Articles tagged "Safety"

2022 American Transplant Congress
Impact of Dysgeusia on Transplant Recipients with Refractory Cytomegalovirus with/without Resistance Receiving Maribavir: Post-Hoc Analyses from a Phase 3 Randomized Trial
F. Silveira¹, S. Haider², D. Kaul³, O. Witzke⁴, J. Gu⁵, A. Sundberg⁵
¹Univ. Pittsburgh, Pittsburgh, PA, ²McMaster Univ., Hamilton, ON, Canada, ³Univ. Michigan, Ann Arbor, MI, ⁴Univ. Duisburg-Essen, Essen, Germany, ⁵Takeda Development Center Americas, Inc., Lexington, MA
*Purpose: In a Phase 3 study (SOLSTICE; NCT02931539), maribavir (MBV) was superior to investigator-assigned therapies (IAT; val/ganciclovir, foscarnet, or cidofovir) for CMV clearance at Wk…
2022 American Transplant Congress
Efficacy and Safety of Denosumab on Osteoporosis in Kidney Transplant Recipients
W. Park, J. Kwon, J. Lim, Y. Kim, J. Paek, K. Jin, S. Han
Division of Nephrology, Department of Internal Medicine, Keimyung University School of Medicine, Keimyung University Dongsan Hospital, Daegu, Korea, Republic of
*Purpose: The use of immunosuppressive agents, especially glucocorticoids, are associated with increased risks of bone loss in kidney transplant recipients (KTRs). Denosumab, a potent antiresorptive…
2022 American Transplant Congress
Immunogenicity of a Quadrivalent Human Papillomavirus Vaccine in Pediatric Kidney and Liver Transplant Recipients
T. Kitano¹, K. Schwartz², M. Abdulnoor¹, H. Garfield³, N. K. Booran¹, Y. Avitzur¹, C. Teoh¹, D. Hebert⁴, U. Allen³
¹Hospital for Sick Children, Toronto, ON, Canada, ²Public Health Ontario, Toronto, ON, Canada, ³University of Toronto, Toronto, ON, Canada, ⁴The Hospital for Sick Children, Toronto, ON, Canada
*Purpose: Solid-organ transplant recipients are at increased risk of developing human papillomavirus (HPV)-related diseases. The immunogenicity of HPV vaccine for solid-organ transplant population needs further…
2022 American Transplant Congress
Utilizing Online Training Modules and Flowcharts to Maintain Regulatory Compliance with Abo Verification and Organ Check-In Procedures
L. Adamski¹, S. Ceschini², F. K. Butt³
¹Penn State College of Medicine, Hershey, PA, ²Penn State Milton S. Hershey Medical Center, Hershey, PA, ³Penn State Hershey Milton S Medical Center, Hershey, PA
*Purpose: Meeting the regulatory requirements for ABO Verification and solid Organ Check-In procedures is a constant challenge for transplant programs due to continuous turnover in…
2022 American Transplant Congress
Immunotherapy Before Solid Organ Transplantation: An International Transplant Community-Focused Survey
T. Ivanics¹, M. P. Claasen¹, D. Al-Adra², G. Sapisochin³
¹University of Toronto - University Health Network, Toronto, ON, Canada, ²Division of Transplantation, Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, WI, ³Multi-organ transplant program, University Health Network, Toronto, ON, Canada
*Purpose: The use of immunotherapy for cancer has increased and is expected to continue to grow. The outcomes after solid organ transplantation (SOT) in patients…
2022 American Transplant Congress
Single Center Retrospective Study Examining the Safety of the New Potassium- Binders for Post-Operative Hyperkalemia in Kidney Transplant Recipients
S. Kapoor¹, A. Campbell², Y. Azzi¹, L. E. Liriano-Ward³, T. Shertel⁴, W. Xiao⁵, D. U. Nnani⁶, S. Farghaly¹, S. Yun⁷, E. Akalin¹, M. Ajaimy¹
¹Einstein-Montefiore Transplant Center, Bronx, NY, ²Montefiore Medical Center, Bronx, NY, ³Transplant, Montefiore Medical Center, Bronx, NY, ⁴-, -, AL, ⁵Albert Einstein College of Medicine, Folsom, CA, ⁶Pharmacy, Montefiore Medical Center, Bronx, NY, ⁷Montefiore Medical Center, New York, NY
*Purpose: We aimed to evaluate the safety and efficacy of two potassium-binders (Patiromer and Sodium Zirconium Cyclosilicate (SZC) in early post-transplant hyperkalemia treatment of kidney…
2022 American Transplant Congress
Off-the-Shelf Allogeneic Invariant NKT Cells Are Safe in the Dog and Induce Both Killer and Regulatory Immune Cells
A. Rotolo, E. Whelan, M. Atherton, K. Coker, R. Duran-Struuck, N. Mason
University of Pennsylvania Veterinary School of Medicine, Philadelphia, PA
*Purpose: Allogeneic invariant Natural Killer T cells (allo-iNKT) are attractive for transplant as they prevent graft rejection and maintain anti-tumor/pathogen effects but do not induce…
2021 American Transplant Congress
Beta-lactam Allergies Among Solid Organ Transplant Recipients: Prevalence and Association with Transplant Admission Length of Stay
N. N. Pettit¹, V. Nguyen², C. T. Nguyen¹, A. Lew¹, J. Pisano¹, L. M. Potter¹
¹University of Chicago Medicine, Chicago, IL, ²University of Michigan College of Pharmacy, Ann Arbor, MI
*Purpose: Previous studies have identified that 14-27% of solid organ transplant (SOT) recipients report a beta lactam allergy (BLA). Patients with BLAs often receive less…
2021 American Transplant Congress
Outcomes After Usage of Organs from Deceased Organ Donors with Sepsis – A Single-center Experience
A. Sharma¹, D. Choudhary¹, D. Kenwar¹, S. Singh¹, S. kumar¹, K. jain², N. Bansal³, A. Ravi¹
¹Renal & Pancreas Transplant Surgery, Postgraduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India, ²Anesthesiology, Postgraduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India, ³Transplant Coordinator, Postgraduate Institute of Medical Education and Research, Chandigarh, Chandigarh, India
*Purpose: The deceased Organ Donation rate is around 0.8/million in our nation. There remains a severe shortage of organs worldwide, leading to a trend towards…
2021 American Transplant Congress
Risk of Statin-Related Side Effects in Kidney Transplant Recipients
S. Bae¹, J. Ahn¹, K. Lentine², M. A. Schnitzler², G. Hess³, H. Xiao², D. Segev¹, M. McAdams DeMarco¹
¹Johns Hopkins University, Baltimore, MD, ²Saint Louis University, Saint Louis, MO, ³Drexel University, Philadelphia, PA
*Purpose: Statins are widely used in kidney transplant (KT) recipients for prevention of cardiovascular events. Statins’ safety profile may differ in KT recipients due to…