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Articles tagged "Viral therapy"

  • 2020 American Transplant Congress

    Preemptive Direct Acting Antiviral Therapy as Prophylaxis in Donor HCV-Positive to Recipient HCV-Negative Solid Organ Transplant: a Comprehensive Review

    M. Mavuram, S. Mavuram, H. Samant, S. Pandit, B. Samant, J. Morris, J. Alexander

    Gastroenterology, Louisiana State University of Health Sciences Shreveport, Shreveport, LA

    *Purpose: With the advent of highly effective and safe oral Direct acting Antiviral agents (DAAs), several transplant centers have adopted protocols for using HCV positive…
  • 2020 American Transplant Congress

    Cytomegalovirus Infection and Outcomes in Pancreas Transplant Recipients in the Prophylaxis Era

    M. Jorgenson1, N. Marka2, G. Leverson2, J. Smith2, J. Odorico2

    1UW Health, Madison, WI, 2UWMF, Madison, WI

    *Purpose: Evaluate epidemiology and outcomes of cytomegalovirus infection (CMV) in pancreas transplant recipients (PTR) in the current era of valganciclovir (VGC) prophylaxis (PPX)*Methods: Adult PTRs…
  • 2020 American Transplant Congress

    Comparison of Prophylaxis Strategies for CMV Infection in Liver Transplant Recipients

    K. Schnelle, A. Leino, M. Chunduru, L. Von Stein, O. Witkowsky

    The Ohio State Wexner Medical Center, Columbus, OH

    *Purpose: The best strategy to prevent cytomegalovirus (CMV) following liver transplantation is not defined for intermediate risk recipients (recipient seropositive (R+) regardless of donor status).…
  • 2020 American Transplant Congress

    Brincidofovir for Adenovirus Disease in Adult Renal Transplant Recipients: A Case Series

    F. Zervou1, I. Zacharioudakis1, S. A. Mehta2, H. J. Neumann2

    1Infectious Diseases, New York University Langone, New York, NY, 2New York University Langone Transplant Institute, New York, NY

    *Purpose: Adenovirus infection can lead to disease in solid organ transplant recipients, including disease of the allograft. Treatment options for severe disease are limited. Brincidofovir…
  • 2020 American Transplant Congress

    Utilization of Organs from Donors Exposed to Hepatitis C: ? Standard of Care

    M. Marvin1, S. Gaines2, P. Mohan3, A. Kotru1, C. Koo1, B. Addissie4, A. Unzueta4, S. Khurana4

    1Transplantation and Liver Surgery, Geisinger, Danville, PA, 2Pharmacy, Geisinger, Danville, PA, 3Nephrology, Geisinger, Danville, PA, 4Hepatology, Geisinger, Danville, PA

    *Purpose: To report the results of a clinical program to utilize livers and kidneys from donors exposed to Hepatitis C.*Methods: We initially started to explore…
  • 2020 American Transplant Congress

    Viral Kinetics of De Novo HCV Infection and Response to Antiviral Therapy in Liver and Kidney Transplant Recipients Receiving HCV-Viremic Donors

    N. Terrault1, J. Burton2, E. Verna3, C. Mobley4, D. Victor4, J. Trotter5, C. Niemann6, R. Rubin7

    1University of Southern California, Los Angeles, CA, 2UC, Denver, CO, 3Columbia Universeity, New York, NY, 4Houston Methodist, Houston, TX, 5Baylor University, Dallas, TX, 6UCSF, San Francisco, CA, 7Piedmont Atlanta Hosptial, Atlanta, GA

    *Purpose: There is general agreement that expanded use of organs from HCV-viremic donors is desirable, including in recipients without HCV infection. However, the optimal treatment…
  • 2019 American Transplant Congress

    Oral Ribavirin Therapy for Respiratory Syncytial Virus (RSV) in Lung Transplant Recipients: The Impact of Policy Implementation on Cost and Appropriate Use

    B. Berak, N. Sulejmani, A. Jantz, T. Larson, S. Davis, B. Summers

    Henry Ford Hospital, Detroit, MI

    *Purpose: RSV is a leading cause of viral infections in lung transplant recipients and is associated with significant morbidity and mortality. While the role of…
  • 2019 American Transplant Congress

    REHANNA: Renal Transplants in Hepatitis C Negative Recipients with Nucleic Acid Positive Donors with Short Course Direct Acting Antiviral Prophylaxis

    C. Durand, B. Barnaba, D. Brown, N. Bair, F. Naqvi, M. Bowring, D. Segev, M. Sulkowski, N. Desai

    Johns Hopkins University School of Medicine, Baltimore, MD

    *Purpose: To mitigate the current organ shortage and underutilization of hepatitis C-infected deceased donor (HCV D+) organs, we evaluated the use of HCV D+ kidneys…
  • 2019 American Transplant Congress

    Long-Term Efficacy of Direct-Acting Antiviral Agents

    J. Zhang, W. Sun, J. Lin, Y. Tian, L. Ma, L. Zhang, Y. Zhu

    Beijing Friendship Hospital, Capital Medical University, Beijing, China

    *Purpose: Long-term efficacy of direct-acting antiviral agents (DAAs) therapy in kidney transplant recipients was unknown. Thus, we aimed to evaluate it in a Chinese cohort…
  • 2019 American Transplant Congress

    Excellent Success with Safety and Efficacy of Direct-Acting Anti-Viral HCV Drugs in Kidney Transplant Recipients Using an Evolving Regimen. A Single Institution Experience

    A. Sharfuddin, S. A. Hussain, T. Taber, D. Mishler, O. Adebiyi, M. S. Yaqub

    Indiana University School of Medicine, Indianapolis, IN

    *Purpose: Chronic Hepatitis C Virus (HCV) infection has a negative impact on graft survival. Prior treatments were poorly tolerated and had minimal cure rates. We…
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