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American Transplant Congress abstracts

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Articles tagged "Rejection"

  • 2022 American Transplant Congress

    Is a Single Dose of Steroids in Adult Living Donor Liver Transplant Safe? – A Cohort Analysis

    M. Nunez, C. Praglin, A. M. Torres, E. Agudelo, H. Braun, C. Huang, S. Syed, J. Roberts, G. Roll

    University of California San Francisco, San Francisco, CA

    *Purpose: Steroids increase morbidity, and steroid avoidance (SA) has been studied in deceased donor liver transplant but, little is known about SA in living donor…
  • 2022 American Transplant Congress

    Antibody-Mediated Kidney Allograft Rejection (ABMR) Monitoring and Intervention Based on ABMR Subtypes – A Step Towards Precision Diagnosis and Management

    A. Rizvi1, S. Hussain2, M. Kueht3, J. Fair3, A. Gamilla-Crudo4, M. Mujtaba4

    1Internal Medicine, Nephrology, University of Texas Medical Branch, Galveston, TX, 2University of Texas Medical Branch, Houston, TX, 3Surgery, University of Texas Medical Branch, Galveston, TX, 4University of Texas Medical Branch, Galveston, TX

    *Purpose: The monitoring of kidney allograft for early detection of antibody mediated rejection (ABMR) and subsequent intervention using traditional clinical parameters has been insufficient due…
  • 2022 American Transplant Congress

    Co-stimulation Patways Pd-1 (the Programmed Death 1) And Icos (the Inducible T Cell Co-stimulator) In Peripheral Mononuclear Cells Mesured By Flow Cytometry As A Possible Tool In The Follow-up And Diagnosis Of Kidney Transplant Rejection.

    M. A. Carmona-Escamilla

    Posgrado de Ciencias médicas, Universidad Nacional Autonoma de México, CDMX, Mexico

    *Purpose: Currently, the follow-up of KT in the clinic remains the creatinine levels, this is a highly specific, however, without sensitivity to determine diagnosis of…
  • 2022 American Transplant Congress

    Correlation of Non-HLA Antibodies and Biopsy-Proven Antibody-Mediated Rejection

    N. Patel, M. Kittleson, J. Patel, T. Singer-Englar, S. Kim, D. Chang, E. Kransdorf, D. Megna, J. A. Kobashigawa

    Cedars-Sinai Smidt Heart Institute, Los Angeles, CA

    *Purpose: Non-HLA antibodies are seen in heart transplantation (HTx), but the clinical significance has not been established. In many cases, non-HLA antibodies are drawn, but…
  • 2022 American Transplant Congress

    Chronic Active Antibody Mediated Rejection: 3 Month Response Rates to Treatment and Predictors of Graft Survival

    F. Aziz, M. Jorgenson, S. Parajuli, N. Garg, V. Manchala, E. Yousif, D. Mandelbrot, L. Hidalgo, M. Mohamed, W. Zhong, A. Djamali

    University of Wisconsin, Madison, WI

    *Purpose: There is limited information on effectiveness of treatment and predictors of graft survival following chronic active antibody mediated rejection (cABMR) in kidney transplant recipients…
  • 2022 American Transplant Congress

    Nonadherence Post-Kidney Transplant is Associated with Increased Immune Activation Detected by Peripheral Blood Gene Expression Assay

    M. S. Naseer, H. Shokouh-Amiri, T. Creamer, R. McMillan, S. Tandukar, D. Aultman, G. B. Zibari, N. Singh

    Transplant, John C. McDonald Regional Transplant Center - Willis Knighton Health System, Shreveport, LA

    *Purpose: Nonadherence to immunosuppressive medications is common post-transplantation. We hypothesized that nonadherence results in a heightened alloimmune response in kidney transplant recipients (KTRs), which may…
  • 2022 American Transplant Congress

    Local Intragraft Humoral Immune Response in Chronic Lung Allograft Dysfunction

    E. Miyamoto1, S. C. Juvet2, D. Vosoughi2, J. Wang2, J. Al-Refaee2, T. Daigneault2, A. Duong2, S. Moshkelgosha2, S. Keshavjee2, K. Tinckam2, A. Chruscinski3, D. Hwang4, T. Martinu2

    1Tenri Hospital Japan, University Health Network Canada, Nara, Japan, 2University Health Network, Toronto, ON, Canada, 3Multi-Organ Transplantation, University Health Network, Toronto, ON, Canada, 4Sunnybrook Health Science Centre, Toronto, ON, Canada

    *Purpose: Donor HLA-specific antibody (DSA) and antibody against self-antigens (self-antigen antibody) can cause injury and lead to chronic lung allograft dysfunction (CLAD) after lung transplantation…
  • 2022 American Transplant Congress

    Utility of a Holistic Molecular Paradigm for Kidney Biopsy in the Clinic

    S. Anand1, J. Sanchez-Garcia1, K. Qui2, K. Pinney2, A. Raza1, T. Srinivas2, D. Morris1

    1Intermountain Medical Center, Murray, UT, 2CareDX, South San Francisco, CA

    *Purpose: We report on the clinical utility of a serial dd-cfDNA (donor derived cell free DNA) monitoring coupled with Tissue Transcriptomics (Tr) and Histology (Hx)…
  • 2022 American Transplant Congress

    A Novel Approach to Non-Invasive Multimodality Testing with Allosure and Allomap Predicts Microvascular Inflammation with High Accuracy in Kidney Transplant Recipients

    S. Parajuli, F. Aziz, N. Garg, S. E. Panzer, K. Van Hyfte, K. Degner, S. Reese, L. Ptak, N. Wilson, A. Djamali

    University of Wisconsin, Madison, WI

    *Purpose: The most prominent histologic lesion in antibody-mediated rejection (ABMR) is microvascular inflammation (MVI); however, its recognition and scoring can be challenging and poorly reproducible…
  • 2022 American Transplant Congress

    Outcomes in Renal Transplant Recipients Receiving Pre-Transplant Financial Assistance Through the American Kidney Fund

    H. Roppo1, P. Klem1, B. Crowther1, E. Sartain1, K. Schoeppler1, P. T. Kennealey2, B. Kaplan3

    1Department of Pharmacy, University of Colorado Hospital, Aurora, CO, 2Department of Surgery, University of Colorado Hospital, Aurora, CO, 3Department of Renal Med Diseases/Hypertension, University of Colorado Hospital, Aurora, CO

    *Purpose: Pre-transplant financial assistance for insurance premiums is available for eligible patients through the American Kidney Fund (AKF), but this funding ends within the first…
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