ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Safety"

  • 2015 American Transplant Congress

    Temporal Increase in the Incidence of Post-Transplantation Lymphoproliferative Disorder in Adult Renal Transplant Recipients: Analysis of 2 US Insurance Administrative Claims Databases

    T. Kou, H.-U. Meier-Kriesche, J. Preston, A. Gomez.

    Bristol-Myers Squibb Company, Princeton, NJ.

    Purpose: Post-transplant lymphoproliferative disorder (PTLD) is a serious complication after kidney transplant. In a prior analysis using Medicare claims database from 1995 to 2003, the…
  • 2015 American Transplant Congress

    Normothermic Machine Perfusion (NMP) on Discarded Human Livers: The First Model in the US

    Q. Liu, A. Nassar, G. Iuppa, D. Urcuyo-Llanes, D. Sexton, T. Okamoto, T. Uso, A. Bennett, W. Baldwin, K. Abu-Elmagd, J. Fung, C. Miller, C. Quintini.

    Cleveland Clinic, Cleveland, OH.

    The benefit of NMP preservation has been reported in a number of animal studies. Herein we describe safety, feasibility and effectiveness of NMP on discarded…
  • 2015 American Transplant Congress

    Pre-Transplant Cardiac Troponin T (cTT) Is a Strong Predictor of Post Kidney Transplant Hospitalizations

    H. Amer, P. Geerdes, T. Fettes, R. Walker, E. Lorenz, F. Cosio.

    The William J von Liebig Center for Transplantation and Clinical Regeneration, Mayo Clinic, Rochester, MN.

    Identifying patients at risk of re-hospitalization will permit improved monitoring and may decrease morbidity.We examined nine objective variables at the time of transplant and their…
  • 2015 American Transplant Congress

    Efficacy and Safety of Three Different Treatment Regimen in De Novo Renal Transplant Patients: Month 48 Follow-Up Results of the HERAKLES Trial

    C. Sommerer,1 K. Budde,1 V. Kliem,1 O. Witzke,1 M. Guba,1 J. Jacobi,1 B. Vogt,3 I. Hauser,1 P. Reinke,1 R. Stahl,1 T. Rath,1 M. Porstner,2 D. Baeumer,2 M. Zeier,1 W. Arns,1 F. Lehner.1

    1Herakles Study Group, Germany; 2Novartis Pharma, Nuremberg, Germany; 3Herakles Study Group, Switzerland.

    Aim: To compare safety and efficacy of 3 different immunosuppressive (IS) regimen 4years after renal transplantation (Tx).Methods: 802 patients (pts) were included in this 1year,…
  • 2015 American Transplant Congress

    Interim Safety Experience in Transplant Patients Treated With Belatacept (Nulojix) in the Post-Approval Setting

    T. Kou, J. Braga, S. Sibabrata, J. Preston, M. Harler, A. Gomez.

    Bristol-Myers Squibb Company, Princeton, NJ.

    Purpose: Belatacept is a selective T-cell costimulation blocker indicated for prophylaxis of organ rejection in adult patients receiving a kidney transplant in combination with basiliximab…
  • 2015 American Transplant Congress

    Interim Results of a Phase 1 Trial of Treg Adoptive Cell Transfer (TRACT) in Living Donor Kidney Transplant Recipients

    J. Leventhal,1 A. LeFever,2 A. Skaro,1 L. Gallon,1 J. Mathew,1 D. Stare,1 I. Konieczna,1 J. He,1 G. Johnson.3

    1Northwestern University, Chicago; 2Northwestern Memorial Hospital, Chicago; 3TRACT Therapeutics Inc., Chicago.

    Therapeutic cell transfer using regulatory T cells (Tregs) in transplant recipients may reduce the need for drug based immunosuppression (IS) and improve long term graft…
  • 2015 American Transplant Congress

    Trends in Transplant Patient Safety Situation Reporting

    T. Daly,1 H. Neil,2 D. Stewart,2 S. Tlusty,2 A. Harper,2 D. Marshman,3 M. Green.4

    1NY-Presbyterian Hosp., New York, NY; 2UNOS, Richmond, VA; 3LifeNet Health, Roanoke, VA; 4Children's Hosp. of Pittsburgh, Pittsburgh, PA.

    Background: The OPTN Operations & Safety Committee is charged with reviewing aggregated, de-identified safety situation data reported through both the UNet Improving Patient Safety (IPS)…
  • 2015 American Transplant Congress

    Role of Universal Decolonization After Kidney Transplant: A Pilot Study

    D. Lee,1 G. Malat,2 N. Law,1 A. Sharma,1 T. Bias,1 K. Ranganna,1 A. Doyle.1

    1Department of Medicine, Drexel University, College of Medicine, Philadelphia, PA; 2Department of Surgery, Drexel University, College of Medicine, Philadelphia, PA.

    IntroductionInfection is a common cause of morbidity and mortality after kidney transplantation. Despite careful pre-transplantation screening of donors and recipients, vaccination, prophylaxis, and antimicrobial use,…
  • 2015 American Transplant Congress

    Establishment of Diabetes Modeling in Common Marmoset

    W. Yuan,1 S. Fukuda,1 T. Inoue,2 D. Chujo,1 H. Okochi,1 E. Sasaki,2 M. Shimoda.1

    1National Center for Global Health and Medicine, Tokyo, Japan; 2Central Institute for Experimental Animals, Kawasaki, Japan.

    Background:Diabetic nonhuman primates (NHPs) are considered as the good models for both diabetes mellitus research and islet transplantation research safely into clinical applications. However, there…
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