2020 American Transplant Congress
Influence of the Gut Microbiota on Acute Rejection of Vascular Allografts
Molecular Biology and Biochemistry, Simon Fraser University, Burnaby, BC, Canada
*Purpose: The gut microbiota influences immune responses in many ways but its involvement in transplant rejection is poorly understood. We have examined how changes in…2020 American Transplant Congress
Differences in Alemtuzumab Dosing Does Not Affect Early Kidney Transplant Outcomes
Wake Forest Baptist Health, Winston-Salem, NC
*Purpose: Alemtuzumab (Alem) is a widely used medication for induction therapy in kidney transplantation. However, there is limited evidence comparing outcomes with low versus high…2020 American Transplant Congress
Efficacy & Safety of Once Daily Tacrolimus Compared to Twice Daily Tacrolimus after Liver Transplantation
*Purpose: To compare the efficacy and safety of once daily prolonged release tacrolimus compared to twice daily tacrolimus in liver transplantation patients*Methods: Medline, EMBASE, CENTRAL…2020 American Transplant Congress
The Art Rather Than the Science of Non-HLA Antibody Mediated Rejection in Heart Transplantation: A Single Center Experience
Cardiology, Baylor University Medical Center, Dallas, TX
*Purpose: The role of non-HLA antibodies (Ab) in HLA-DSA negative antibody mediated rejection (AMR) following heart transplant (HTx) remains largely unknown.*Methods: Retrospective analysis of all…2020 American Transplant Congress
The 1st Year Posttransplant Course Reliably Predicts Kidney Graft Survival up to 15 Years Using a Machine Learning-Based Modeling Approach
Hannover Medical School, Hannover, Germany
*Purpose: Identification of patients at risk for graft failure can improve individual surveillance and early therapeutic interventions. We used a well-documented patient cohort to establish…2020 American Transplant Congress
The Role of Th17 Polarized T Regulatory Cells in Intestinal Transplant Rejection
*Purpose: Despite profound advances in immunosuppression, intestinal transplantation (ITx) is plagued by frequent cellular rejection. T regulatory cells (Tregs) are key in mitigating immune cell…2020 American Transplant Congress
De Novo DSA in the Setting of Stable Renal Allograft Function Does Not Impair Long-Term Graft Survival
*Purpose: To determine the long-term outcome of renal allograft recipients with de novo DSA (dnDSA) in the setting of stable allograft function.*Methods: A single-center review…2020 American Transplant Congress
The Histological Picture of Indication Biopsies in the First Days after Renal Transplantation
Microbiology, Immunology and Transplantation, KU Leuven, Leuven, Belgium
*Purpose: In preclinical studies, ischemia reperfusion injury and older donor age are associated with renal inflammation in the early phase after transplantation. In human kidney…2020 American Transplant Congress
Factors Influencing Background Cell-Free DNA Levels: Implications for Donor-Derived Cell-Free DNA Assessment in Transplant Patients
*Purpose: Detecting elevated levels of donor-derived cell-free DNA (dd-cfDNA) in the plasma of transplant recipients has been used as a metric to determine graft injury…2020 American Transplant Congress
The Impact of Thy1 Expression of Fibroblast for Chronic Lung Allograft Dysfunction
*Purpose: Chronic lung allograft dysfunction (CLAD) result from excessive immune activation and excessive collagen deposition by fibroblasts within the lung parenchyma or airway.Bronchiolitis obliterans (OB)…
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