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Articles tagged "Vaccination"

  • 2020 American Transplant Congress

    Improving Vaccination Rates for Influenza and Pneumococcal Disease in Pediatric Kidney Transplant Recipients

    A. M. McGrath1, J. Baquir1, L. Maestretti1, G. James1, K. DiNello1, M. Patton1, A. Fong1, A. Gallo2, V. Sigurjonsdottir2, P. Grimm2, A. Chaudhuri2

    1Pediatric Kidney Transplant, Lucile Packard Children's Hospital Stanford, Palo Alto, CA, 2Pediatric Kidney Transplant, Stanford University, Palo Alto, CA

    *Purpose: Pediatric renal transplant recipients are highly vulnerable to infections caused by influenza and pneumococcus and vaccines are recommended in this population. At our center,…
  • 2020 American Transplant Congress

    Incidence and Effects of Posttransplant Herpes Zoster in Adult Solid Organ Transplant Recipients : A Meta-Analysis

    S. H. Han, D. Kwon

    Yonsei University Health System, Seoul, Korea, Republic of

    *Purpose: Recently, non-live recombinant subunit HZ vaccine showed highly effective for herpes zoster (HZ) in hematopoietic stem cell transplantation. Several observational studies reported various features…
  • 2020 American Transplant Congress

    Vaccine Safety Concerns and Relationship to Comfort with Provider Communication in a Population of Inner-City Kidney Transplant Recipients

    T. Morancy, I. Nadeem, G. Cordero, D. Lee, M. Markell

    SUNY Downstate Medical Center, Brooklyn, NY

    *Purpose: Misperceptions and incorrect beliefs among patients may contribute to patient refusal of vaccines. We examined beliefs and sources of information in a population of…
  • 2020 American Transplant Congress

    Risk Factors for Losing Varicella Immunity after Pediatric Kidney Transplantation

    H. Pizzo1, J. Mirocha2, J. Garrison1, P. R. Soni3, S. Nadipuram3, D. Puliyanda1

    1Pediatric Nephrology, Cedars-Sinai Medical Center, Los Angeles, CA, 2Biostatistics Core, Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, 3Pediatric Infectious Disease, Cedars-Sinai Medical Center, Los Angeles, CA

    *Purpose: Vaccination against varicella zoster (VZV) pre-kidney transplant (kid tx) can help prevent severe disseminated VZV disease in immunosuppressed patients (pts) post-tx. Despite confirmation of…
  • 2020 American Transplant Congress

    Evaluation of Pretransplant Serologies and Vaccination Rates in Kidney Transplant Candidates

    S. Schneider, C. Truax, A. Carlson, B. Clark, B. Sirandas, L. Smith

    Department of Pharmacy Services, University of Utah Health, Salt Lake City, UT

    *Purpose: Assessing serologic status presents opportunities to provide live vaccinations to solid organ transplant (SOT) candidates. This is especially important given the increased risk of…
  • 2020 American Transplant Congress

    HLA-Antibody Develops Preferentially in Healthy Subjects with a T-bethiB Cell Response to Vaccine

    A. Nellore, G. R. Martens, J. T. Killian, J. Houp, E. Zumaquero, B. Mousseau, J. Bradley, F. Zhou, P. A. Goepfert, F. E. Lund

    University of Alabama, Birmingham, AL

    *Purpose: Bystander B cell differentiation into antibody (Ab) secreting cells (ASCs) may augment alloimmunity in the HLA-sensitized patient. Recently, a population of FcrL5+IgDnegB cells that…
  • 2020 American Transplant Congress

    DEPTOR Expression within CD4+Foxp3+ T Regulatory Cells is Crucial for B Cell Activation Responses and Immunoregulation

    J. Wedel1, M. Maslyar1, S. Kong1, M. Laplante2, D. M. Briscoe1

    1Boston Children's Hospital, Boston, MA, 2Lavel University, Quebec, QC, Canada

    *Purpose: We have previously reported that the intracellular protein DEPTOR stabilizes Foxp3 expression, enhances suppressive Treg function and inhibits Treg dedifferentiation. Overexpression of DEPTOR within…
  • 2020 American Transplant Congress

    Direct Acting Anti-Viral Prophylaxis to Prevent Virus Transmission from Hepatitis C Viremic Donors to Hepatitis C Negative Kideney Transplant Recipients

    G. Gupta, I. Yakubu, D. Kumar, I. Moinuddin, L. Kamal, A. King, C. Bhati, A. Sharma, A. Cotterell, A. Khan, M. Levy, R. Sterling

    Virginia Commonwealth University, Richmond, VA

    *Purpose: Previous trials in kidney transplantation (KT) have described a 12-week course of direct-acting anti-viral drugs (DAA) to treat HCV transmission from infected donors to…
  • 2020 American Transplant Congress

    Use of Subunit Herpes Zoster Vaccine in VZV-Seronegative Transplant Recipients to Prevent Primary Varicella

    A. G. L'Huillier1, V. H. Ferreira2, C. Hirzel3, M. Ierullo2, T. Ku2, N. Selzner2, J. Schiff2, J. Tikkanen2, C. Miao4, D. S. Schmid4, A. Humar2, D. Kumar2

    1HUG, Geneva, Switzerland, 2UHN, Toronto, ON, Canada, 3Inselspital, Bern, Switzerland, 4CDC, Atlanta, GA

    *Purpose: Varicella-zoster virus (VZV) primary infection can be prevented by using the live varicella vaccine. However, this is contraindicated after organ transplant. We investigated the…
  • 2020 American Transplant Congress

    Safety and Immunogenicity of Adjuvanted Recombinant Subunit Herpes Zoster Vaccine in Lung Transplant Recipients

    C. Hirzel1, V. H. Ferreira1, A. G. L’Huillier1, T. Ku1, M. Ierullo1, C. Miao2, D. S. Schmid2, J. Tikkanen1, L. G. Singer1, A. Humar1, D. Kumar1

    1University Health Network, Toronto, ON, Canada, 2CDC, Atlanta, GA

    *Purpose: The new adjuvanted subunit recombinant herpes zoster vaccine (RZV; Shingrix™) may have potential utility in transplant patients for the prevention of shingles, but there…
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