Articles tagged "Vaccination"

2022 American Transplant Congress
Immunogenicity of a Quadrivalent Human Papillomavirus Vaccine in Pediatric Kidney and Liver Transplant Recipients
T. Kitano¹, K. Schwartz², M. Abdulnoor¹, H. Garfield³, N. K. Booran¹, Y. Avitzur¹, C. Teoh¹, D. Hebert⁴, U. Allen³
¹Hospital for Sick Children, Toronto, ON, Canada, ²Public Health Ontario, Toronto, ON, Canada, ³University of Toronto, Toronto, ON, Canada, ⁴The Hospital for Sick Children, Toronto, ON, Canada
*Purpose: Solid-organ transplant recipients are at increased risk of developing human papillomavirus (HPV)-related diseases. The immunogenicity of HPV vaccine for solid-organ transplant population needs further…
2022 American Transplant Congress
Pre-Transplant Vaccine Induced SARS-CoV-2 Antibodies Decrease Following Induction Therapy for Kidney Transplantation
N. Barros¹, A. C. Ermel¹, A. Sharfuddin², W. Goggins³, J. Fridell²
¹Indiana University, Indianapolis, IN, ²Indiana University School of Medicine, Indianapolis, IN, ³Indiana University Hospital, Indianapolis, IN
*Purpose: Kidney transplant recipients (KT) and wait-listed individuals exhibit an impaired response to vaccinations. There is currently no data on the impact of induction immunosuppression…
2022 American Transplant Congress
Outcomes of COVID-19 in Solid Organ Transplant Recipients in Canada 2020-2021: A Prospective, Multicenter Cohort Study
V. G. Hall¹, G. Alahmadi², J. T. Solera², T. Marinelli², H. Cardinal³, G. Prasad⁴, S. A. De Serres⁵, D. Isaac⁶, R. Mainra⁷, C. Lamarche⁸, R. Sapir-Pichhadze⁹, S. Gilmour¹⁰, A. Humar², D. Kumar²
¹University Health Network/Toronto General Hospital, Toronto, ON, Canada, ²UHN, Toronto, ON, Canada, ³UMontreal, Montreal, QC, Canada, ⁴StMH, Toronto, ON, Canada, ⁵Laval U, Quebec, QC, Canada, ⁶UCalgary, Calgary, AB, Canada, ⁷USaskatchewan, Saskatoon, SK, Canada, ⁸HMR, Montreal, QC, Canada, ⁹McGill U, Montreal, QC, Canada, ¹⁰SCH, Edmonton, AB, Canada
*Purpose: To understand the outcomes and changes in disease severity of COVID-19 in Solid Organ Transplant (SOT) recipients over time in the context of therapeutic…
2022 American Transplant Congress
Comparison of Outcomes of Covid-19 Between Fully Vaccinated and Unvaccinated Kidney Transplant Recipients and According to the Type of M-RNA Vaccine
F. Villanego¹, M. Crespo², V. Lopez³, S. Zarraga⁴, F. Oppenheimer⁵, L. Llinas², A. Andres⁶, C. Diaz⁷, M. Ruiz⁸, F. Moreso⁹, A. Rodriguez-Benot¹⁰, I. Beneyto¹¹, S. Cabello¹², C. Jimenez¹³, C. Canal¹⁴, M. Molina¹⁵, J. Pascual⁶, A. Mazuecos¹
¹Department of Nephrology, Hospital Puerta del Mar, Cadiz, Spain, ²Department of Nephrology, Hospital del Mar, Barcelona, Spain, ³Department of Nephrology, Hospital Regional de Malaga, Malaga, Spain, ⁴Department of Nephrology, Hospital de Cruces, Baracaldo, Spain, ⁵Department of Nephrology, Hospital Clinic, Barcelona, Spain, ⁶Department of Nephrology, Hospital 12 de Octubre, Madrid, Spain, ⁷Department of Nephrology, Hospital Central de Asturias, Oviedo, Spain, ⁸Department of Nephrology, Hospital Virgen de las Nieves, Granada, Spain, ⁹Department of Nephrology, Hospital Vall d'Hebron, Barcelona, Spain, ¹⁰Department of Nephrology, Hospital Reina Sofia, Cordoba, Spain, ¹¹Department of Nephrology, Hospital La Fe, Valencia, Spain, ¹²Department of Nephrology, Hospital Son Espases, Palma de Mallorca, Spain, ¹³Department of Nephrology, Hospital La Paz, Madrid, Spain, ¹⁴Department of Nephrology, Fundacion Puigvert, Barcelona, Spain, ¹⁵Department of Nephrology, Hospital Germans Trias i Pujol, Badalona, Spain
*Purpose: The evidence regarding the clinical effectiveness of COVID-19 vaccination in kidney transplant (KT) recipients is limited so far. Our purpose is to analyze the…
2022 American Transplant Congress
Immunogenicity and Safety of SARS-CoV-2 Vaccines and Breakthrough Infections Among Solid Organ Transplant Recipients: Systematic Review and Meta-Analysis
A. Villavicencio¹, Y. Ebisu², M. Raja³, A. P. Sanchez-Covarrubias¹, S. Anjan³, J. M. Reynolds¹, J. Simkins³, J. Camargo³, M. I. Morris³, L. Abbo⁴, G. Guerra⁵, Y. Natori⁶
¹Internal Medicine, University of Miami Miller School of Medicine, Miami, FL, ²Kameda Medical Center, Chiba, Japan, ³University of Miami Miller School of Medicine, Miami, FL, ⁴University Of Miami Miller School of Medicine, Miami, FL, ⁵University of Miami Jackson Memorial Hospital, Miami, FL, ⁶University of Miami, Pinecrest, FL
*Purpose: The SARS-CoV-2 pandemic has had a significant impact on the field of solid organ transplant(SOT). Immunization against SARS-CoV-2 is globally available since 2021. SOT…
2022 American Transplant Congress
International Practices on COVID-19 Vaccine Mandates for Transplant Candidates
Y. Caliskan¹, B. E. Hippen², D. Axelrod³, M. Schnitzler¹, K. Maher¹, T. Alhamad⁴, S. Anwar⁵, V. Kute⁶, K. Lentine¹
¹Saint Louis University, Saint Louis, MO, ²Transplant Medicine, Fresenius Medical Care, Charlotte, NC, ³University of Iowa, Iowa City, IA, ⁴Washington University School of Medicine at St. Louis, Saint Louis, MO, ⁵Sheikh Shakhbout Medical Hospital, Abu Dhabi, United Arab Emirates, ⁶Dr. H L Trivedi Institute of Transplantation Sciences, Ahmedabad, India
*Purpose: The coronavirus disease 2019 (COVID-19) pandemic has created unprecedented challenges and there are practice differences for solid organ transplant programs worldwide. We sought to…
2022 American Transplant Congress
Comparison of Outcomes and Management of COVID Infection Among Kidney Transplant Recipients Between Pre-Vaccination Rollout Era and Post-Vaccination Rollout Era
G. Uehara¹, K. Soliman², V. Rao², M. Casey², D. Taber³, M. Posadas Salas²
¹Medical University of South Carolina, Charleston, SC, ²Nephrology, Medical University of South Carolina, Charleston, SC, ³Transplant Surgery, Medical University of South Carolina, Charleston, SC
*Purpose: The COVID pandemic has posed a significant challenge among kidney transplant recipients (KTR) due to their immunocompromised states. The effects of COVID vaccination on…
2022 American Transplant Congress
The Impact of Frailty Syndrome on Humoral Response to SARS-CoV-2 mRNA Vaccines in Older Kidney Transplant Recipients
M. Schmalz¹, H. Vankova², S. Rajnochova-Bloudickova¹, P. Hruba³, M. Fialova⁴, J. Gurka⁵, M. Magicova¹, I. Striz⁴, I. Zahradka¹, O. Viklicky¹
¹Department of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ²The Third Faculty of Medicine, Charles University, Prague, Czech Republic, ³Transplantation Laboratory, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ⁴Department of Immunology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ⁵Department of Information Technology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
*Purpose: Advanced age is associated with impaired humoral immune response to SARS-CoV-2 mRNA vaccines in kidney transplant recipients (KTR), however mechanisms are poorly understood. Frailty…
2022 American Transplant Congress
Impaired Humoral Response to Second Dose of BNT162b2 Messenger RNA COVID-19 Vaccine in Kidney Transplant Recipients in Japan: Prospective Observational Study
H. Sasaki¹, K. Hasegawa¹, M. Miura², H. Harada¹, D. Takamoto¹, Y. Takada¹, S. Harada¹, H. Tanaka¹
¹Sapporo City General Hospital, Sapporo, Japan, ²Sapporo Hokuyu Hospital, Sapporo, Japan
*Purpose: The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has a major impact on solid organ transplant (SOT) recipients, with mortality rate up to 22%. The…
2022 American Transplant Congress
Pre-Vaccine Antibodies Against Seasonal Betacoronaviruses Are Associated with Decreased Antibody Response to SARS-CoV-2 mRNA Vaccination in Solid Organ Transplant Recipients
A. Karaba¹, W. Zhou¹, T. Aytenfisu¹, T. S. Johnston¹, O. Akinde¹, Y. Eby¹, A. Abedon¹, J. Alejo¹, C. Qin¹, J. Garonzik-Wang², S. Klein¹, J. Bailey¹, A. Cox¹, J. Blankson¹, D. Segev¹, A. Tobian¹, W. Werbel¹
¹Johns Hopkins University, Baltimore, MD, ²University of Wisconsin School of Medicine and Health, Madison, WI
*Purpose: The impact of antigenic imprinting, when immune memory of one antigen influences the response to subsequent similar antigens, on the antibody response in solid…