2020 American Transplant Congress
Transition from Youth to Adult Care of Kidney Transplant Recipients: Single Center Experience
Pediatric Nephrology, Lucile Packard Children's Hospital, Stanford, CA
*Purpose: Transition of transplant recipients from youth to adult care has been a challenge for many. Starting in March 2017, Lucile Packard Children’s Hospital (LPCH)…2020 American Transplant Congress
Managing the Road to Kidney Transplantation in the Elderly
Nephrology, UPMC, Pittsburgh, PA
*Purpose: We hypothesize that careful patient selection and waitlist management minimizes the impact of advanced recipient age on kidney transplant outcomes.*Methods: A total of 3,521…2020 American Transplant Congress
Outcome of Large Donor-Recipient Age Gap in Live-Donor Renal Transplant in Tacrolimus Era
*Purpose: A large donor-to-recipient age gap among deceased-donor renal transplant (RT) patients leads to worse outcomes. However, the impact of this age gap among live-donor…2020 American Transplant Congress
Age Mismatch between Donor and Recipient in Heart Transplant and its Effect on Mortality
*Purpose: Increasing donor to recipient age difference has been shown to reduce survival in pediatric heart transplant population. However, the effect of age mismatch in…2020 American Transplant Congress
Age- and Sex-Mediated Differences in T Lymphocyte Populations of Kidney Transplant Recipients
*Purpose: Kidney allograft failure rates peak between 17 to 24 years of age and are higher in young female than male kidney transplant recipients (KTR).…2020 American Transplant Congress
T Cell Hyporesponsiveness in Kidney Transplant Recipients is Associated with Urinary Tract Infections and Age of Kidney Transplant: Implications for Allograft Nephropathy
Dept of Nephrology, University of KwaZulu-Natal, Durban, South Africa
*Purpose: Chronic allograft nephropathy is the main cause of kidney graft loss. With the use of potent immunosuppressive treatments, acute rejections are less and less…2020 American Transplant Congress
Donor and Recipient Sex Affect Transplant Outcomes in an Age-Specific Fashion
*Purpose: Donor and recipient sex impact transplant outcomes. The biology of sex-specific alloimmune responses has not been studied in detail.*Methods: Using clinical data from more…2020 American Transplant Congress
Targeting CD4+ T Cell Metabolism Prolongs Graft Survival Age-Specifically
*Purpose: If and how aging affects T-cell metabolism and alloimmune response is unclear. Here, we show that T-cell metabolism changes drastically in aging. Most notably,…2020 American Transplant Congress
Serum αKlotho after Living Kidney Donation: A Systematic Review and Meta-Analysis
*Purpose: αKlotho (klotho) is a known anti-aging protein that exerts diverse physiological effects. Defect in klotho gene expression in mice can result in a syndrome…2020 American Transplant Congress
Older Livers Should Not Be Utilized in Pediatric Liver Transplantation
*Purpose: Organ scarcity in liver transplantation has required expansion of the acceptable criteria used for donor selection. The utilization of older donors (>60 years) has…
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