ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Renal injury"

  • 2020 American Transplant Congress

    Value of dd-cfDNA When Considering Recipient Ethnicity to Further to Help Risk Stratify Transplant Recipients

    A. Langone1, B. Fischbach2, D. Cohen3

    1Vanderbilt Health, Nashville, TN, 2Baylor Scott & White Health, Fort Worth, TX, 3Columbia University, New York, NY

    *Purpose: Within the modern era of kidney transplantation, African American (AA) transplant recipients continue to experience disproportionately higher rates of allograft loss. A combination of…
  • 2020 American Transplant Congress

    Mir-124/ire-1α Affects Renal Ischemia/Reperfusion Injury by Regulating Endoplasmic Reticulum Stress in Renal Tubularepithelial Cells

    C. Ding, W. Xue

    Department of Renal Transplantation, The First Affiliated Hospital of Xi’an Jiaotong University, Xi'an, China

    *Purpose: In this study, we investigated the protective functions of miR-124 on renal I/R injury both in vivo and in vitro and explored its underlying…
  • 2020 American Transplant Congress

    Delayed Graft Function Predicts High Risk of Allograft Loss Following Living and Deceased Donor Pediatric Kidney Transplantation

    M. MacConmara1, J. Gattineni1, D. Desai1, J. Parekh2, P. Vagefi1, C. S. Hwang1

    1UT Southwestern, Dallas, TX, 2UC San Diego, San Diego, CA

    *Purpose: Pediatric kidney recipients receive high quality living and deceased donor kidneys for transplantation, and as such, these kidneys have a low rate of delayed…
  • 2020 American Transplant Congress

    Perioperative Predictors of Acute Kidney Injury among Liver Transplant Recipients

    R. Berkowitz1, N. Douville2, G. Mentz2, P. Sharma3, C. Sonnenday1

    1Surgery, Michigan Medicine, Ann Arbor, MI, 2Anesthesiology, Michigan Medicine, Ann Arbor, MI, 3Gastroenterology, Michigan Medicine, Ann Arbor, MI

    *Purpose: We examined the perioperative and intraoperative risk factors associated with post-operative acute kidney injury (AKI) at post-op 7 days and 30-day estimated glomerular filtration…
  • 2020 American Transplant Congress

    Intraoperative Oxygen Delivery and Acute Kidney Injury after Liver Transplantation

    W. Kim, H. Lee, H. Yoon, K. Suh

    Anesthesiology and Pain Medicine, Seoul National University Hospital, Seoul, Korea, Republic of

    *Purpose: Although intraoperative hemodynamic variables were reported to be associated with acute kidney injury (AKI) after liver transplantation, the time-dependent association between intraoperative oxygen delivery…
  • 2019 American Transplant Congress

    Reverse Signaling through CD137 Ligand Promotes Tissue Repair after Ischemia-Reperfusion Kidney Injury

    H. R. Cho1, S. Lee2, J. S. Lee3, S. J. Park1, B. Kwon2

    1Ulsan University Hospital, Ulsan, Korea, Republic of, 2Biomedical Research Center, Ulsan University Hospital, Ulsan, Korea, Republic of, 3Department of Internal Medicine, Ulsan University Hospital, Ulsan, Korea, Republic of

    *Purpose: We previously showed that CD137 ligand (CD137L) reverse signaling play a central role in kidney ischemia-reperfusion injury (IRI) by amplifying acute renal injury. In…
  • 2019 American Transplant Congress

    Blood Profiling Reflects a Significant Down-Regulation in Oxidative Phosphorylation Following Renal Transplantation with DCD and AKI Allografts

    S. Walker1, L. Cox2, C. Langefeld2, B. Freedman2, A. Farney2, J. Rogers2, C. Jay2, R. Stratta2, G. Orlando2

    1Wake Forest Institute for Regenerative Medicine, Winston Salem, NC, 2Wake Forest Baptist Medical Center, Winston Salem, NC

    *Purpose: The human kidney transplant (KT) patient provides a unique and compelling in situ model system to study molecular events that underlie graft recovery following…
  • 2019 American Transplant Congress

    Kidney-Intrinsic Innate Immunity and Endoplasmic Reticulum Stress Pathways are Key Determinants of Severity of Ischemia-Reperfusion Injury Following Transplantation

    L. Qiu1, J. Wang1, X. Yeap1, C. Lin1, Y. S. Kanwar2, D. Fang2, M. M. Abecassis1, Z. J. Zhang1

    1Comprehensive Transplant Center, Department of Surgery, Northwestern University, Chicago, IL, 2Department of Pathology, Northwestern University, Chicago, IL

    *Purpose: Ischemia-reperfusion injury (IRI) following kidney transplantation (KTx) frequently leads to delayed graft function and is detrimental to graft longevity. Causes and susceptibilities of KTx…
  • 2019 American Transplant Congress

    Effects of Pretreated Bortezomib on Renal Function after Renal Ischemia – Reperfusion Injury in Mice

    X. Zheng

    Beijing Chaoyang Hospital, Capital Medical University, Beijing, China

    *Purpose: To observe the effects of pretreated bortezomib at different points on renal function and renal histology after renal ischemia-reperfusion injury in mice.*Methods: A mice…
  • 2019 American Transplant Congress

    Elevated Urinary Injury Biomarkers in Deceased Donors Are Not Associated with Long-Term Kidney Transplant Outcomes

    N. Koyawala, I. E. Hall, Y. Jia, S. G. Mansour, P. P. Reese, H. R. Thiessen-Philbrook, E. Akalin, J. S. Bromberg, M. D. Doshi, M. N. Harhay, S. Mohan, T. Muthukumar, B. Schroppel, P. Singh, F. L. Weng, C. R. Parikh

    DDS Consortium, Baltimore, MD

    *Purpose: In the United States, over 90,000 people are on the kidney transplant waiting list and could benefit from more donor organs. Kidneys from deceased-donors…
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