ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Sensitization"

  • 2016 American Transplant Congress

    Pregnancy Excludes Women from Successful Living Donor Transplantation.

    P. Porrett,1 B. Bromberger,2 S. Hashmi,1 A. Morrison,1 D. Sawinski.3

    1Surgery, University of Pennsylvania, Philadelphia, PA; 2Surgery, Columbia University, New York, NY; 3Medicine, University of Pennsylvania, Philadelphia, PA.

    INTRODUCTION Pregnancy-induced sensitization (PIS) is a barrier to the transplantation of women and contributes significantly to gender disparity in transplantation. We hypothesized that this barrier…
  • 2016 American Transplant Congress

    Bone Allograft: An Unusual Cause of Sensitization.

    J. Bloch,1 V. Elsermans,2 F. Provôt,1 A. Lionet,1 L. Wajbrot-Houzé,3 C. Noel,1 M. Hazzan.1

    1Service de Néphologie et Transplantation, CHRU, Hopital Claude Huriez, Lille, France; 2Institut d'Immunologie, CHRU, Centre de Biologie et Pathologie, Lille, France; 3Service de Néphrologie, Centre Hospitalier de Béthune, Béthune, France.

    We report the case of a 33 year-old female patient who started hemodialysis in 2009 because of end stage renal disease of unknown etiology. When…
  • 2016 American Transplant Congress

    Activation of Alloreactive T Cells by Allogeneic Exosomes and Cells Cross-Dressed with Allogeneic MHC Molecules.

    M. Babiker-Mohamed, J. Marino, P. Crosby, G. Benichou.

    Department of Surgery, Center for Transplantation Sciences, Massachusetts General Hospital & Harvard Medical School, Boston, MA.

    Our recent studies have documented the presence of high numbers of recipient antigen presenting cells (APCs) displaying donor MHC molecules (cross-dressed) on their surface after…
  • 2015 American Transplant Congress

    The Differential Effect of HLA-DQ Mismatching on Renal Allograft Survival in Zero HLA-A,B,DR Mismatched Deceased Donor Transplants

    M. Casey,1 X. Wen,1 S. Rehman,1 A. Santos,1 S. Goldstein,1 K. Andreoni,1 B. Kaplan,2 K. Womer.1

    1University of Florida, Gainesville; 2University of Kansas, Kansas City.

    The role of HLA-DQ matching in renal graft survival is not well understood and difficult to interpret in the presence of other HLA antigen mismatches.…
  • 2015 American Transplant Congress

    Kidney Vs. Heart Calculated PRA (CPRA) for Sensitized Heart Candidates: Does Donor Ethnic Distribution Make a Difference?

    A. Kucheryavaya, L. Robbins Callahan, L. Edwards.

    UNOS, Richmond.

    Background: CPRA, which is used for deceased donor (DD) kidney (KI) and pancreas/kidney-pancreas (PA/KP) allocation, is computed with KI DD HLA and ethnic frequencies. CPRA…
  • 2015 American Transplant Congress

    Does the C1q Assay Predict the Result of Lymphocyte Flow Cross-Match (FCxM) in Potential Renal Transplant Recipients With HLA-DSA and AHG-CDC CxM negative?

    J. Arreola-Guerra, A. de Santiago, A. Arvizu, N. Gonzalez-Tableros, M. Lopez, M. Vilatoba, L. Morales-Buenrostro, J. Alberu, N. Castelan.

    1Transplantation, 1aNephrology-Mineral Metabolism, Inst Nal de Ciencias Medicas y Nutricion SZ, Mexico City, Mexico.

    Background. The presence of pre-transplant HLA donor specific antibodies (DSA) is a recognized risk factor for acute rejection. However, due to the test's (LUMINEX) high…
  • 2015 American Transplant Congress

    Anti-Thymocyte Globulin Induction in Infected Mechanical Circulatory Support Patients: Is It Safe?

    G. Jamero, J. Moriguchi, L. Czer, M. Kittleson, S. Siddiqui, F. Liou, D. Arman, L. Lam, D. Chang, P. Zakowski, J. Kobashigawa.

    Cedars-Sinai Heart Institute, Los Angeles, CA.

    Purpose: The use of mechanical circulatory assist devices (MCSD) have been increasing over the past several years. Driveline infections (DLI) are one of the most…
  • 2015 American Transplant Congress

    Impact of HLA Antibody Monitoring After Kidney Transplantation

    S. Rao,1 M. Ghanta,1 H. Parekh,2 A. Gillespie,1 I. Lee,1 S. Geier,2 K. Lau,3 S. Karhadkar,3 A. Di Carlo,3 S. Constantinescu.1

    1Nephrology, Temple Univesity School of Medicine, Philadelphia, PA; 2Pathology, Temple Univesity School of Medicine, Philadelphia, PA; 3Surgery, Temple Univesity School of Medicine, Philadelphia, PA.

    The impact of donor specific antibodies (DSA) and optimal therapeutic intervention for DSA in kidney transplant (KT) recipients has been reported with variable results. We…
  • 2015 American Transplant Congress

    Outcomes of Simultaneous Pancreas and Kidney Transplantation With a High Level of Preformed Antibodies

    H. Sharma, A. El-Bakry, V. Venkat, S. Papachristos, R. Dhanda, D. Van Dellen, T. Campbell, T. Augustine, R. Pararajasingam, A. Tavakoli, B. Forgacs.

    Transplant Surgery, Manchester Royal Infirmary, Manchester, United Kingdom.

    BACKGROUND:There is paucity of data of outcomes of simultaneous pancreas and kidney transplantation in recipients with preformed antibodies. Newer induction agents have been used with…
  • 2015 American Transplant Congress

    Induction With an Interleukin-2 Receptor Antagonist in Sensitized Adult Kidney Transplant Recipients Is Highly Effective and Safe

    J. Casale, J. Fleming, D. Taber, C. Staino, K. Boyle, K. Covert, N. Pilch, H. Meadows, C. Mardis, K. Chavin, C. Bratton, J. McGillicuddy, P. Baliga.

    MUSC, Charleston, SC.

    Background: The effectiveness and safety of induction with basiliximab (IL2RA) in sensitized kidney transplant recipients is not clearly established. The aim of this study was…
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