to healthy nondonors. Donors must understand the risk…2016 American Transplant Congress
Are Prior Living Kidney Donors with ESRD Being Listed and Receiving Transplantation Priority in a Timely Manner?
BackgroundPrior living donors (PLDs) receive very high priority on the kidney (KI) waiting list (WL). Programs must submit requests for PLD priority to the UNOS…2016 American Transplant Congress
Circulating Angiotensin II Receptor: Possible Marker for Antibody Mediated Tissue Injury?
Transplant Surgery, VCU Health, Richmond, VA.
Background. Antibody mediated rejection is the leading cause of renal allograft failure. Membrane-bound angiotensin II receptor(AngII) in the renal allograft can be a target of…2016 American Transplant Congress
Mapping Heterogeneity in Antibody-Mediated Rejection Using Molecular Phenotypes and Archetype Analysis.
Archetype analysis is a method for identifying new relationships among samples without subdividing them into classes, finding a limited number of archetypical cases and calculating…2016 American Transplant Congress
Positive Lymphocytes Flow Cytometry Crossmatch Due to AT1r Antibodies in Absence of HLA-DSA.
The angiotensin II type 1 receptor (AT1r) plays a key role in the renin-angiotensin system. Anti-AT1R antibodies (Abs) have been associated with both acute and…2016 American Transplant Congress
Criteria for the Diagnosis of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBx).
The presence of MVI (Banff glomerulitis "g" score and Banff peritubular capillary "ptc" score) in KTxBx, often related to antibody mediated rejection (AMR), is associated…2016 American Transplant Congress
Analysis of Intra-Graft Anti-HLA Antibodies Suggests That HLA Sensitization Occurs Long After an Allograft Nephrectomy and Is Not Due to a Release of Anti-HLA Antibodies from the Failed Kidney.
Background: The mechanism leading to the appearance of anti-HLA antibodies and donor-specific antibodies (DSAs) after an allograft nephrectomy (NTx) is not fully understood. Two mechanisms…2016 American Transplant Congress
Comparison of C4d Deposition in Renal Biopsies with Luminex-Based C3d Single Antigen Bead (SAB) Detection.
Recent interest in characterizing the complement-fixing ability of post-transplant donor specific alloantibodies (DSA) resulted in the enhancement of luminex solid phase alloantibody assays to determine…2016 American Transplant Congress
Urine Cell-Free Supernatant Metabolites Diagnostic of Antibody Mediated Rejection in Kidney Allografts.
1Weill Cornell Medicine, NY; 2Weill Cornell Medical College-Qatar, Doha, Qatar.
Introduction:Urine cell-free supernatant metabolite profiles provide a unique opportunity to interrogate intra-graft processes and have distinguished acute cellular rejection from no rejection in the Clinical…
American Transplant Congress abstracts