Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall D1
Introduction – While damage to the procured organ is rare with organ loss being approximately 0.3% of procured organs, loss of potential transplantable organs does occur during procurement. The levels of damage range from a level of “0” (no damage); level “1” (minimal damage sustained upon procurement requiring no intervention); level “2” (damage sustained upon procurement requiring some surgical repair but not rendering the allograft non-transplantable); and finally level “3” (damage sustained upon procurement rendering the allograft non-transplantable). The clinical outcomes of organs with level 2 injuries are not known.
Methodology – At Southwest Transplant Alliance, we decided to follow the deceased donor kidneys with type 2 injuries and compared them to mate non injured kidney from the same donor. We identified 16 donors with type 2 injury on one of donated kidneys. We compared graft cold ischemia time (CIT), delayed graft function, early rejection, and graft survival. Unpaired T test was used for categorical variables and Fischer exact test for continuous variables. Mean follow-up was 157 days (33-390).
Results – There was no significant difference in cold ischemia time and delayed graft function in Type 2 injury kidney group vs. mate kidney group observed with a p value of 0.372 and 0.252, respectively. Rejection rates and graft survival between these two groups were also similar.
Conclusion – Based on our case series, it appears that type 2 kidney injury had no significant impact on immediate post-transplant outcomes. More robust data and collaborative organ procurement organization research efforts are required to completely understand the impact of these injuries on outcomes.
CITATION INFORMATION: Mujtaba M, Gamilla-Crudo A, Gugliuzza K, Aleter O, Shah S, Chapman Y, Reese J, Masood S, Taber T. Impact of Type 2 Surgical Injuries in Postmortem Donor Kidneys on the Post-Transplant Outcomes When Compared to Mate Non-Injured Kidney from the Same Donor. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:Mujtaba M, Gamilla-Crudo A, Gugliuzza K, Aleter O, Shah S, Chapman Y, Reese J, Masood S, Taber T. Impact of Type 2 Surgical Injuries in Postmortem Donor Kidneys on the Post-Transplant Outcomes When Compared to Mate Non-Injured Kidney from the Same Donor. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/impact-of-type-2-surgical-injuries-in-postmortem-donor-kidneys-on-the-post-transplant-outcomes-when-compared-to-mate-non-injured-kidney-from-the-same-donor/. Accessed September 19, 2020.
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