2019 American Transplant Congress
Effect of Race and Antibody-Mediated Injury on Outcomes after Early Subclinical Inflammation
University of Alabama, Birmingham, AL
*Purpose: The impact of subclinical inflammation (SCI) on transplant outcomes has been variable, based on previous studies in homogeneous cohorts with relatively low immunologic risk.…2019 American Transplant Congress
Recurrent Diabetic Nephropathy Despite Intensive Glycemic Control: An Observational Cohort Study
*Purpose: After kidney transplantation, recurrence of diabetic nephropathy has been reported. The presentation and kinetics of recurrent diabetic nephropathy and its risk factors remain however…2019 American Transplant Congress
Humoral Immune Responses to Kidney Associated Non-HLA Antigens is Not Associated with Progression to Chronic Immune Injury in Kidney Transplant Recipients
1Mayo Clinic, Phoenix, AZ, 2St. Joseph’s Hospital, Phoenix, AZ
*Purpose: Development of donor specific anti-HLA (DSA) although is a known risk factor for Chronic immune injury (CII), it is undetectable in many patients with…2019 American Transplant Congress
IL-6R Blockade with Tocilizumab Increases Tregs and Decreases Early Graft Inflammation in Kidney Transplant Recipients: Results of a Randomized Controlled Trial
*Purpose: IL-6, a proinflammatory cytokine and key regulator of Treg/Th17 balance, is strongly associated with renal graft rejection. We hypothesized that IL-6 blockade with tocilizumab…2018 American Transplant Congress
IgA Recurrence in a Single Center with a Protocol Biopsy Program
The objective of this study was to determine the rate of recurrence of IgA nephropathy in our program aided by protocol biopsies and protocol driven…2018 American Transplant Congress
A Substantial Fraction of Surveillance Transplant Biopsies Have Clinically Actionable Findings
1Pathology, Michigan Medicine, Ann Arbor; 2Nephrology, Michigan Medicine, Ann Arbor.
Background: Surveillance biopsies in renal transplant recipients may detect subclinical disease that affects graft longevity. At our transplant center, most patients with stable allograft function…2018 American Transplant Congress
Protocol Biopsies after Paediatric Kidney Transplantation: A Single Centres' 17 Year Experience
PURPOSE: Standard laboratory measures are not sensitive indicators of kidney dysfunction following transplantation and may be less reliable in paediatric recipients. Early graft surveillance may…2018 American Transplant Congress
Sub-Clinical Acute Rejection (subAR) Detected by Both Surveillance Biopsy (SBx) and a Peripheral Blood Molecular Biomarker Correlates with De Novo Donor Specific Antibody (dnDSA) Following Kidney Transplant (KT)
AIMWe investigated the correlation between subAR diagnosed by SBx or by a newly-defined biomarker, and the development of dnDSA.METHODS307 KT patients enrolled into a multi-center…2018 American Transplant Congress
Impact of Direct Antiviral Therapy for Hepatitis C on Acute Rejection and DSA Formation in Kidney Transplant Recipients
Cleveland Clinic, Cleveland, OH.
Background: Hepatitis C virus infection (HCV) has historically portended a poor outcome after kidney transplantation. With recent advent of direct antiviral agents (DAA), there has…2018 American Transplant Congress
Subclinical Borderline Rejection: More Than Meets the Eye?
UAB School of Medicine, Birmingham.
Purpose: Surveillance biopsies can detect subclinical T cell mediated rejection (SC-TCMR) or subclinical borderline rejection (SC-B-TCMR) in patients with normal/stable creatinine, but the impact on…
American Transplant Congress abstracts