ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Articles tagged "Xenotransplantation"

  • 2018 American Transplant Congress

    Rhesus Monkey Have natural Antibody toward Swine That is Not Influenced by Allosensitization nor by Carfilzomib/tocilizumab

    J. Yoon, B. Ezekian, M. Manook, J. Kwun, S. Knechtle.

    Surgery, Duke University, Durham, NC.

    [Background] Pre-formed antibody is a substantial immunological barrier in organ transplantion. Antibodies to xenoantigens can lead to rapid antibody-mediated rejection (AMR) in xenotransplantation. We previously…
  • 2018 American Transplant Congress

    Re-Endothelialization of Liver Xenografts Utilizing Human Endothelial Cells

    W. Hassanein,1 P. Patel,1 A. Werdsheim,1 J. Brilliant,1 E. Buckingham,1 N. Shockcor,1 C. Drachenberg,2 R. Barth,1 J. LaMattina.1

    1Surgery, University of Maryland, Baltimore, MD; 2Pathology, University of Maryland, Baltimore, MD.

    Introduction:Acute antibody mediated rejection due to preformed antibodies present in human serum remains a hurdle to successful xenotransplantation. Xenograft vascular endothelium represents the initial site…
  • 2018 American Transplant Congress

    The Effect of Intravenous Immunoglobulin on In Vitro Human Antibody Binding to Genetically-Engineered Pig Cells – Relevance to Clinical Xenotransplantation –

    T. Yamamoto,1 Q. Li,1 H. Iwase,1 D. Ayares,2 D. Cooper,1 H. Hara.1

    1Xenotransplantation Program, Department of Surgery, University of Alabama at Birmingham, Birmingham; 2Revivicor, Blacksburg.

    Background: Xenoreactive antibodies play an important role in xenograft rejection. Intravenous immunoglobulin (IVIG), which has anti-complement activity and contains anti-idiotypic antibodies, is widely used for…
  • 2018 American Transplant Congress

    Successful Patency in Blood Conduits for an Artificial Kidney Membrane with Biocompatible Coatings

    R. Forbes,1 E. Marsh,1 S. Karp,1 A. Buck,1 D. Colvin,1 P. Williams,1 B. Chaudhuri,2 S. Roy,2 W. Fissell.1

    1VUMC, Nashville; 2UCSF, San Francisco.

    BACKGROUND: An implantable artificial kidney may address the growing organ shortage and improve outcomes and quality of life for those with end stage renal disease.…
  • 2018 American Transplant Congress

    An Effective Tolerance Approach for Porcine Islet Xenotransplantation in Humanized Mice

    F. Lee,1 A. Dangi,1 M. Burnette,1 X. Zhang,1 B. Hering,2 X. Luo.1

    1Comprehensive Transplant Center, Northwestern University, Chicago, IL; 2Diabetes/Endocrinology, Diabetes Institute, Minneapolis, MN.

    Purpose: Tolerance for pig-to-human islet transplantation could render a feasible and sustainable cure for T1D. We have previously described a triple therapy (TT) approach consisting…
  • 2018 American Transplant Congress

    Experience in the Development of a Life-Supporting Large Animal Orthotopic Cardiac Xenotransplant Model

    L. DiChiacchio,1 A. Singh,1 B. Lewis,1 E. Strauss,1 P. Odonkor,1 B. Williams,1 D. Ayares,2 K. Deatrick,1 Z. Kon,1 M. Mohiuddin.1

    1Cardiac Surgery, University of Maryland Medical Center, Baltimore, MD; 2Chief Scientific Office, Revivicor, Inc., Blacksburg, VA.

    Advances in clinical immunosuppression and characterization of optimal donor genetics continue to move the field of xenotransplantation toward a clinical reality with extremely long-term survival…
  • 2018 American Transplant Congress

    The Role of CD46 in Early Islet Engraftment in a Dual Transplant Model

    Q. Gao, K. Samy, R. Davis, M. Song, A. MacDonald, F. Leopardi, T. How, K. Williams, G. Devi, B. Collins, A. Kirk.

    Department of Surgery, Duke University School of Medicine, Durham, NC.

    IntroductionMembrane cofactor protein (CD46) is known to attenuate the complement cascade by facilitating cleavage of C3b and C4b. In solid organ xenotransplantation, organs expressing CD46…
  • 2018 American Transplant Congress

    Parathyroid Cell Xenotransplantation with Ultrapure Alginate Based Microencapsulation Technique

    B. Goncu,1 E. Yucesan,2 H. Basoglu,3 M. Celikten,1 O. Huseyinbas,1 B. Ozdemir,1 N. Ozten Kandas,4 F. Akbas,5 Y. Ersoy,6 E. Aysan.6

    1Bezmialem Vakif University, Experimental Research Center, Istanbul, Turkey; 2Bezmialem Vakif University, Institute of Life Sciences and Biotechnology, Istanbul, Turkey; 3Bezmialem Vakif University, Faculty of Medicine, Department of Biophysics, Istanbul, Turkey; 4Bezmialem Vakif University, Faculty of Pharmacy, Department of Pharmaceutical Toxicology, Istanbul, Turkey; 5Bezmialem Vakif University, Faculty of Medicine, Department of Medical Biology, Istanbul, Turkey; 6Bezmialem Vakif University, Faculty of Medicine, Department of General Surgery, Istanbul, Turkey.

    Permanent hypoparathyroidism (PH) is a serious clinical condition and unique treatment option is parathyroid allotransplantation (PA). The most important obstacle for PA is an immune…
  • 2018 American Transplant Congress

    Prevention of an Adaptive Immune Response by FDA-Approved Immunosuppressive Agents in Baboons with Pig Artery Patch Xenografts

    T. Yamamoto,1 H. Hara,1 L. Wang,1 Q. Li,1 J. Li,1 H. Zhou,1 D. Eckhoff,1 A. Tector,1 D. Ayares,2 D. Cooper,1 H. Iwase.1

    1Xenotransplantation Program, Department of Surgery, University of Alabama at Birmingham, Birmingham; 2Revivicor, Blacksburg.

    Background: In the pig-to-baboon artery patch model with no immunosuppressive therapy, a graft from a GTKO pig elicits a significant anti-nonGal IgG response, indicating sensitization…
  • 2018 American Transplant Congress

    Effects of Preformed Antibody on Survival Following Pig-to-Primate Liver Xenotransplantation

    N. Louras, M. Patel, J. Shah, A. Andrews, Z. Wang, D. Sachs, P. Vagefi.

    Transplant Surgery, Massachusetts General Hospital, Boston, MA.

    Objectives:Xenotransplantation represents the best near-term solution to address the current organ shortage. We have developed a pre-clinical model of pig-to-primate liver xenotransplantation (LXT), and now…
  • 1
  • 2
  • 3
  • …
  • 8
  • Next Page »

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences