Date: Tuesday, May 2, 2017
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall D1
Methods: A single-center retrospective analysis of medical records of 989 liver transplant recipients from 2001-2010 were reviewed and evaluated for patients who received thymo induction with delayed initiation of CNI. All patients received mycophenolate mofetil (500mg BID) and steroids (x3 months post-livert ransplant).
Results: Of 989 liver transplant recipients reviewed, 312 received thymo induction with delayed initiation of CNI. Median follow-up period was 839±629.12 (±SD) days post-liver transplant. Results are reported in Tables 1 and 2.
|Table 1||Baseline (BL)||1 Year (1yr)||Last Day of Follow-Up (FU)||1yr vs. BL||FU vs. BL|
|eGFR (mL/min/1.73 m2)||34±22.81||56±23.24||55±38.28||p<0.01||p<0.01|
|Hospital Length of Stay (days)||14±15.52|
|Thymo||# of Doses||3±1.27|
|# Days on Thymo||5±8.54|
|CNI Start Time (days)||5±2.47|
|Outcomes at FU||Deaths||12.50%|
|# Days on FU||839±629.12|
|Immunosuppressive therapy at FU||FK||60.26%|
In conclusion, in our analysis, we found that thymo induction with delayed initiation of CNI therapy in liver transplant patients is safe and associated with long-term improvements in renal function.
CITATION INFORMATION: Bajjoka I, Yaldo A, Crombez C, Brown K, Abouljoud M. Long-Term Preservation of Renal Function in Liver Transplant Recipients with Rabbit Anti-Thymocyte Globulin Induction and Delayed Initiation of Calcineurin Inhibitors. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:Bajjoka I, Yaldo A, Crombez C, Brown K, Abouljoud M. Long-Term Preservation of Renal Function in Liver Transplant Recipients with Rabbit Anti-Thymocyte Globulin Induction and Delayed Initiation of Calcineurin Inhibitors. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/long-term-preservation-of-renal-function-in-liver-transplant-recipients-with-rabbit-anti-thymocyte-globulin-induction-and-delayed-initiation-of-calcineurin-inhibitors/. Accessed April 23, 2021.
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