ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Safety"

  • 2022 American Transplant Congress

    Safety and Efficacy of Peri-Vaccination Antimetabolite Hold to Augment Third SARS-CoV-2 Vaccine Dose Response in Lung Transplant Recipients

    S. Frey, J. Ruck, J. Alejo, L. Barker, W. Werbel, R. Avery, D. Segev, P. Shah

    Johns Hopkins University School of Medicine, Baltimore, MD

    *Purpose: Lung transplant recipients (LTRs) are less likely than other solid organ transplant recipients (SOTRs) to develop an antibody response to SARS-CoV-2 vaccination. Mycophenolate has…
  • 2022 American Transplant Congress

    Impact of Sub-therapeutic Tacrolimus Troughs at Discharge from Index Admission on Short-Term Outcomes in Kidney Transplant Recipients Receiving Rabbit Anti-Thymocyte Globulin Induction

    X. Liu1, J. Trofe-Clark2, D. Sawinski3, B. Steiner1, S. Sharma1, S. Witek1, T. Fallah2, M. Norris2, C. Sammons2, G. Malat2

    1Pharmacy, Hosp of Univ of Pennsylvania, Philadelphia, PA, 2Penn Transplant Institute and Pharmacy Dept, Hosp of Univ of Pennsylvania, Philadelphia, PA, 3Penn Transplant Institute, Hosp of Univ of Pennsylvania, Philadelphia, PA

    *Purpose: Kidney transplant (KTx) recipients are often discharged with subtherapeutic tacrolimus (TAC) troughs due to short hospital lengths of stay (LOS) for index KTx admissions.…
  • 2022 American Transplant Congress

    Maribavir (MBV) versus Investigator-Assigned Therapy (IAT) for Refractory Cytomegalovirus (CMV) Infection (with or without Resistance) in Solid Organ Transplant (SOT) Recipients: Subgroup Safety Analysis of a Phase 3 Study

    R. M. La Hoz1, D. Florescu2, D. Kumar3, F. Saliba4, J. Gu5, A. Sundberg5

    1Univ. Texas Southwestern Medical Center, Dallas, TX, 2Univ. Nebraska Medical Center, Omaha, NE, 3Univ. Health Network, Toronto, ON, Canada, 4Univ. Paris Saclay, Paris, France, 5Takeda Development Center Americas, Inc., Lexington, MA

    *Purpose: In a Phase 3 study of MBV vs IAT (val/ganciclovir, foscarnet, or cidofovir) for refractory CMV infection (with/without resistance; R/R) in hematopoietic cell transplant…
  • 2022 American Transplant Congress

    Safety and Efficacy of Sodium Glucose Cotransporter-2 Inhibitors in Solid Organ Transplant Recipients

    L. Selznick, J. Contreras, K. Klein, C. Long, R. Hall, S. Bhayana, H. Sweiss

    University Health, San Antonio, TX

    *Purpose: To determine the safety and efficacy of sodium glucose cotransporter-2 inhibitors (SGLT2i) in solid organ transplant.*Methods: This is a retrospective review of adult kidney,…
  • 2022 American Transplant Congress

    Post-Kidney Transplant Valacyclovir versus Valganciclovir for CMV Prophylaxis: A Randomized Controlled Trial

    P. S. Verghese1, A. Matas2, S. Chinnakotla2, M. Evans3, H. Balfour Jr4

    1Univ of Minnesota Pediatric Nephrology, Minneapolis, MN, 2Surgery, University of Minnesota Medical School, Minneapolis, MN, 3Biostatistics, University of Minnesota, Minneapolis, MN, 4Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN

    *Purpose: Valganciclovir (valG) is an effective CMV prophylactic agent post-kidney transplant (KTx) with significant side effects. Valacyclovir (valA) may be effective for CMV prophylaxis with…
  • 2022 American Transplant Congress

    Development of Diagnostic Algorithms for Peri-Operative Error Cause and Effect Analysis in Renal Transplant Surgery

    P. Gogalniceanu1, H. Maple1, G. Papadakis1, P. Chandak1, I. Loukopoulos1, J. Olsburgh1, N. Kessaris1, F. Calder1, N. Sevdalis2, N. Mamode1

    1Guy's and St.Thomas' NHS Foundation Trust, London, United Kingdom, 2King's College London, London, United Kingdom

    *Purpose: Peri-operative safety metadata in transplant surgery remain limited. Lack of standardisation and limited models of failure analysis, as well as non-intuitive error taxonomies, deter…
  • 2022 American Transplant Congress

    Complex Donor Transfer and Organ Procurement Organization Collaboration to Reduce Ischemia Time in Combined Face and Bilateral Hand Transplant

    J. Trilles1, D. Boczar1, B. F. Chaya1, Z. P. Berman1, G. K. Diep1, R. Rodriguez Colon1, D. J. Ceradini1, E. D. Rodriguez1, B. E. Gelb2

    1Hansjörg Wyss Department of Plastic Surgery, NYU Langone Health, New York, NY, 2Transplant Institute, NYU Langone Health, New York, NY

    *Purpose: We present a complex donor transfer protocol that places the donor at the recipient hospital prior to allograft procurement in order to reduce ischemia…
  • 2022 American Transplant Congress

    Changes Of Socioeconomic Status Of Kidney Transplant Recipients And Their Association With Prognosis

    S. Park1, J. Park1, J. Jihoon1, Y. Kim1, Y. Kim2, H. Lee2

    1Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea, Republic of, 2Seoul National University Hospital, Seoul, Korea, Republic of

    *Purpose: Previous studies showed socioeconomic status affect the level of access to and prognosis of kidney transplantation. Further study is warranted to investigate the changes…
  • 2022 American Transplant Congress

    Immunogenicity and Safety of SARS-CoV-2 Vaccines and Breakthrough Infections Among Solid Organ Transplant Recipients: Systematic Review and Meta-Analysis

    A. Villavicencio1, Y. Ebisu2, M. Raja3, A. P. Sanchez-Covarrubias1, S. Anjan3, J. M. Reynolds1, J. Simkins3, J. Camargo3, M. I. Morris3, L. Abbo4, G. Guerra5, Y. Natori6

    1Internal Medicine, University of Miami Miller School of Medicine, Miami, FL, 2Kameda Medical Center, Chiba, Japan, 3University of Miami Miller School of Medicine, Miami, FL, 4University Of Miami Miller School of Medicine, Miami, FL, 5University of Miami Jackson Memorial Hospital, Miami, FL, 6University of Miami, Pinecrest, FL

    *Purpose: The SARS-CoV-2 pandemic has had a significant impact on the field of solid organ transplant(SOT). Immunization against SARS-CoV-2 is globally available since 2021. SOT…
  • 2022 American Transplant Congress

    Safety of Stimulant Use in Heart Transplant Recipients

    K. Callaghan1, M. Norris1, C. Sammons1, T. Fallah1, H. Eldabbas1, X. Liu1, T. Wang2

    1Pharmacy, Hospital of the Univ of Pennsylvania, Philadelphia, PA, 2Cardiovascular Medicine, Hospital of the Univ of Pennsylvania, Philadelphia, PA

    *Purpose: FDA-approved prescribed stimulants are purported to increase risk of cardiovascular (CV) adverse events, particularly arrhythmias and sudden cardiac death. Debate exists regarding the safety…
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