2016 American Transplant Congress
The Impact of Ritonavir-Boosted Protease Inhibitors and Non-Depleting Antibody Induction on Outcomes in HIV-Infected Kidney Transplant Recipients.
Mount Sinai Hospital, New York.
Background: One-year rejection rates in HIV-infected kidney transplant recipients range from 15-40%, compared to overall rejection rates of 10% in HIV-negative patients. Protocols for immunosuppression…2016 American Transplant Congress
Mapping Heterogeneity in Antibody-Mediated Rejection Using Molecular Phenotypes and Archetype Analysis.
Archetype analysis is a method for identifying new relationships among samples without subdividing them into classes, finding a limited number of archetypical cases and calculating…2016 American Transplant Congress
Randomized Controlled Study Evaluating Adherence Monitoring with Electronic Feedback on Reducing Renal Allograft Rejection.
Transplant Center, University of Chicago, Chicago, IL.
Purpose: The negative impact of non-adherence to the immunosuppressant medication (IM) regimen on transplant outcomes is well recognized. In an attempt to improve outcomes, the…2016 American Transplant Congress
Implications of Subclinical Borderline Acute Cellular Rejection Detected in Protocol Biopsies on Graft Outcomes.
Background: The effects of subclinical borderline acute cellular rejection (BACR-defined as I1T1 per Banff criteria) detected in protocol biopsies (Bx) on subsequent graft function and…2016 American Transplant Congress
Absence of Acute Allograft Rejection in the Early Post Operative Period in a Full Face VCA Recipient with a Positive B-Cell Flow Cytometric Crossmatch Utilizing an Induction Immunosuppression Regimen Including Anti-thymocyte and Anti-CD20 Agents.
Background: The presence of donor-specific antibodies (DSA) to human leukocyte antigen (HLA) convey increased risk of allograft rejection. Patients suffering full-thickness burns to the face…2016 American Transplant Congress
Clinical Outcome in Pure T-Cell Mediated Acute Rejection of the Kidney with No Donor Specific Antibody or C4d Staining.
Background: T-cell mediated rejection (TCMR) is now considered to have little impact on renal graft function. This study re-evaluated the histologic phenotypes and clinical significance…2016 American Transplant Congress
Influence of Inclusion of the Liver on the Outcome After Intestinal Transplantation.
1Abdominal Transplantation, UZ Leuven, Leuven, Belgium; 2Pathology, UZ Leuven, Leuven, Belgium.
Introduction: Intestinal transplantation (ITx) is indicated when life-threatening complications occur following chronic total parenteral nutrition in intestinal failure patients. Several complications (TPN related irreversible liver…2016 American Transplant Congress
Acute Rejections and Incidence of De Novo DSA Depend on Donor Factors and Deceased Donor Kidney Associated Risk Assessed by the Kidney Donor Profile Index (KDPI).
Nephrology, Charite, Berlin, Germany.
Introduction: Little data exist analyzing the influence of donor kidney quality on the immunologic outcome and applying the KDPI in a European cohort.Methods: This retrospective…2016 American Transplant Congress
Antibody Titers as Predictors of Kidney Graft Outcomes.
PURPOSE: Development of de novo donor specific antibody (dnDSA) following kidney transplantation is not uncommon. As laboratory techniques advance, rates of dnDSA have increased. However,…2016 American Transplant Congress
Assessment of mRNA Gene Profiles in Plasma Exosome to Predict Risk for Antibody-Mediated Rejection (ABMR) of Renal Allografts.
Background: ABMR is a major obstacle for successful transplant in HLA-sensitized (HS) patients. Complement-mediated and antibody-dependent cellular cytotoxicity (ADCC) are primarily mechanisms for ABMR. Previously…
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