2018 American Transplant Congress
Thrombotic Microangiopathy after Renal Transplantation: A Clinicopathological Study and Identification of Prognostic Factors
IntroductionThrombotic microangiopathy (TMA), whether de novo or recurrent, is a serious complication after renal transplantation, but prognostic factors and the role of complement inhibitors in…2018 American Transplant Congress
Development of an Individualized Online Shared Decision Making Tool for Kidney Transplant Candidates
Background: Inadequate knowledge hinders informed decision making in kidney transplant candidates. We conducted qualitative interviews and focus groups with patients and providers to inform development…2018 American Transplant Congress
Urinary C5b-9 is an Independent Predictor of Graft Failure in Renal Transplant Recipients
Department of Nephrology, University Medical Centre Groningen, Groningen, Netherlands.
IntroductionChronic antibody-mediated rejection is thought to be the main cause of late kidney-allograft loss, involving donor-specific antibody–mediated activation of the complement system. Activation of filtered…2018 American Transplant Congress
A Pre-Transplant Blood-Based Lipid Signature for Prediction of Antibody-Mediated Rejection in Kidney Transplant Patients
Virginia Commonwealth University, Richmond.
BACKGROUNDThere is a lack of biomarkers for pre-kidney transplant immune risk stratification to avoid over- or under-immunosuppression. Since the circulating lipidome is integrally involved in…2018 American Transplant Congress
An Integrative Approach for the Assessment of Peritubular Capillaritis Extent and Score in Microvascular Inflammation – Association with Transplant Glomerulopathy and Graft Loss
Background:Banff Classification accepts two histomorphological features as surrogates of HLA Antibody-Antigen interaction on renal endothelium: C4d staining and microvascular inflammation scores (MVI sum score:ptc+g≥2) which…2018 American Transplant Congress
Long-Term Social Outcome after Pediatric Kidney Transplantation
BackgroundPatients' and graft survival rates after pediatric kidney transplantation (KTx) were recently improved because of progress in immunosuppressants, perioperative care, and operative procedures. Therefore the…2018 American Transplant Congress
How Evaluation for Living Kidney Donation Saved My Life
Purpose:In order to ensure eligibility for living kidney donation, donor candidates undergo a thorough medical evaluation. This evaluation process might reveal previously unknown medical conditions,…2018 American Transplant Congress
Clinical Significance of Isolated v-Lesions in Kidney Transplantation
Background: Arteritis without significant tubulo-interstitial inflammation (v1-3, but i≤1 and t≤1) is referred by the 10th Banff conference as 'isolated v-lesions'. The clinical significance of…2017 American Transplant Congress
Assessment of the Risk Index for Living Donor Kidney Transplantation (LKDPI) in a European Cohort.
Nephrology, Charité Universitaetsmedizin, Berlin, Germany
Introduction: Recently, a risk index for living donor kidney transplantation (LKDPI) was proposed (Massie et al. AJT 2016) to compare living donor kidneys (LDK) to…2017 American Transplant Congress
A Multidimensional Prognostic Score and Nomogram to Predict Kidney Transplant Survival: The Integrative Box (iBox) System.
The transplant field currently lacks of robust risk stratification models leading to major problems for clinical care, clinical trials, and medical progress. The goal of…
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