2019 American Transplant Congress
Elevated Urinary Injury Biomarkers in Deceased Donors Are Not Associated with Long-Term Kidney Transplant Outcomes
*Purpose: In the United States, over 90,000 people are on the kidney transplant waiting list and could benefit from more donor organs. Kidneys from deceased-donors…2019 American Transplant Congress
Donor Derived Cell Free DNA (dd-cfDNA) May Aid in the Diagnosis of BK Virus Nephropathy
*Purpose: Between 10% and 30% of renal transplant recipients (KTR) develop BK viremia; with 1-10% of KTR developing BK virus associated nephropathy (BKVAN), accounting for…2018 American Transplant Congress
The Role of Donor-Derived Cell-Free DNA in Identification of Injury in Kidney Allografts with Antibody-Mediated Rejection and De Novo DSA
Objectives: To evaluate the capacity of donor-derived cell-free DNA (dd-cfDNA) in the identification of injury in kidney allografts with antibody-mediated rejection and de novo DSA.Methods:…2018 American Transplant Congress
Peri-Operative Hemoglobin, Blood Transfusion and Delayed Graft Function in Kidney Transplant Recipients
Background: Studies in the non-kidney transplant (KT) literature support an absolute hemoglobin concentration (Hb) threshold of 70 g/L for transfusion, unless otherwise indicated. Some reports…2018 American Transplant Congress
Endothelin-1 Type A Receptor Antibodies Are Associated with Elevated Il-8, Arteritis and Decline in Renal Function in Pediatric Renal Transplant Recipients
1University of California, Los Angeles, Los Angeles, CA; 2Duke University, Durham, NC.
Background: We have recently shown that the non-HLA antibody, AT1R-Ab, is prevalent and associated with poor outcomes in pediatric kidney transplant recipients (KTRs). The prevalence…2018 American Transplant Congress
Clinical Analysis of Impact of Intraoperative Hepatic Blood Inflow on Acute Kidney Injury Following Allogeneic Liver Transplantation
Background Acute kidney injury (AKI) is a major and severe complication following allogeneic liver transplantation and is associated with increased postoperative morbidity and mortality. With…2018 American Transplant Congress
ACEI/ARB Use within One Year of Kidney Transplant is Associated with Less AKI and Graft Loss in Older Recipients
Medical University of South Carolina, Charleston, SC.
As short-term outcomes have improved, optimizing long-term graft survival remains a major focus of transplant programs. Older kidney transplant recipients are particularly vulnerable to acute…2018 American Transplant Congress
The AKI-Predict-Score: A New Prediction Model for Acute Kidney Injury after Liver Transplantation
BackgroundPostoperative acute kidney injury (AKI) is a frequent complication after liver transplantation and associated with impaired survival rates, chronic kidney disease and higher costs. Although…2018 American Transplant Congress
Extra-Renal Effects of Estrogen Receptor-Alpha Mediate Protection from Renal Ischemia-Reperfusion Injury
Introduction: Females exhibit protection from renal ischemia-reperfusion injury (IRI) compared to males in animal models and in human kidneys transplants. Previous experiments have shown that…2018 American Transplant Congress
QPI-1002, a siRNA Targeting p53: Improvement in Outcomes Following Acute Kidney Injury (AKI): Cardiac Surgery to AKI Donors
Background: QPI-1002 has been observed to statistically reduce the incidence, severity and duration of AKI in a large Phase 2 study of AKI following cardiac…
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