Impact of Type 2 Surgical Injuries in Postmortem Donor Kidneys on the Post-Transplant Outcomes When Compared to Mate Non-Injured Kidney from the Same Donor.
1Division of Nephrology and Hypertension, University of Texas Medical Branch, Galveston, TX
2Department of Surgery, University of Texas Medical Branch, Galveston, TX
3Southwest Transplant Alliance, Dallas, TX
4Division of Nephrology, Indiana University, Indianapolis, IN
Meeting: 2017 American Transplant Congress
Abstract number: C146
Keywords: Donation, Graft acceptance, Graft function, Kidney transplantation
Session Information
Session Name: Poster Session C: Kidney Complications III
Session Type: Poster Session
Date: Monday, May 1, 2017
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall D1
Introduction – While damage to the procured organ is rare with organ loss being approximately 0.3% of procured organs, loss of potential transplantable organs does occur during procurement. The levels of damage range from a level of “0” (no damage); level “1” (minimal damage sustained upon procurement requiring no intervention); level “2” (damage sustained upon procurement requiring some surgical repair but not rendering the allograft non-transplantable); and finally level “3” (damage sustained upon procurement rendering the allograft non-transplantable). The clinical outcomes of organs with level 2 injuries are not known.
Methodology – At Southwest Transplant Alliance, we decided to follow the deceased donor kidneys with type 2 injuries and compared them to mate non injured kidney from the same donor. We identified 16 donors with type 2 injury on one of donated kidneys. We compared graft cold ischemia time (CIT), delayed graft function, early rejection, and graft survival. Unpaired T test was used for categorical variables and Fischer exact test for continuous variables. Mean follow-up was 157 days (33-390).
Results – There was no significant difference in cold ischemia time and delayed graft function in Type 2 injury kidney group vs. mate kidney group observed with a p value of 0.372 and 0.252, respectively. Rejection rates and graft survival between these two groups were also similar.
Conclusion – Based on our case series, it appears that type 2 kidney injury had no significant impact on immediate post-transplant outcomes. More robust data and collaborative organ procurement organization research efforts are required to completely understand the impact of these injuries on outcomes.
CITATION INFORMATION: Mujtaba M, Gamilla-Crudo A, Gugliuzza K, Aleter O, Shah S, Chapman Y, Reese J, Masood S, Taber T. Impact of Type 2 Surgical Injuries in Postmortem Donor Kidneys on the Post-Transplant Outcomes When Compared to Mate Non-Injured Kidney from the Same Donor. Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Mujtaba M, Gamilla-Crudo A, Gugliuzza K, Aleter O, Shah S, Chapman Y, Reese J, Masood S, Taber T. Impact of Type 2 Surgical Injuries in Postmortem Donor Kidneys on the Post-Transplant Outcomes When Compared to Mate Non-Injured Kidney from the Same Donor. [abstract]. Am J Transplant. 2017; 17 (suppl 3). https://atcmeetingabstracts.com/abstract/impact-of-type-2-surgical-injuries-in-postmortem-donor-kidneys-on-the-post-transplant-outcomes-when-compared-to-mate-non-injured-kidney-from-the-same-donor/. Accessed May 12, 2025.« Back to 2017 American Transplant Congress