ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2022 American Transplant Congress
    • 2021 American Transplant Congress
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2021 Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Search

Articles tagged "T cell graft infiltration"

  • 2022 American Transplant Congress

    Human PBMC-Transferred Murine MHC Class I/II-Deficient NOG Mice Enable Long-Term Evaluation of Human Immune Responses to Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Sheets

    R. Matsumoto

    Center for Immune Therapeutics and Diagnosis, Juntendo University, Tokyo, Japan

    *Purpose: Transplantation of cardiomyocytes sheets derived from allogenic human induced pluripotent stem cells (hiPS-CMs) hold great promise in generating new functional myocardium in situ. However,…
  • 2022 American Transplant Congress

    Novel Role of CD74 in Regulatory T Cell Homeostasis and Function in Allo-Immune Response

    Z. Solhjou1, H. Zhang1, N. Younis1, J. Choi1, C. Deban1, A. Saad1, A. Halawi1, Z. Jing1, R. Bucala2, J. Azzi1

    1Brigham and Women's Hospital, Boston, MA, 2Yale University School of Medicine, New Haven, CT

    *Purpose: Identifying new molecular targets based on our understanding of the biology of the allo-immune response in the allograft microenvironment is critical to develop more…
  • 2022 American Transplant Congress

    Gene Profiling to Distinguish Mechanisms of Liver Allograft Rejection and Acceptance in Cynomolgus Monkey

    H. Sakai1, E. Berglund1, S. Chaudhry1, Y. Kato1, E. Duggan1, J. Weiner1, P. Alonso-Guallart1, N. Llore1, K. Brustle1, J. Stern1, B. Piegari1, D. Ekanayake-Alper1, M. Martinez2, G. Pierre1, M. Danton1, S. Kofman1, D. Ordanes1, D. Hajosi1, J. Lefkowitch3, A. Iuga1, T. Kato4, A. Griesemer1

    1Columbia Center for Translational Immunology, Columbia University, New York, NY, 2Department of Pediatrics, Columbia University, New York, NY, 3Departments of Pathology and Cell Biology, Columbia University, New York, NY, 4Department of Surgery, Columbia University, New York, NY

    *Purpose: Liver is an immune regulatory organ. Spontaneous resolutions from rejection have been seen in our orthotopic cynomolgus monkey liver transplant models for tolerance induction…
  • 2021 American Transplant Congress

    Utility of Follow-up Biopsies After Acute Rejection in Pediatric Kidney Transplantation

    S. S. Raza1, V. Hauptfeld-Dolejsek1, F. Rosenblum1, E. C. Mroczek-Musulman2, D. R. Kelly2, M. Seifert1

    1Department of Nephrology, UAB School of Medicine, Birmingham, AL, 2Children’s of Alabama, Birmingham, AL

    *Purpose: Treatment of acute kidney transplant rejection in children is often guided by creatinine-based estimates of GFR (eGFR) that may lack sensitivity to determine the…
  • 2021 American Transplant Congress

    Anti-CD8 Immuno-PET for Non-invasive Tracking of Early Graft Rejection in a Non-human Primate Kidney Transplant Model

    K. Bruestle1, R. Tavare2, F. Fredriksson1, E. Duggan1, F. Huang1, B. Bhola1, J. Giurleo2, R. Foster2, P. Krueger2, M. Dobosz2, D. Ekanayake-Alper1, H. Sakai1, B. Piegari1, J. Castrillion1, S. M. Coley1, O. Harari2, A. Mintz1, D. Ma2, A. Griesemer1

    1Columbia University Medical Center, New York City, NY, 2Regeneron Pharmaceuticals, Inc, New York City, NY

    *Purpose: Infiltration of CD8 T cells into solid organ grafts is an early sign of rejection. REGN5054 is a fully human monoclonal antibody that binds…
  • 2021 American Transplant Congress

    Quilty Lesions are Associated with a Tolerance Profile in Heart Allografts Biopsies

    J. Torrealba, S. Moore, S. Sathirareuangchai, L. De Las Casas, Q. Cai

    Pathology, UTSW Medical Ctr, Dallas, TX

    *Purpose: Previously, in 42 cardiac allograft biopsies, we demonstrated that the presence of Foxp3+ innate and TGF- β + adaptive regulatory lymphocytes in Quilty lesions…
  • 2021 American Transplant Congress

    The Effect of the Different Donor-Derived HLA T-Cell Epitope Targets on the Development of T Cell-Mediated Rejection After Kidney Transplantation

    A. Senev, E. Van Loon, M. Emonds, M. Naesens

    Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium

    *Purpose: Many kidney allografts fail due to rejections caused by the donor and recipient HLA incompatibility. Recent studies have shown that HLA-DR and DQ mismatches…
  • 2021 American Transplant Congress

    P40 Homodimers Induce Il-15 to Promote Endogenous Donor-reactive Memory Cd8 T Cell Activation within High-risk Cardiac Allografts

    H. Tsuda, A. Valujskikh, R. Fairchild

    Inflammation and Immunity, Cleveland Clinic, Cleveland, OH

    *Purpose: Longer cold ischemic storage (CIS) time prior to transplant results in increased proliferation of endogenous donor-reactive memory CD8 T cells within complete MHC-mismatched cardiac…
  • 2021 American Transplant Congress

    Dynamic Reconstitution of Recipient Resident Memory T Cell Repertoire After Human Intestinal Transplantation

    W. Jiao, M. Martinez, J. Zuber, A. Obradovic, R. Jones, E. Waffarn, Z. Wang, A. Gorur, K. Rogers, T. Kato, Y. Shen, J. Fu, M. Sykes

    Columbia University, New York, NY

    *Purpose: Our studies in intestinal transplant (ITx) recipients demonstrated that donor T cell blood macrochimerism(peak level ≥4%) is associated with slower graft T cell replacement…
  • 2020 American Transplant Congress

    CD11b is a Novel Alternate Receptor for CD154 During Alloimmunity

    M. L. Ford, D. Liu

    Emory University, Atlanta, GA

    *Purpose: For decades, blockade of CD40-CD154 has been shown to be a highly effective means of inhibiting alloreactive T cell responses and inducing long-term graft…
  • « Previous Page
  • 1
  • 2
  • 3
  • 4
  • …
  • 7
  • Next Page »

Visit Our Partner Sites

American Transplant Congress (ATC)

Visit the official site for the American Transplant Congress »

American Journal of Transplantation

The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

American Society of Transplantation (AST)

An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

American Society of Transplant Surgeons (ASTS)

The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

Copyright © 2013-2025 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

Privacy Policy | Terms of Use | Cookie Preferences