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Articles tagged "Recurrence"

  • 2022 American Transplant Congress

    Possible Recurrence Must Not Limit Kidney Transplantations for Patients with Focal Segmental Glomerulosclerosis

    A. Angeletti, M. Gentile, G. Ghiggeri, M. Bruschi, F. Lugani, G. Caridi

    Istituto Giannina Gaslini, Genova, Italy

    *Purpose: Non-genetic forms of Focal Segmental Glomerulosclerosis (FSGS) are at high risk of recurrence after kidney transplant (KT) (55%), when compared to inherited forms (0-4%)…
  • 2022 American Transplant Congress

    A Pathway for Establishing Etiology of Kidney Failure: An Academic Transplant Center’s Experience with a Broad Kidney Gene Panel

    R. Sodhi1, K. Brossart2, A. Desai1, D. J. Arwindekar1, H. Tabriziani2, S. Akkina1

    1Loyola University Medical Center, Maywood, IL, 2Natera, Inc., Austin, TX

    *Purpose: Assessing genetic causes of kidney failure can inform pre-transplant decision making and may improve post-transplant outcomes. Here we describe an academic transplant center’s experience…
  • 2021 American Transplant Congress

    Integrative Analyses of Circulating Small Rnas and Paired Kidney Graft Transcriptome in Transplant Glomerulopathy

    C. Kuscu1, K. Manjari2, M. Akram3, C. Kuscu4, A. Wolen,4, A. Bajwa4, J. Eason4, D. G. Maluf5, V. Mas6, E. Akalin7

    1Surgery, James D Eason Transplant Institute, UTHSC, Memphis, TN, 2Department of Systems and Computational Biology, School of Life Sciences, University of Hyderabad,, Hyderabad,, India, 3Center for Biomedical Informatics, University of Tennessee Health Science Center, Memphis, TN, 4Surgery, James D Eason Transplant Institute, Memphis, TN, 5Surgery, Program in Transplantation, University of Maryland, Baltimore, MD, 6Surgery, Division Surgical Science, University of Maryland, Baltimore, MD, 7Medicine, Montefiore Medical Center, Abdominal Transplant Program, Albert Einstein College of Medicine,, NYC, NY

    *Purpose: Transplant glomerulopathy (TG) develops through multiple mechanisms including donor-specific antibodies, T cells and innate immunity. We investigate the role of circulating small RNAs (sRNAs)…
  • 2021 American Transplant Congress

    HLA Allele Association with Recurrent Iga Nephropathy After Kidney Transplantation

    O. Alzahabi, M. Merzkani, H. Murad, A. Java, R. Delos Santos, T. Alhamad, A. Malone

    Transplant, Washington University, Saint Louis, MO

    *Purpose: IgA nephropathy is one of the most common glomerulonephritis after kidney transplantation. The association of IgA nephropathy recurrence with recipient HLA typing is not…
  • 2020 American Transplant Congress

    Beyond Milan- Not Paying the Price

    A. Mathur, C. Brennan, D. Tsapepas, M. Najjar, O. Perez, A. Griesemer, T. Kato, J. Emond

    Columbia University, New york, NY

    *Purpose: Early stage hepatocellular carcinoma (HCC) patients meeting the Milan Criteria have access to Orthotopic Liver Transplantation (OLT) as a curative treatment. However, a substantial…
  • 2020 American Transplant Congress

    Imaging Features and Diagnostic Accuracy of MRI in Combined Hepatocholangiocarcinoma

    M. Najjar1, J. Makkar1, S. Sun1, J. Zou1, O. Perez1, P. Jiang1, Y. Saenger1, E. Zheng1, E. Verna1, A. Mathur1, A. Griesemer1, K. Halazun2, B. Samstein2, T. Kato1, J. Emond1

    1Columbia University Medical Center/New-York Presbyterian, New York, NY, 2Weill Cornell Medicine, New York, NY

    *Purpose: Combined hepatocholangiocarcinomas (HCC-CCA) are rare tumors with both hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) differentiations. They are usually associated with a worse prognosis after…
  • 2020 American Transplant Congress

    Methenamine for Prevention of Recurrent Urinary Tract Infections in Adult Solid Organ Transplant Recipients

    H. Sweiss1, S. Bhayana2, R. Hall1, J. Nelson1, E. Kincaide1

    1University Health System, The University of Texas at Austin, College of Pharmacy, Pharmacotherapy Division, Austin, TX, The University of Texas Health Science Center at San Antonio, San Antonio, TX, 2University Health System, The University of Texas Health Science Center at San Antonio, San Antonio, TX

    *Purpose: Evaluate efficacy of methenamine for prevention of recurrent urinary tract infections (rUTI) in transplant recipients.*Methods: This retrospective review included patients greater than or equal…
  • 2020 American Transplant Congress

    Prognostic Impact of Peritumoral Neutrophil Infiltration on Hepatocellular Carcinoma Recurrence Following Liver Transplantation

    M. Najjar1, K. Halazun2, M. Mondal1, A. Srivastava1, M. Moore1, E. Rizk1, R. Gartrell1, H. Remotti1, L. Fazlollahi1, E. Verna1, A. Griesemer1, A. Mathur1, B. Samstein2, J. Emond1, Y. Saenger1

    1Columbia University Irving Medical Center, New York, NY, 2Weill Cornell Medicine, New York, NY

    *Purpose: Peritumoral neutrophil (PMN) infiltration has been associated with poor clinical outcomes in various tumors; however, its role in hepatocellular carcinoma (HCC) remains understudied. Moreover,…
  • 2020 American Transplant Congress

    Recurrent Focal Segmental Glomerulosclerosis and the Possibility of Re-Transplantation

    E. L. Wood1, J. Burrows1, E. Lum, MD2, J. Veale, MD1

    1Urology, UCLA, Los Angeles, CA, 2Nephrology, UCLA, Los Angeles, CA

    *Purpose: Up to 30% of patients with focal segmental glomerulosclerosis (FSGS) experience recurrent disease after renal transplant, with high rates of progression to allograft failure…
  • 2020 American Transplant Congress

    Factors Associated with Hepatocellular Carcinoma Understaging for Liver Transplantation, and Variation in Understaging by Transplant Center

    N. Mahmud1, M. Hoteit1, D. Goldberg2

    1Hospital of the University of Pennsylvania, Philadelphia, PA, 2University of Miami, Miami, FL

    *Purpose: Hepatocellular carcinoma (HCC) may be cured by liver transplantation (LT) in selected patients, though recurrence rates remain high. Patients who are reported as within…
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