2016 American Transplant Congress
Composite Score to Define the Risk of Allograft Loss After Standard-of-Care Treatment of Antibody-Mediated Rejection in Kidney Transplantation.
The development of a reliable surrogate endpoint for allograft survival after AMR treatment is a current unmet need in clinical transplantation (FDA AMR Workshop). We…2016 American Transplant Congress
mRNA Expression of BAFF and APRIL Receptors Increases in Acute Rejection in Kidney Transplant Recipients.
Introduction:BAFF and APRIL are known survival and growth of B- cells.BAFF and APRIL share two receptors i-TACI and ii- BCMA. Additionally, BAFF has strong affinity…2016 American Transplant Congress
Early De Novo DSA with T Cell Mediated Rejection (TCMR) Is Associated with Allograft Dysfunction with Chronic Injury.
De novo anti-donor HLA specific antibody (DSA) detected post-renal transplantation is associated with adverse outcomes. However, the relationship between early de novo DSA and subsequent…2016 American Transplant Congress
Acute Rejection Profoundly Impacts Graft Survival in Young but Not in Old Kidney Transplant Recipients.
Background: The proportion of marginal grafts and elderly recipients awaiting kidney transplantation is ever increasing. The correlation of age with DGF and acute rejection determines…2016 American Transplant Congress
Delayed Graft Function Is an Independent Risk Factor for Renal Allograft Rejection.
Background: Numerous risk factors for delayed graft function (DGF) after kidney transplantation (KTx) have been identified. However the effect of DGF as an independent risk…2016 American Transplant Congress
Relationship Between Changes in Brain Natriuretic Peptide Levels and Cardiac Allograft Rejection Early After Heart Transplantation.
1University of Colorado, Aurora, CO; 2Vanderbilt University, Nashville, TN.
Endomyocardial biopsies (EMBs) are routinely used to detect cardiac allograft rejection after heart transplantation (HTx), but they are invasive and costly. Serial changes in brain…2016 American Transplant Congress
Tacrolimus as a Tool for Intracellular Assessment of von Willebrand Factor Production by Activated Human Glomerular Endothelial Cells.
Renal Division, University Health Center (CHU) of Quebec, Laval University, Quebec, QC, Canada.
Background: Von Willebrand factor (vWF) is a prothrombotic mediator stored in intracytoplasmic granules within endothelial cells and is released by endothelial exocytosis, leading to microangiopathic…2016 American Transplant Congress
Allograft TLR4 Receptor Signaling Induces Specific Early Inflammatory Events in Promotes Allografts Subjected to Prolonged Cold Ischemic Storage.
Dept. Immunology and Glickman Urological Institute, Cleveland Clinic, Cleveland, OH.
Engagement of Toll-like receptors (TLR) by endogenous danger-associated molecular pattern ligands contributes to the intensity of tissue inflammation, including the inflammation generated during ischemia-reperfusion injury…2016 American Transplant Congress
The Impact of Microvascular Inflammation (MVI) in Kidney Transplant Biopsies (KTxBx) Is Independent of Time Post-Transplant.
Detection of MVI in a KTxBx, often associated with antibody mediated rejection, is associated with a poor prognosis for kidney graft survival. However most information…2016 American Transplant Congress
Acute Rejection, New-Onset Diabetes After Transplant and Transplant Outcomes in Pediatric Kidney Recipients: Analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing (OPTN/UNOS) Database.
Nephrology, UCLA, Los Angeles, CA.
Introduction Our objective was to identify the associations of new-onset diabetes after transplant (NODAT) and acute rejection (AR) in predicting patient mortality and transplant failure…
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