ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Sensitization"

  • 2019 American Transplant Congress

    Single Center Deceased Donor Renal Transplant (DDRTx) Outcomes in Sensitized Patients after Implementation of the Kidney Allocation System (KAS)

    S. S. Patel, K. L. King, J. Kamal, E. Vasilescu, A. Husain, S. Mohan, L. E. Ratner, R. Crew

    Columbia University Irving Medical Center, New York, NY

    *Purpose: Introduction of KAS in 2014 prioritized access to DDRTx for highly-sensitized candidates although it was unclear whether the outcomes would be acceptable in this…
  • 2019 American Transplant Congress

    Transplantation of the Highly Sensitized Renal Transplant Candidate in the Post-KAS Era: Who is Left Out?

    C. Schinstock, B. Smith, A. Bentall, M. Stegall

    Mayo Clinic, Rochester, MN

    *Purpose: Highly sensitized kidney transplant candidates are given high priority under the new kidney allocation system (KAS), but it is unclear if all sensitized candidates…
  • 2019 American Transplant Congress

    Could Intravenous Iron Strengthen The Chances Of Heart Transplantation For Patients With Left Ventricular Assist Devices?

    A. Mardis1, C. Mardis2, J. Barham3, A. Poole3, S. Branham3, R. Napier4, J. Martin3, P. McCann4

    1Department of Pharmacy, Palmetto Health, Columbia, SC, 2Clinical Pharmacy and Outcomes Sciences, University of South Carolina, Columbia, SC, 3Cardiothoracic Surgery, Palmetto Health, Columbia, SC, 4Cardiology, Palmetto Health, Columbia, SC

    *Purpose: Iron deficiency anemia (IDA) is prevalent in patients supported by left ventricular assist devices (LVADs), is associated with functional limitations, and often warrants blood…
  • 2019 American Transplant Congress

    Long-Term Outcomes of Eculizumab-Treated Positive Crossmatch Recipients: Allograft Survival, Histologic Findings, and Natural History of the Donor-Specific Antibodies

    C. Schinstock, A. Bentall, S. Byron, L. Cornell, M. Everly, M. Gandhi, M. Stegall

    Mayo Clinic, Rochester, MN

    *Purpose: We aimed to determine long-term outcomes for eculizumab-treated, positive crossmatch (+XM) kidney transplant recipients as compared with +XM and age-matched negative crossmatch (−XM) control…
  • 2019 American Transplant Congress

    Alemtuzumab versus Antithymocyte Globulin Induction Immunosuppression in Highly Sensitized Kidney Transplant Recipients

    A. Brueckner1, E. Yanqui1, C. Truong1, R. Baliga2, L. Bowman1

    1Tampa General Hospital, Tampa, FL, 2Florida Kidney Physicians, Tampa, FL

    *Purpose: Lymphocyte depleting agents such as rabbit anti-thymocyte globulin (rATG) and alemtuzumab are used for induction in highly sensitized (PRA ≥30%) kidney transplant recipients (KTRs).…
  • 2018 American Transplant Congress

    Mid-Term Outcome of Donor Specific Antibody Positive Deceased Donor Kidney Transplantation with Peri-Transplant Desensitization

    K. Osickova,1 P. Hruba,2 J. Slatinska,1 A. Slavcev,2 J. Fronek,2 E. Honsova,2 O. Viklicky.1

    1Dept. of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic; 2Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

    Donor specific HLA-antibodies (DSA) remain a large barrier to successful kidney transplantation and there is a limited knowledge about desensitization strategies in deceased donor programs.Anti…
  • 2018 American Transplant Congress

    Desensitization to Facilitate Matching in a Large, National Kidney Paired Exchange Clearinghouse

    C. Holscher,1 A. Thomas,1 K. Jackson,1 C. Haugen,1 M. Ronin,2 A. Waterman,3,4 A. Massie,1,5 J. Garonzik Wang,1 D. Segev.1,5

    1Johns Hopkins School of Medicine, Baltimore; 2National Kidney Registry, New York; 3David Geffen School of Medicine at UCLA, Los Angeles; 4Terasaki Research Institute, Los Angeles; 5Johns Hopkins School of Public Health, Baltimore.

    In kidney paired exchange (KPE) programs, the use of incompatible transplantation has been necessary to prevent long waiting times for sensitized candidates and to facilitate…
  • 2018 American Transplant Congress

    Heart Transplant across Low or Moderate Level Donor-Specific Antibodies Have Acceptable Outcome

    M. Olymbios, J. Patel, R. Levine, S. Dimbil, M. Kittleson, M. Rafiei, X. Zhang, J. Kobashigawa.

    Cedars Sinai Medical Center, Los Angeles.

    Purpose: The presence of pre-transplant donor specific antibodies (DSA) can reduce the likelihood of a patient (pt) obtaining a compatible donor heart. The proportion of…
  • 2018 American Transplant Congress

    Assessing Response to Desensitization: What Makes Sense?

    E. Kransdorf, J. Patel, M. Kittleson, R. Levine, S. Dimbil, D. Geft, D. Chang, L. Czer, J. Kobashigawa.

    Cedars Sinai Medical Center, Los Angeles.

    Purpose: Sensitized candidates experience prolonged waiting times for heart transplant (HT). Desensitization therapies can increase access to HT for sensitized candidates, but changes in calculated…
  • 2018 American Transplant Congress

    What Threshold MFI is the Luminex 1:8 Dilution the Poor Man's C1q for Patients Awaiting Heart Transplant?

    M. Kittleson, J. Patel, E. Kransdorf, R. Levine, S. Dimbil, D. Geft, D. Chang, L. Czer, J. Kobashigawa.

    Cedars Sinai Medical Center, Los Angeles.

    Purpose: Heart transplant candidates are evaluated for anti-HLA antibodies by Luminex single-antigen bead testing to avoid donors that may harbor antigens that these antibodies are…
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