Articles tagged "Renal injury"

2016 American Transplant Congress
Acute Kidney Injury After Liver Transplantation Is Set in Motion Early After Reperfusion of the Liver Graft: A Prospective Cohort Study.
I. Jochmans,¹ N. Meurisse,² D. Monbaliu,¹ J. Pirenne.¹
¹Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium; ²Abdominal Transplant Surgery, University of Liège, Academic Hospital, Liège, Belgium.
Objective: Determine creatinine changes during liver transplantation and risk factors for acute kidney injury (AKI) in a prospective cohort study (NCT01333319).Background Data: AKI, a major…
2016 American Transplant Congress
Acute Kidney Injury (AKI) Associated with Chronic Kidney Disease (CKD) in Paediatric Non-Kidney Transplant Recipients.
C. Williams,^1,2 K. Borges,² T. Banh,² J. Vasilevska-Ristovska,² R. Chanchlani,^1,2 V. Ng,^1,2 A. Dipchand,^1,2 M. Solomon,^1,2 D. Hebert,^1,2 S. Kim,^1,3 B. Astor,⁴ R. Parekh.^1,2,3
¹University of Toronto, Toronto, Canada; ²Hospital for Sick Children, Toronto, Canada; ³University Health Network, Toronto, Canada; ⁴University of Wisconsin, Madison.
Background: Kidney dysfunction is common after solid organ transplantation; however, rates of post-transplant AKI and CKD in children are unknown.Objective: Determine rates of AKI and…
2015 American Transplant Congress
Acute Kidney Injury in the Early Post Kidney Transplant Period: Frequency, Etiology and Significance
B. Kiberd,¹ S. Cimen,¹ K. Tennankore.²
¹Surgery, Dalhousie University, Halifax, NS, Canada; ²Medicine, Dalhousie University, Halifax, NS, Canada.
Acute kidney injury (AKI) post kidney transplant has not been well described using current diagnostic criteria. The frequency and etiology of AKI in the first…
2015 American Transplant Congress
Mitochondrial Hydrogen Sulphide Donor Molecules Are More Effective Against Hypoxic Injury in Renal Tubular Epithelial Cells
G. Aboalsamh,^1,5 M. Saha,² I. Lobb,² J. Grewal,² P. Luke,^1,2,3 M. Wood,⁴ M. Whiteman,⁴ A. Sener.^1,2,3
¹Urology, University of Western Ontario, London, Canada; ²Microbiology and Immunology, University of Western Ontario, London, Canada; ³University of Western Ontario, University of Western Ontario, London, Canada; ⁴Experimental Therapeutics, University of Exeter Medical School, Exeter, England, United Kingdom; ⁵Surgery, King Abdulaziz Medical Center, Jeddah, Saudi Arabia.
Introduction: Ischemia reperfusion injury (IRI) in organ transplant often manifests itself as delayed graft function (DGF). DGF is associated with increased morbidity and deleterious effects…
2015 American Transplant Congress
Proximal Tubular Dysfunction Is Common After the First Year of Kidney Transplantation
G. Ensergueix,¹ J. Allard,¹ F. Saint-Marcoux,² B. Marin,³ S. Bodeau,² J.-C. Aldigier,¹ P. Marquet,² M. Essig.¹
¹Nephrology, Dialysis, Transplantation, University Hospital, Limoges, France; ²Pharmacology, Toxicology, University Hospital, Limoges, France; ³Epidemiology, Biostatistics, Methodology, University Hospital, Limoges, France.
Background: After the initial period of kidney transplantation, the prevalence of proximal tubular dysfunction (PTD) and its consequences are unknown. The aim of this study…
2015 American Transplant Congress
Acute Kidney Injury and Outcome After Cardiac Transplantation
G. Fortrie,¹ O. Manintveld,² K. Caliskan,² M. Betjes.¹
¹Internal Medicine, Div. of Nephrology, Erasmus Medical Center, Rotterdam, Netherlands; ²Cardiology, Erasmus Medical Center, Rotterdam, Netherlands.
Background:Chronic kidney disease (CKD) is a frequently seen complication after cardiac transplantation and is partly explained by the prolonged use of calcineurin inhibitors. However, few…
2015 American Transplant Congress
Is the Pulsatile Kidney Preservation Machine a Vaulable Tool in Evaluating Kidney Suitability from Older Donors After Brain Death?
D. Paredes Zapata,¹ A. Ruiz Arranz,¹ C. Rodriguez Villar,¹ L. Peri Cussi,² A. Alcaraz Asensio,² R. Adalia Bartolome,¹ F. Oppenheimer Salinas.³
¹Donation and Transplant Coordination Section, Hospital Clinic, University of Barcelona, Barcelona, Spain; ²Urology Department, Hospital Clinic, University of Barcelona, Barcelona, Spain; ³Renal Transplant Unit, Hospital Clinic, Barcelona, Spain.
Introduction: Donors after Brain Death (DBD) older than 60 years old, have become 46.8% of our donor activity, with higher Discard Rate (DR). Assessment of…
2015 American Transplant Congress
Gradual Warming Up Perfusion Post Static Cold Storage Reduces Renal Injury
P. Mahboub,^3,1 P. Ottens,¹ R. Ploeg,² P. Martins,³ H. Leuvenink.¹
¹Surgery, UMCG, Groningen, Netherlands; ²Surgery, University of Oxford, Oxford, United Kingdom; ³Surgery, UMass, Worcester, MA.
We hypothesize that the sudden warm reperfusion after Cold Storage [CS] is detrimental for the graft and we therefore evaluated different warming-up procedures before reperfusion.Methods:Rat…
2015 American Transplant Congress
100 Protocol Renal Allograft Biopsies at 10 Years: First Look at the Tacrolimus Era
M. Stegall,¹ W. Park,¹ F. Cosio,² L. Cornell.³
¹Transplant Surgery, Mayo Clinic, Rochester, MN; ²Medicine, Mayo Clinic, Rochester, MN; ³Laboratory Medicine, Mayo Clinic, Rochester, MN.
This study examined late renal allograft injury in the Tacrolimus era in 10-yr protocol biopsies (Bx).Methods One hundred 10-yr protocol allograft bx were assessed using…
2015 American Transplant Congress
Banff Criteria Are Inadequate to Assess Chronic Renal Allograft Injury 10 Years Post-Transplantation
L. Cornell, W. Park, F. Cosio, M. Stegall.
Mayo Clinic, Rochester, MN.
Background: The Banff criteria have been developed to assess acute and chronic injury in renal allografts. However, the criteria have been based on biopsies for…