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Articles tagged "Xenoreactive antibodies"

  • 2017 American Transplant Congress

    The Role of Anti-Neu5Gc IgM in Xenograft Antibody Mediated Rejection.

    W. Hassanein,1 G. Braileanu,1 L. Burdorf,1 W. Sun,1 B. French,1 C. Laird,1 S. Sendil,1 C. Ahn,3 D. Ayares,2 R. Pierson III,1 A. Azimzadeh.1

    1University of Maryland School of Medcine, Baltimore, MD; 2Revivicor, Blacksburg, VA; 3Seoul National University Hospital, Seoul, Korea

    Background:Acute antibody mediated rejection due to preformed antibodies present in human serum remains a hurdle to successful xenotransplantation. Here, we measured anti-Neu5Gc-IgM antibody titers in…
  • 2016 American Transplant Congress

    Impact of Mixed Xenogeneic Chimerism on Human B Cell Response to Pig Antigens.

    H. Li, S. Shao, P. Vishwasrao, M. Holzl, M. Sykes.

    Columbia Center for Translational Immunology, Columbia University, New York, NY.

    Xenotransplantation is a potential solution to the organ shortage in clinical transplantation. Pigs are regarded as the most suitable donors. Studies in pig-to-nonhuman primates have…
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