How Evaluation for Living Kidney Donation Saved My Life
1Dept. of Endocrinology and Diabetology, Angiology, Nephrology and Clinical Chemistry, University of Tübingen, Tübingen, Germany
2Dept. of General, Visceral and Transplant Surgery, University of Tübingen, Tübingen, Germany.
Meeting: 2018 American Transplant Congress
Abstract number: D174
Keywords: Kidney, Malignancy, Metabolic disease, Prognosis
Session Information
Session Name: Poster Session D: Kidney Living Donor: Selection
Session Type: Poster Session
Date: Tuesday, June 5, 2018
Session Time: 6:00pm-7:00pm
Presentation Time: 6:00pm-7:00pm
Location: Hall 4EF
Purpose:In order to ensure eligibility for living kidney donation, donor candidates undergo a thorough medical evaluation. This evaluation process might reveal previously unknown medical conditions, leading to declination of the kidney donor candidate. However, detection of such medical conditions may have a lifesaving impact for kidney donor candidates. We report 10-year data from our living donor transplantation program on kidney donor candidates newly diagnosed with impactful medical conditions during the evaluation process.
Methods: A retrospective analysis of living kidney donor candidates since 2007 at the Tübingen Collaborative Transplant Center was performed. Focus was on newly diagnosed medical conditions requiring immediate attention and their prognostic significance.
Results: Since 2007, 341 potential living kidney donor candidates were evaluated, of which 157 (46%) donated a kidney. 174 candidates (51%) were declined, whereas 10 candidates (4%) are still under evaluation. Interestingly, 48 of the declined candidates (28%) were diagnosed with a medical condition requiring immediate attention within the process of donor evaluation. While 29 patients were newly diagnosed with diabetes mellitus, 8 patients were diagnosed with cardiac disease requiring intervention and 7 patients were diagnosed with malignancy. These newly diagnosed malignancies comprised neuroendocrine tumors of the bowel and abdomen, lymphoma, bronchial carcinoma, MGUS and renal cell carcinomas, which directly underwent curative treatment. The other 4 patients were newly diagnosed with chronic inflammatory bowel disease, active hepatitis B or primary sclerosing cholangitis, respectively.
In conclusion, the evaluation process for living kidney donation allowed for revelation of life changing diagnoses in a relevant proportion of candidates, requiring immediate medical attention in order not to affect life expectancy.
CITATION INFORMATION: Guthoff M., Mühlbacher T., Nadalin S., Heyne N. How Evaluation for Living Kidney Donation Saved My Life Am J Transplant. 2017;17 (suppl 3).
To cite this abstract in AMA style:
Guthoff M, Mühlbacher T, Nadalin S, Heyne N. How Evaluation for Living Kidney Donation Saved My Life [abstract]. https://atcmeetingabstracts.com/abstract/how-evaluation-for-living-kidney-donation-saved-my-life/. Accessed May 11, 2025.« Back to 2018 American Transplant Congress