2015 American Transplant Congress
Characterization of Peripheral Blood T and B Cells of Sensitized Kidney Transplant Recipients With Long Term Stable Graft Function
We examined the phenotype of T and B cells of peripheral blood of sensitized kidney transplant recipients with stable graft function (GFR > 29mL/min) enrolled…2015 American Transplant Congress
Eculizumab as a Rescue Therapy for Rhinovirus-Induced Antibody Mediated Rejection After Incompatible Kidney Transplantation
Northwestern University, Chicago, IL.
Background: Despite being an effective strategy for overcoming ABO and HLA incompatibilities, desensitized kidney transplantation still has limitations. Early antibody mediated rejection (ABMR) may be…2015 American Transplant Congress
CPRA Values Are Substantially Increased for Some Candidates Subsequent to Inclusion of Unacceptable C-locus (UA-C) Antigens While Listing Practices Remain Unchanged
1UNOS, Richmond; 2Emory University Hospital, Atlanta; 3Stanford University, Palo Alto.
Background: CPRA is the % of deceased donors expected to have one or more UAs with a given candidate. Prior to 12/5/13, candidates with UA-C…2015 American Transplant Congress
Post-Kidney Allograft Nephrectomy Anti-HLA Immunization Is Not Due to a Release of Anti-HLA Antibodies from the Failed Kidney
Background and aims: The reasons for the increased incidence of de novo anti-HLA donor specific antibodies (DSAs) that is observed after kidney allograft nephrectomy (NTx)…2015 American Transplant Congress
Cytomegalovirus and BK Infections in Sensitized Kidney Transplant Recipients
Department of Medicine, University of Wisconsin School of Medicine and Pubic Health, Madison.
Background:There is little information on the incidence, risk factors and outcomes associated with cytomegalovirus (CMV) and BK infections in sensitized patientsMethods:We examined 254 kidney transplant…2015 American Transplant Congress
What Can UNOS Data Tell Us About Patient Outcomes After Primary Renal Allograft Failure?
Evidence based approaches to patient care after Renal Allograft Failure do not exist, despite this being a high mortality period. Access to retransplantation is important…2015 American Transplant Congress
Left Ventricular Assist Device–Associated Allosensitization — Clinical Implications
U.T.A.H. Cardiac Transplant Program, Salt Lake City, UT.
Purpose: Allosensitization has been recognized as a prognostic marker of worse outcome after transplant. It is unclear, however, whether sensitization events that take place shortly…2015 American Transplant Congress
Are DQA Antibodies Real?
Medicine, Johns Hopkins University School of Medicine, Baltimore, MD.
Antibodies specific for HLA-DQ antigens appear to be increasing in frequency in the post-transplant period and are difficult to reduce effectively with desensitization protocols using…2015 American Transplant Congress
Desensitization With Costimulation Blockade and Proteasome Inhibition in a Non-Human Primate Model of Kidney Transplantation
[Background] Sensitization is a growing problem on the kidney waiting list. Alloantibody can significantly deteriorate graft survival. Currently used desensitization strategies are time-consuming, expensive and…2015 American Transplant Congress
MHC-Class-II Specific Sensitization in a Non-Human Primate Model of Sensitzation
1Emory University, Atlanta, GA; 2Medical University Vienna, Vienna, Austria.
[Background] Sensitization before transplantation and de novo alloantibodies affect a significant number of patients awaiting kidney transplantation. The type of anti-HLA antibody varies with subgroups…
American Transplant Congress abstracts