ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Vascular disease"

  • 2016 American Transplant Congress

    Pre-Transplant Cardiovascular Risk Factors Affect Kidney Allograft Survival: A Multi-Center Study in Korea.

    J. An,1,2 S. Ahn,3 E. Bae,2 E. Kang,2 H.-L. Kim,4 Y.-J. Kim,5 Y. Oh,1,2 C. Lim,1,2 Y. Kim,2 Y. Kim,6 J. Lee.1,2

    1Division of Nephrology, Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; 2Division of Nephrology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; 3Department of Preventive Medicine, Yonsei University Wonju College of Medicine, Wonju, Gangwon-do, Korea; 4Division of Cardiology, Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; 5Division of Cardiology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; 6Department of Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea.

    Background - Pre- or post-transplant cardiovascular (CV) risk factors affect the development of CV events even after successful kidney transplantation (KT). However, the impact of…
  • 2016 American Transplant Congress

    Outcomes of EVAR in Kidney Transplant Recipients: Results form a National Quality Initiative.

    I. Bostock,1 D. Zarkowsky,1 D. Stone,1 M. Eslami,2 M. Malas,3 P. Goodney.1

    1Vascular Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH; 2Vascular Surgery, Boston Medical Center, Boston, MA; 3School of Public Health, John Hopkins Medical School, Baltimore, MD.

    BACKGROUND:Contrast-induced nephropathy following endovascular aortic aneurysm repair (EVAR) in renal transplant patients can have devastating consequences. We describe outcomes within a national cohort of kidney…
  • 2016 American Transplant Congress

    Exosome-Like Vesicles Released in Association with Tissue Injury Trigger Anti-LG3 Production.

    M. Dieudé,1,2,3 J. Turgeon,1,3 B. Yang,1,2,3 L. Pomerleau,1,3 K. Hamelin,1,3 S. Lan,1,2,3 S. Qi,1,3 D. Gingras,1,3 W. Dhari,1 A. Rivard,1 M.-J. Hébert.1,2,3

    1Research Centre, Centre hospitalier de l'Université de Montréal, Montréal, Canada; 2Université de Montréal, Montréal, Canada; 3Canadian National Transplantation Research Program, Edmonton, Canada.

    Pre-transplant levels of autoantibodies to perlecan/LG3 predict poor allograft outcomes in renal transplant patients. We showed previously thatapoptotic exosome-like vesicles (ApoExo) enhance anti-LG3 production and…
  • 2016 American Transplant Congress

    Air Pollution – An Additional Risk Factor for Developing Cardiac Allograft Vasculopathy.

    C. Bara, D. Böthig, Y. Scheibner, D. Bobylev, B. Przybylek, A. Haverich.

    Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.

    Purpose:Cardiac allograft vasculopathy (CAV) remains one of the primary causes of death in long-term follow-up after heart transplantation (HTx) and is the most limiting factor…
  • 2015 American Transplant Congress

    Longitudinal Follow-Up of Cardiovascular Comorbidity in Pediatric Renal Transplant Recipients – Results from the 4C-T Study

    A. Melk,1 D. Thurn-Valsassina,1 B. Schmidt,1 A. Duzova,2 B. Soezeri,3 A. Bayazit,4 S. Caliskan,5 U. Querfeld,6 K. Ažukaitis,7 E. Wuehl,7 F. Schaefer.7

    1Hannover Medical School, Hannover, Germany; 2Hacettepe University Medical Faculty, Ankara, Turkey; 3Ege University Medical Faculty, Izmir, Turkey; 4Cukurova University, Faculty of Medicine, Adana, Turkey; 5Istanbul University Cerrahpasa Medial School, Istanbul, Turkey; 6Charité Universitätsmedizin Berlin, Berlin, Germany; 7Centre for Pediatric and Adolescent Medicine, Heidelberg, Germany.

    Purpose: Children with chronic kidney disease (CKD) carry an increased cardiovascular risk. Cardiovascular death is the second leading cause of death in children after renal…
  • 2015 American Transplant Congress

    Inhibition of RhoA Pathway-Related Macrophage Functions Abrogates Chronic Rejection of Cardiac Allograft

    M. Kloc, J. You, N. Tejpal, X. Li, R. Ghobrial.

    TMHRI, Houston, TX.

    Objective. Chronic rejection remains the main obstacle in the long-term success of organ transplantation. The long-term survival of allografted hearts is limited by a progressive…
  • 2015 American Transplant Congress

    Survival of Patients With Peripheral Vascular Disease on Kidney Waitlist and After Transplantation: An Analysis of the United State Renal Data System

    A. Brar,1 D. Stefanov,3 R. Jindal,2 N. Sumrani,4 D. John,4 F. Tedla,1 M. Salifu.1

    1Department of Medicine, SUNY Downstate Medical Center, Brooklyn, NY; 2Department of Surgery, Walter Reed National Military Medical Center, Uniformed Services University of Health Sciences, Bethesda, MD; 3Division of Research, SUNY Downstate School of Medicine, Brooklyn, NY; 4Department of Surgery, SUNY Downstate Medical Center, Brooklyn, NY.

    Introduction: There is lack of information whether waitlisted dialysis patients with peripheral vascular disease (PVD) benefit from kidney transplantation.Methods: We used a cohort of USRDS…
  • 2015 American Transplant Congress

    Conditioning of Mesenchymal Stromal Cells With mTOR Inhibitor Enhances Regenerative Properties of Secretome and Attenuates Vascular Calcification

    B. Hegner,1 C. Kurth,1 T. Schaub,1 C. Lange,2 D. Dragun.1

    1Clinic for Nephrology and Intensive Care Medicine, Charité University Hospital, Berlin, Germany; 2Department of Cell and Gene Therapy, University Medical Center Eppendorf, Hamburg, Germany.

    Similar to patients with chronic kidney disease, recipients of kidney transplants are a high-risk population for cardiovascular events due to arterial media calcification in particular…
  • 2015 American Transplant Congress

    Progression of Coronary Artery Disease in High-Risk Patients Undergoing Renal Transplantation

    R. Corbett, N. Kumar, C. Baker, D. Moutzouris, M. Willicombe, J. Galliford, A. McLean, N. Duncan, D. Taube.

    Imperial College Renal and Transplant Centre, London, United Kingdom.

    Asymptomatic coronary artery disease [CAD] is common in patients with end-stage renal disease [ESRD]. While coronary revascularization prior to transplantation is associated with improved patient…
  • 2015 American Transplant Congress

    Evaluating the Benefits of Everolimus on Cardiac Allograft Vasculopathy: Further Evidence from Results of Imputations for Missing IVUS Data from A2310 Study

    P. Lopez,1 G. Dong,2 Z. Wang.2

    1Novartis Pharma AG, Basel, Switzerland; 2Novartis Pharmaceuticals, East Hanover, NJ; 3Novartis Pharmaceuticals, East Hanover, NJ.

    Purpose: A2310 IVUS study showed that everolimus (EVR) provides cardiac allograft vasculopathy (CAV) benefit compared to mycophenolate mofetil (MMF) by assessing the mean change in…
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