2022 American Transplant Congress
The Impact of Frailty Syndrome on Humoral Response to SARS-CoV-2 mRNA Vaccines in Older Kidney Transplant Recipients
*Purpose: Advanced age is associated with impaired humoral immune response to SARS-CoV-2 mRNA vaccines in kidney transplant recipients (KTR), however mechanisms are poorly understood. Frailty…2022 American Transplant Congress
Impaired Humoral Response to Second Dose of BNT162b2 Messenger RNA COVID-19 Vaccine in Kidney Transplant Recipients in Japan: Prospective Observational Study
1Sapporo City General Hospital, Sapporo, Japan, 2Sapporo Hokuyu Hospital, Sapporo, Japan
*Purpose: The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has a major impact on solid organ transplant (SOT) recipients, with mortality rate up to 22%. The…2022 American Transplant Congress
Pre-Vaccine Antibodies Against Seasonal Betacoronaviruses Are Associated with Decreased Antibody Response to SARS-CoV-2 mRNA Vaccination in Solid Organ Transplant Recipients
*Purpose: The impact of antigenic imprinting, when immune memory of one antigen influences the response to subsequent similar antigens, on the antibody response in solid…2022 American Transplant Congress
Impact of Immunosuppressive Medications on SARS-CoV-2 Vaccination Response in Kidney Transplant Patients
*Purpose: The COVID-19 pandemic portends significant morbidity and mortality in immunocompromised individuals. Vaccination against COVID-19 among immunocompromised population is an essential step to minimize deadly…2022 American Transplant Congress
Effect of Sars-CoV-2 Delta Variant on Post-Vaccination COVID-19 Infection in Solid Organ Transplant Recipients
*Purpose: In July 2021, the SARS-CoV-2 Delta variant emerged as the dominant strain in the North Texas area. We reviewed COVID-19 infections post-vaccination in Solid Organ…2022 American Transplant Congress
Pericardial Effusion: A Potential Late Complication of COVID-19 Infection
Internal Medicine, Division of Nephrology, University of Texas Medical Branch, Galveston, TX
*Purpose: COVID-19 infection involves entry of SARS-CoV-2 virus into cells via interaction between its spike protein and angiotensin converting enzyme resulting in an NF-κβ mediated…2022 American Transplant Congress
Antibody Response to Sars- Cov -2 Mrna Vaccine in Kidney Transplant Recipients
Nephrology, Hamad Medical Corporation, Doha, Qatar
*Purpose: Kidney transplant recipients are vulnerable to develop severe form of COVID19 Infection. Although severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA vaccine has significantly…2022 American Transplant Congress
Kidney Transplantation from Deceased Donors with Vaccine-Induced Thrombosis and Thrombocytopenia: An Updated Analysis of the UK Experience
NHS Blood and Transplant, Bristol, United Kingdom
*Purpose: Vaccine-induced thrombosis and thrombocytopenia (VITT) is a rare syndrome that has emerged since widespread vaccination against SARS-CoV-2. As a result of the high mortality,…2022 American Transplant Congress
Multicenter Effort Assessing the Effects of COVID Infection and Vaccination on HLA Antibodies in Waitlisted Patients with ESRD
*Purpose: Although rare, infection and vaccination have been reported to result in human leukocyte antibodies (HLA). We analyzed the effect of SARS-CoV2 infection, or COVID-19…2022 American Transplant Congress
Third Dose of SARS-CoV-2 mRNA Vaccines Significantly Increases Delta (B.1.617.2) Variant Anti-Spike Antibody Levels in Kidney Transplant Recipients
1Massachusetts General Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA
*Purpose: Emerging SARS-CoV-2 variants may be associated with a higher risk of breakthrough infections compared to wild-type (WT) virus in kidney transplant recipients (KTRs). The…
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