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Articles tagged "Protocol biopsy"

  • 2019 American Transplant Congress

    Mesangiopathic Glomerulonephritis in Kidney Transplants

    G. Towns, G. Agarwal, S. Ong, R. Mundra, C. Kew

    UAB, Birmingham, AL

    *Purpose: Describe higher than anticipated prevalence of Mesangiopathic Glomerulonephritis on surveillance biopsies.*Methods: Review of all surveillance biopsies from September 2014 through September 2018 for presence…
  • 2019 American Transplant Congress

    When to Hold: Apixaban in Renal Transplant Recipients

    V. H. Do1, D. Haakinson2, K. D. Belfield1

    1Yale New Haven Hospital, New Haven, CT, 2Yale School of Medicine, New Haven, CT

    *Purpose: Renal transplant recipients (RTRs) may develop deep venous thrombosis (DVT), pulmonary embolism (PE), or atrial fibrillation requiring treatment with oral anticoagulation. There is limited…
  • 2019 American Transplant Congress

    Impact of Six-Month Surveillance Biopsies and Monitoring on 2-Year Outcomes in Pediatric Renal Transplant Recipients

    J. Lyons1, D. Ranch2, R. Hall1, P. Maxwell1, K. Hitchman2, B. Crowther1

    1University Health System, The University of Texas at Austin, College of Pharmacy, Pharmacotherapy Division, Austin, TX, The University of Texas Health Science Center at San Antonio, San Antonio, TX, 2University Health System, The University of Texas Health Science Center at San Antonio, San Antonio, TX

    *Purpose: Evaluate the utility of surveillance biopsies on post-transplant outcomes.*Methods: A retrospective single center chart review of pediatric renal transplant recipients from 01/2011-10/2015 was conducted.…
  • 2019 American Transplant Congress

    Effect of Race and Antibody-Mediated Injury on Outcomes after Early Subclinical Inflammation

    E. P. Kasik, M. E. Seifert, M. Bernard, G. Agarwal, H. Fatima, R. Gaston, B. Julian, C. Kew, V. Kumar, S. Mehta, S. Ong, F. Rosenblum, G. Towns, R. B. Mannon

    University of Alabama, Birmingham, AL

    *Purpose: The impact of subclinical inflammation (SCI) on transplant outcomes has been variable, based on previous studies in homogeneous cohorts with relatively low immunologic risk.…
  • 2018 American Transplant Congress

    Determining the Utility of Protocol Biopsies in Kidney Transplant Recipients

    J. Patel,1 K. Heshmati,2 A. Rogers,1 R. Wali,2 J. Jonsson,2 C. Liu,2 E. Emery,2 D. Collins,2 S. Karzai,2 J. Piper.2

    1Virginia Commonwealth University, Falls Church; 2Inova Fairfax Hospital, Falls Church.

    Protocol biopsies may allow for early detection and treatment of kidney transplant rejection or other correctable pathology, leading to improved graft survival. Unfortunately, biopsies may…
  • 2018 American Transplant Congress

    IgA Recurrence in a Single Center with a Protocol Biopsy Program

    M. Merzkani, N. Lepori, M. El Ters, F. Cosio, H. Amer.

    Mayo Clinic, Rochester, MN.

    The objective of this study was to determine the rate of recurrence of IgA nephropathy in our program aided by protocol biopsies and protocol driven…
  • 2018 American Transplant Congress

    A Substantial Fraction of Surveillance Transplant Biopsies Have Clinically Actionable Findings

    A. Shammout,1 A. Naik,2 M. Samaniego,2 E. Farkash.1

    1Pathology, Michigan Medicine, Ann Arbor; 2Nephrology, Michigan Medicine, Ann Arbor.

    Background: Surveillance biopsies in renal transplant recipients may detect subclinical disease that affects graft longevity. At our transplant center, most patients with stable allograft function…
  • 2018 American Transplant Congress

    Protocol Biopsies after Paediatric Kidney Transplantation: A Single Centres' 17 Year Experience

    T. Alsulaimi,1 M. Aloufi,2 S. Grisaru,1 S. Samuel,1 L. Hamiwka.1

    1Paediatric Nephrology, University of Calgary, Calgary, AB, Canada; 2Pediatric Nephrology, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.

    PURPOSE: Standard laboratory measures are not sensitive indicators of kidney dysfunction following transplantation and may be less reliable in paediatric recipients. Early graft surveillance may…
  • 2018 American Transplant Congress

    Sub-Clinical Acute Rejection (subAR) Detected by Both Surveillance Biopsy (SBx) and a Peripheral Blood Molecular Biomarker Correlates with De Novo Donor Specific Antibody (dnDSA) Following Kidney Transplant (KT)

    R. Heilman,1 J. Friedewald,2 K. Kurian,5 T. Whisemant,5 E. Poggio,3 C. Marsh,5 P. Baliga,7 N. Bridges,4 J. Odim,4 M. Brown,4 D. Ikle,3 B. Armstrong,3 L. Zhao,2 D. Salomon,5 M. Abecassis.2

    1Mayo Clinic, Phoenix; 2Northwestern University, Chicago; 3Rho Federal Systems, Chapel Hill; 4National Institute of Allergy and Infectious Disease, Bethesda; 5Scripps Health, La Jolla; 6Cleveland Clinic, Cleveland; 7Medical University of South Carolina, Charleston.

    AIMWe investigated the correlation between subAR diagnosed by SBx or by a newly-defined biomarker, and the development of dnDSA.METHODS307 KT patients enrolled into a multi-center…
  • 2018 American Transplant Congress

    Impact of Direct Antiviral Therapy for Hepatitis C on Acute Rejection and DSA Formation in Kidney Transplant Recipients

    Z. Zaky, S. Armanyous, L. Herlitz, E. Poggio, J. Augustine.

    Cleveland Clinic, Cleveland, OH.

    Background: Hepatitis C virus infection (HCV) has historically portended a poor outcome after kidney transplantation. With recent advent of direct antiviral agents (DAA), there has…
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