2016 American Transplant Congress
The Treatment of Borderline Lesion in Protocol Biopsies Did Not Improve the Outcome in Kidney Transplant Recipients.
Introduction. Up to 30% of patients with protocol biopsies and stable renal function have borderline lesions. His relationship with acute rejection remains uncertain, as does…2016 American Transplant Congress
Lower Renal Graft Function and Accelerated Fibrosis in HIV-Infected Transplant Recipients with Previous HIVAN Compared to Non HIVAN HIV-Positive Transplant Recipients.
Several studies reported reduced renal allograft survival rates among HIV-infected transplant recipients. Few data focus on histological lesions and their progression in renal grafts from…2016 American Transplant Congress
Everolimus with Low-Dose Tacrolimus vs. a Standard Immunosuppressive Regimen: Renal Histology at 6 Months in De Novo Renal Transplant Patients.
Morphologic changes in transplant protocol biopsies provide early evidence of renal damage. This study examined the renal histology of de novo patients 6 months post…2016 American Transplant Congress
Randomized Controlled Study Evaluating Adherence Monitoring with Electronic Feedback on Reducing Renal Allograft Rejection.
Transplant Center, University of Chicago, Chicago, IL.
Purpose: The negative impact of non-adherence to the immunosuppressant medication (IM) regimen on transplant outcomes is well recognized. In an attempt to improve outcomes, the…2016 American Transplant Congress
Association of Ultrastructural Changes in Renal Allograft Biopsies with Antibody-Mediated Rejection (AMR) and Graft Outcomes.
The role of electron microscopy (EM) in diagnosis of AMR is not well-defined. We sought to examine the EM findings in 796 biopsies from 622…2016 American Transplant Congress
Kidney Structural Characteristics as Predictors of Long-Term Kidney Function in Living Kidney Donors.
PurposeKidney structural characteristics may be predictive of long-term living donor outcomes such as a lower estimated Glomerular Filtration Rate (eGFR).MethodsAs part of the Renal and…2016 American Transplant Congress
Natural Language Processing Methods Allow Reliable Extraction of Banff Scores and Grades.
Objective: National Data are sparse with regard to pathology of rejection. Incorporating biopsy pathology grades and lesion scores into analyses requires manual extraction and entry…2016 American Transplant Congress
Arteriolar Hyalinosis on Renal Transplant Protocol Biopsies Is Not Associated with Tacrolimus Exposure.
Previous studies have implicated the development of arteriolar hyalinosis (AH) following kidney transplantation to chronic calcineurin inhibitor nephrotoxicity. Here, we examined the association between tacrolimus…2016 American Transplant Congress
The Effect of Everolimus and Tacrolimus Exposure Levels on Renal Histology Parameters 6 Months Post-Transplantation.
We examined renal histology scores in patients with different exposure levels of everolimus (EVR) and tacrolimus (TAC) over 6 months.Renal transplant patients (N=613) were randomized…2016 American Transplant Congress
Using Gastrointestinal Biopsy to Predict Outcome in Patients Evaluated for Cardiac Transplantation for Amyloidosis: A Report from the International Consortium on Cardiac Amyloidosis Transplantation (iCCAT).
Heart transplant (HT) is an established therapy for heart failure due to amyloidosis. The utility of gastrointestinal (GI) biopsy in predicting patient outcomes and guiding…
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