2016 American Transplant Congress
Survey Results Show Strong Support for Allowing Patients Undergoing Desensitization to Keep Their Pre-Desensitization CPRA Allocation Priority.
1UNOS, Richmond; 2Emory Univ Hosp, Atlanta; 3Stanford Univ, Palo Alto.
Background: On the waitlist, highly sensitized kidney (KI) candidates who undergo desensitization (DS) lose allocation priority associated with pre-DS CPRA value if some unacceptable antigens…2016 American Transplant Congress
Short UK Dialysis Does Not Significantly Impact on Live Donor Kidney Allograft Survival.
Background. The survival advantage of pre-emptive transplantation (Pre-empTx) in live donor kidney transplantation (LDKTx) was reported by Meier-Kreische (Kidney International, 2000). Dialysis practices differ internationally…2016 American Transplant Congress
Characteristics Independently Associated with Kidney Candidates Having CPRA of 99-100%.
Background: The new Kidney Allocation System (KAS) implemented on 12/4/14 included an increased allocation priority for candidates with CPRA 99-100%. On 11/30/14, just days prior…2016 American Transplant Congress
Pregnancy Excludes Women from Successful Living Donor Transplantation.
INTRODUCTION Pregnancy-induced sensitization (PIS) is a barrier to the transplantation of women and contributes significantly to gender disparity in transplantation. We hypothesized that this barrier…2016 American Transplant Congress
Bone Allograft: An Unusual Cause of Sensitization.
We report the case of a 33 year-old female patient who started hemodialysis in 2009 because of end stage renal disease of unknown etiology. When…2016 American Transplant Congress
Activation of Alloreactive T Cells by Allogeneic Exosomes and Cells Cross-Dressed with Allogeneic MHC Molecules.
Our recent studies have documented the presence of high numbers of recipient antigen presenting cells (APCs) displaying donor MHC molecules (cross-dressed) on their surface after…2016 American Transplant Congress
Limiting Helper Functions of CD4 T Cells Improves Efficacy of Induction Therapy without Compromising Responses to Third Party Antigens.
Antibody mediated lymphocyte depletion is commonly used in clinical transplantation. However, memory T cells undermine the efficacy of lymphoablative induction therapies in sensitized transplant recipients.…2016 American Transplant Congress
Frequency and Utility of Donor-Specific Antibody Testing in Simultaneous Liver Kidney Transplant.
Introduction: The risk of antibody mediated rejection (AMR) in simultaneous liver kidney (SLK) recipients is thought to be lower than in kidney alone patients due…2016 American Transplant Congress
Transplanting the Extremely Sensitized Patient: The University of Wisconsin Experience with the New Kidney Allocation System.
Department of Surgery, Division of Transplantation, University of Wisconsin, Madison, WI.
Background: The new UNOS kidney allocation system (KAS) prioritizes the transplant of highly sensitized patients with a calculated Panel Reactive Antibody (cPRA) ≥80 and extremely…2016 American Transplant Congress
Anti-HLA Antibodies in Allogeneic and Autologous Hematopoietic Stem Cell Transplantation.
Introduction: Anti-HLA antibodies have been associated with graft rejection in solid organ and hematopoietic stem cell transplantation (HSCT). The aim of this study was describe…
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