Articles tagged "Renal failure"

2022 American Transplant Congress
Meta-Analysis of the Chronic Exposure to Calcineurin Inhibitors and the Risk for Chronic and End-Stage Kidney Disease in Non-Renal Solid Organ Transplant Recipients
A. Alvarez Elias¹, M. Riedl¹, D. Stewart², A. Ruco³, P. Bobos³, S. Maharaj⁴, V. Shah⁵, E. Uleryk⁶, C. Teoh¹, R. Parekh¹
¹Hospital for Sick Children, Toronto, ON, Canada, ²Royal Hospital for Children, Glasgow, United Kingdom, ³St. Michael’s Hospital, Toronto, ON, Canada, ⁴University of Toronto, Toronto, ON, Canada, ⁵Mount Sinai Hospital, Toronto, ON, Canada, ⁶E. M. Uleryk Consulting, Toronto, ON, Canada
*Purpose: Calcineurin inhibitors (CNI) are standard of care immunosuppressants among all solid organ transplant (SOT) recipients, and the most common side effect is nephrotoxicity. There…
2022 American Transplant Congress
Dynapenia Among Kidney Transplant Candidates and Recipients in the United States
A. S. Nalatwad¹, X. Chen¹, N. M. Chu¹, S. P. Norman², D. L. Segev¹, M. McAdams-Demarco¹
¹Epidemiology Research Group in Organ Transplantation, Johns Hopkins University School of Medicine, Baltimore, MD, ²Univ of Michigan Medical Ctr, Ann Arbor, MI
*Purpose: Among Kidney Transplant (KT) patients, sarcopenia, loss of muscle mass, is prevalent and has been associated with post-KT mortality. The burden of dynapenia, an…
2021 American Transplant Congress
Impact of Advanced Renal Dysfunction on Post-Transplant Outcomes After Living Donor Liver Transplantation in the United States
T. Bittermann¹, N. Kaur², P. L. Abt¹, K. M. Olthoff¹, J. K. Heimbach³, J. Emamaullee²
¹University of Pennsylvania, Philadelphia, PA, ²University of Southern California, Los Angeles, CA, ³Mayo Clinic College of Medicine, Rochester, MN
*Purpose: Survival after living donor liver transplantation (LDLT) in the U.S. is excellent. However, the significance of pre-transplant kidney disease on outcomes after LDLT is…
2021 American Transplant Congress
Covid-19 in Solid Organ Transplantation (SOT): Results of the National Covid Cohort Collaborative (N3C)
G. Agarwal¹, A. Vinson², R. Dai³, E. French⁴, S. Lee⁵, A. Olex⁴, A. Anzalone⁶, V. Madhira⁷, R. B. Mannon⁸
¹Medicine, University of Alabama at Birmingham, Birmingham, AL, ²Medicine/Nephrology, Nova Scotia Health Authority, Halifax, NS, Canada, ³Biostatistics, University of Nebraska Medical Center, Omaha, NE, ⁴Wright Center for Clinical and Translational Research, VIrginia Commonwealth University, Richmond, VA, ⁵Medicine/Infectious Disease, University of Saskatchewan, Saskatoon, SK, Canada, ⁶Neurology, University of Nebraska Medical Center, Omaha, NE, ⁷Palia Software, Not sure, OR, ⁸Medicine/Nephrology, University of Nebraska Medical Center, Omaha, NE
*Purpose: SARS-CoV-2 infection has resulted in significant mortality in solid organ transplant (SOT) recipients based on reports from single centers or voluntary registries. The N3C…
2021 American Transplant Congress
Outcomes of Transjugular Intrahepatic Portosystemic Shunts (TIPS) in Dialysis-Dependent ESLD Patients: The ALTA Study
J. Ge¹, J. Boike², M. German³, G. J. Morelli⁴, E. Spengler³, A. Said³, A. S. Lee³, A. Hristov³, A. Desai⁵, T. Couri⁶, S. Paul⁶, C. Frenette⁷, N. Christian-Miller⁷, M. Laurito⁸, E. Verna⁸, U. Rahim⁹, A. Goel⁹, D. Gregory², L. VanWagner², K. P. Kolli¹, J. Lai¹
¹University of California, San Francisco, San Francisco, CA, ²Northwestern Memorial Hospital, Chicago, IL, ³University of Wisconsin, Madison, WI, ⁴University of Florida Health, Gainsville, FL, ⁵Indiana University School of Medicine, Indianapolis, IN, ⁶University of Chicago, Chicago, IL, ⁷The Scripps Clinic, La Jolla, CA, ⁸Columbia University, New York, NY, ⁹Stanford University, Stanford, CA
*Purpose: Data on the outcomes of patients with cirrhosis who require renal replacement therapy (RRT) at the time of transjugular intrahepatic portosystemic shunts (TIPS) is…
2021 American Transplant Congress
Mapping Chronic Kidney Disease (CKD) and Acute Kidney Injury (AKI) in Kidney Transplant Biopsies Reveals Two Classes of Early AKI That Differ in Their Response-to-Wounding
P. Halloran¹, J. Reeve¹, G. Böhmig², O. Viklicky³, M. Myslak⁴, G. Gupta⁵, &. the INTERCOMEX Study Group⁶
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²Medical University of Vienna, Vienna, Austria, ³Institute for Clinical and Experimental Medicine, Prague, Czech Republic, ⁴Pomeranian Medical University, Szczecin, Poland, ⁵Virginia Commonwealth University, Richmond, VA, ⁶., ., AB, Canada
*Purpose: We recently analyzed injury-induced molecular changes in kidney transplant biopsies using principal component analysis (PCA) (AJT https://doi.org/10.1111/ajt.16374). PC1 reflected all injury, PC2 distinguished early…
2021 American Transplant Congress
Post-Transplant Idiopathic Immune Complex Glomerulonephritis
F. Aziz, T. Singh, N. Garg, D. Mandelbrot
University of Wisconsin, Madison, WI
*Purpose: The appropriate treatment for post-kidney transplant immune complex glomerulonephritis (ICGN) of unknown cause is unclear.*Methods: From 01/2004 to 12/2018, 71 patients were diagnosed with…
2021 American Transplant Congress
Pre Transplant Estimated Glomerular Filtration Rate and Other Predictors of Mortality and End Stage Kidney Disease After Lung Transplantation
A. Kumar¹, L. N. Bonnell², C. Thomas³
¹Internal Medicine, University of Vermont, Burlington, VT, ²Department of General Internal Medicine Research, University of Vermont, Burlington, VT, ³Internal Medicine, University of Iowa, Iowa City, IA
*Purpose: Lung transplantation is an established treatment for end stage lung disease and as survival has improved, chronic kidney disease (CKD) has become a common…
2021 American Transplant Congress
27 Months Follow Up of a Cohort in the Transplant Continuum After Using a New Electronic Medical Record Tool to Document Transplant Option Discussions Among Patients with EGFR <20 Ml/min/1.73m2
A. A. Yishak¹, M. S. Bhatnagar², A. V. Tomimatsu³, R. La Londe⁴, E. Clark⁵, K. B. Rubenstein⁶, S. Vupputuri⁶
¹MAPMG, McLean, VA, ²Kaiser Permanente |, Oakland, CA, ³Kaiser Permanente, Oakland, CA, ⁴Kaiser Permanente, Oakland,, CA, ⁵Kaiser Permanente, Hyattsville, MD, ⁶MAPRI, Rockville, MD
*Purpose: The purpose of this study was to assess: 1) the documentation of transplant option discussions; 2) the number of members listed & transplanted preemptively;…
2021 American Transplant Congress
A Payer’s Perspective: The Cost of Hemodialysis versus Living Donor Kidney Transplant for Kidney Failure Patients in Nigeria
J. Lang¹, I. James², D. Da Rocha Afodu¹, C. G. Okwuonu³, O. Ekwenna¹
¹University of Toledo College of Medicine and Life Sciences, Toledo, OH, ²Surgical Specialists of Charlotte, Matthews, NC, ³Department of Internal Medicine, Nephrology Unit, Federal Medical Centre, Umuahia, Abia State, Nigeria
*Purpose: To primarily quantify the costs of LDKT and HD in Nigeria from a ‘payer’s perspective’ and secondarily inform future cost-effectiveness studies to guide health…