ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Hepatic Artery Thrombosis in the Modern Era of Increased Utilization of Livers from Older Donors

A. Kernodle, M. Krach, P. Chiang, D. Segev, A. Massie, J. Garonzik-Wang

Johns Hopkins Hospital, Baltimore, MD

Meeting: 2020 American Transplant Congress

Abstract number: C-150

Keywords: Age factors, Graft failure, Hepatic artery, Liver transplantation

Session Information

Session Name: Poster Session C: Liver Retransplantation and Other Complications

Session Type: Poster Session

Date: Saturday, May 30, 2020

Session Time: 3:15pm-4:00pm

 Presentation Time: 3:30pm-4:00pm

Location: Virtual

*Purpose: In a prior study using national registry data, deceased donor age greater than 50 was associated with a 35% to 61% increased risk of hepatic artery thrombosis (HAT). There has been no contemporary evaluation of incident HAT in current landscape of deceased donor organ pool changes.

*Methods: We used SRTR data from 01/1990- 03/2019 to identify first-time adult deceased donor liver transplant recipients. We used cox regression to quantify the change in HAT incidence over time, adjusting for recipient age and sex. HAT was defined by graft failure or death due to vascular thrombosis within 90 days of transplant. We used linear regression to characterize changes in mean donor age over time.

*Results: We studied 109,797 liver transplant recipients. Between 1990 and 2005, the mean donor age increased yearly by 0.65 years (95% CI: 0.61-0.68). After 2005, mean donor age plateaued (Figure 1). Despite increasing donor age, the risk of HAT decreased significantly every 5 years during the study period (adjusted Hazard Ratio: 0.73, 95% CI: 0.72-0.74).

*Conclusions: The decline in HAT despite utilization of older donors likely reflects unmeasured factors that have allowed for more informed selection of deceased donor organs or improved donor-recipient matching.

Figure 1. HAT Events and Mean Donor Age over Time

 border=

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Kernodle A, Krach M, Chiang P, Segev D, Massie A, Garonzik-Wang J. Hepatic Artery Thrombosis in the Modern Era of Increased Utilization of Livers from Older Donors [abstract]. Am J Transplant. 2020; 20 (suppl 3). https://atcmeetingabstracts.com/abstract/hepatic-artery-thrombosis-in-the-modern-era-of-increased-utilization-of-livers-from-older-donors/. Accessed May 11, 2025.

« Back to 2020 American Transplant Congress

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences