ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Articles tagged "Tolerance"

  • 2015 American Transplant Congress

    Effects of Heart and Lung Co-Transplantation Across a Full MHC Barrier in Miniature Swine

    M. Madariaga, P. Spencer, S. Michel, G. La Muraglia II, M. O'Neil, E. Mannon, C. Leblang, I. Rosales, R. Colvin, D. Sachs, J. Allan, J. Madsen.

    Transplantation Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

    Background: We have previously shown that tolerance of heart allografts across a full MHC barrier can be induced in miniature swine after a 12-day course…
  • 2015 American Transplant Congress

    The Role of Skin-Specific Immunobiology and Major Histocompatibility Complex Sharing in Vascularized Composite Allograft Tolerance

    D. Leonard, K. Shanmugarajah, H. Powell, A. Albritton, C. Mallard, D. Sachs, C. Cetrulo, Jr., J. Kurtz.

    Transplantation Biology Research Center, Massachusetts General Hospital, Boston, MA.

    Background: We have developed a reproducible model for induction of tolerance of all components of VCAs across haploidentical MHC barriers in miniature swine. The purpose…
  • 2015 American Transplant Congress

    Stable and Unstable Chimerism During Immunosuppressive Drug Withdrawal in Tolerant Recipients of HLA Matched Combined Kidney and Hematopoietic Cell Transplants

    T. Pham,1 S. Busque,1 J. Scandling,2 J. Shizuru,2 S. Asha,1 S. Strober.2

    1Surgery, Stanford University, Palo Alto, CA; 2Medicine, Stanford University, Palo Alto, CA.

    Our previous studies showed that 75-80% of HLA matched recipients of combined kidney and hematopoietic cell transplants conditioned with total lymphoid irradiation (TLI) and anti-thymocyte…
  • 2015 American Transplant Congress

    Myeloid Cells as a Key Mediator for Impairment of Transplant Tolerance by CMV Infection

    L. Zhang,1 X. Zhang,2 H. Kang,1 X.-F. Liu,2 S. Yan,2 J.-J. Wang,2 M. Abecassis,2 Z. Zhang,2 M. Hummel,2 X. Luo.1,2

    1Medicine, Northwestern University Feinberg school of Medicine, Chicago, IL; 2Comprehensive Transplant Center, Northwestern University Feinberg School of Medicine, Chicago, IL.

    Cytomegalovirus (CMV) is a ubiquitous virus that presents a significant risk for reactivation or de novo infection in transplant recipients. Clinical transplant tolerance has recently…
  • 2015 American Transplant Congress

    Human Adipose Derived Mesenchymal Stem Cells Enhance Bone Marrow Engraftment and Induce Immunological Tolerance

    R. Saidi,2 B. Rajeshkumar,1 P. Agrawal,1 M. Rashighi.1

    1UMASS, Worcester; 2Alpert Medical School of Brown University, Providence.

    Organ transplantation currently requires long-term immunosuppression. This is associated with multiple complications including infection, malignancy and other toxicities. Immunologic tolerance is considered the optimal solution…
  • 2015 American Transplant Congress

    Immunomodulatory Strategies Directed Towards Tolerance of Vascularized Composite Allografts

    M. Madariaga, K. Shanmugarajah, S. Michel, V. Villani, G. La Muraglia II, R. Torabi, D. Leonard, M. Randolph, R. Colvin, K. Yamada, J. Madsen, C. Cetrulo, Jr., D. Sachs.

    Transplantation Biology Research Center, Massachusetts General Hospital and Harvard Medical School, Boston, MA.

    Background: Achieving tolerance of vascularized composite allografts (VCAs) would improve the risk-to-benefit ratio in patients who undergo this life-enhancing transplant. Kidney co-transplantation along with a…
  • 2015 American Transplant Congress

    Six Year Follow-Up of a Phase 2 Clinical Trial to Induce Tolerance in Mismatched Living Donor Renal Transplant Recipients

    J. Leventhal, M. Abecassis, L. Gallon, J. Galvin, J. Mehta, K. Ravindra, D. Tollerud, M. Elliott, S. Ildstad.

    Comprehensive Transplant Center, Northwestern Memorial Hospital, Chicago, IL; Duke University, Durham, NC; Institute for Cellular Therapeutics, University of Louisville, Louisville, KY; Regenerex, LLC, Louisville, KY.

    27 subjects have been transplanted in a phase 2 protocol (IDE 13947) based upon tolerogenic CD8+/TCR- facilitating cells (FCRx) and 200 cGy TBI-based nonmyeloablative conditioning…
  • 2015 American Transplant Congress

    Vaccine-Induced 'Incognito' CD8+ T Cell Memory Can Disrupt Transplantation Tolerance

    M. Nelsen,1 K. Beard,2 R. Kedl,1 R. Gill.2

    1Dept of Immunology & Microbiology, Univ of Colorado, Aurora, CO; 2Dept of Surgery, Univ of Colorado, Aurora, CO.

    Transplant recipients harbor immunity to vaccines and pathogens (e.g. CMV, EBV). Pre-existing immunity can have significant antigen-specific ramifications, usually attributed to heterologous immunity, as pathogen-reactive…
  • 2015 American Transplant Congress

    Glycogen Synthase Kinase 3β Inhibition Promotes Human iTreg Differentiation and Suppressive Function

    Y. Xia, H. Zhuo, Y. Lu, L. Deng, R. Jiang, L. Zhang, L. Pu, X. Wang.

    The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.

    Induced regulatory T cells (iTregs) are essential to maintain immunological tolerance, immune homeostasis, and prevention of autoimmunity. Some studies suggest that glycogen synthase kinase 3β…
  • 2015 American Transplant Congress

    Costimulation Blockade Prevents Rejection of Vascularized Composite Allografts

    B. Oh,1 G. Furtmüller,1 M. Fryer,1 J. Grahammer,2 S. Schneeberger,2 D. Cooney,1 W. Lee,1 G. Brandacher.1

    1Department of Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, MD; 2Department of Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, Innsbruck, Austria.

    [Background] Vascularized composite allotransplantation (VCA) is an emerging new era in transplant medicine and has become a valid therapeutic option after devastating tissue loss. The…
  • « Previous Page
  • 1
  • …
  • 49
  • 50
  • 51
  • 52
  • 53
  • …
  • 57
  • Next Page »

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences