ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Preservation"

  • 2018 American Transplant Congress

    The Superiority of Plasma Enriched Perfusate for Assessment of Donor Kidneys in an Ex-Vivo Normothermic Perfusion (EVNP) Setting

    J. Palma, I. Palma, Y. Smolin, A. Perry, J. Sageshima, R. Perez.

    Surgery, Transplant Division, UC Davis Health System, Sacramento, CA.

    EVNP has been used to assess and repair marginal organs prior to transplantation but the optimal perfusate composition is unknown. We hypothesize that EVNP with…
  • 2018 American Transplant Congress

    The Role of Ex Vivo Normothermic Preservation in Minimizing Postreperfusion Syndrome in Liver Transplantation

    A. Hassan, J. Cywinski, Q. Liu, D. Pezzati, D. Yang, L. Liu, G. Iuppa, K. Hashimoto, F. Aucejo, M. Fujiki, B. Eghtesad, S. Irefin, J. Fung, K. Abu-Elmagd, C. Miller, C. Quintini.

    Transplant Surgery, Cleveland Clinic, Cleveland.

    Background:Graft reperfusion holds a major challenge during liver transplantation. NMP may improve post-reperfusion hemodynamics, reduce vasopressor and blood product transfusion.Methods:15 patients with liver transplantation after…
  • 2018 American Transplant Congress

    Ex-Situ Normothermic Human Upper Extremity Perfusion: Preliminary Report

    V. Fahradyan, E. Dalla Pozza, M. Madajka, K. Cho, N. Dawlagala, E. Duraes, H. Shah, S. Al-deen Said, C. Ordenana, F. Papay, A. Rampazzo, B. Bassiri Gharb.

    Plastic Surgery, Cleveland Clinic, Cleveland, OH.

    Purpose: Ischemia time remains a significant limiting factor for successful extremity replantation and transplantation. Normothermic ex-situ perfusion is a novel method of a limb preservation…
  • 2018 American Transplant Congress

    Evaluation of a Marine OXYgen Carrier (Hemo2Life®) for Organ Preservation: First Use in Kidney Transplantation in Humans

    Y. Le Meur,1 E. Morellon,2 M. Essig,3 A. Thierry,4 M. Buchler,5 S. Drouin,6 C. Deruelle,1 L. Badet,2 F. Pesteil,3 P-.O. Delpech,4 J-.M. Boutin,5 B. Barrou.6

    1Transplantation, University Hospital, Brest, France; 2Hopital Edouard Herriot, Lyon, France; 3University Hospital, Limoges, France; 4University Hospital, Poitiers, France; 5University Hospital, Tours, France; 6La Pitié Salpetrière, Paris, France.

    Preventing ischemia/reperfusion injuries (IRIs) is a major issue in organ transplantation. At present, grafts are preserved at 4[deg]C in preservation solution in order to reduce…
  • 2018 American Transplant Congress

    A Cost Analysis on Normothermic Machine Perfusion at a Single Center

    D. Pezzati, Q. Liu, H. Hassan, G. Iuppa, L. Hernandez, G. D'Amico, T. Diago Uso, B. Heghtsad, C. Miller, C. Quintini.

    General Surgery, Cleveland Clinic, Cleveland, OH.

    INTRODUCTION: Normothermic machine perfusion (NMP) for liver transplantation is a novel and promising technique.One of the concerns related to its usage is the high cost.The…
  • 2018 American Transplant Congress

    Hypothermic Oxygenated Machine Perfusion in Liver and Kidney Transplantation of Extended Criteria Donors: A Phase-1 of Clinical Trial

    M. Ravaioli,1 V. De Pace,1 M. Cescon,1 M. Del Gaudio,1 V. R. Bertuzzo,1 A. Siniscalchi,1 A. D'Errico,2 G. Comai,2 G. La Manna,2 A. D. Pinna.1

    1General Surgery and Transplantation, University of Bologna Sant'Orsola - Malpighi Hospital, Bologna, Emilia Romagna, Italy; 2Experimental Diagnostic and Specialty Medicine, University of Bologna Sant'Orsola- Malpighi Hospital, Bologna, Emilia Romagna, Italy.

    In the field of liver (LT) and kidney transplantation (KT), extended criteria donors (ECD) offer an additional organ source that is more vulnerable for early…
  • 2018 American Transplant Congress

    One-Pump versus Two-Pump Normothermic Ex Vivo Perfusion Machines in Discarded Human Livers

    A. Hassan, Q. Liu, D. Pezzati, A. Nassar, B. Soliman, M. Blum, P. Grady, G. Iuppa, T. Uso, J. Fung, K. Abu-Elmagd, C. Quintini.

    Transplant Surgery, Cleveland Clinic, Cleveland.

    Introduction:Physiologic flows and pressures need to be provided by the ex vivo liver perfusion device. We hypothesized that the 1-pump designed machines would provide the…
  • 2018 American Transplant Congress

    Resuscitation and Viability Testing of Initially Declined Livers Using Sequential Hypo- and Normothermic Machine Perfusion with an Acellular Fluid

    Y. de Vries,1,2 A. Matton,1,2 S. Karangwa,1,2 M. Nijsten,3 R. de Kleine,2 A. van den Berg,4 V. de Meijer,2 P. Meyer,5 M. de Boer,2 R. Porte.2

    1Surgical Research Laboratory, University of Groningen, University Medical Center Groningen, Groningen, Netherlands; 2Section of HPB Surgery and Liver Transplantation, University Medical Center Groningen, Groningen, Netherlands; 3Department of Critical Care, University Medical Center Groningen, Groningen, Netherlands; 4Department of Gastroenterology and Hepatology, University Medical Center Groningen, Groningen, Netherlands; 5Department of Anesthesiology, University Medical Center Groningen, Groningen, Netherlands.

    While end-ischemic dual hypothermic oxygenated machine perfusion (DHOPE) resuscitates mitochondria and reduces ischemia-reperfusion injury, normothermic machine perfusion (NMP) allows for ex-situ functional testing of donor…
  • 2018 American Transplant Congress

    Ischemia-Free Liver Transplantation for Fatty Liver Grafts in Human

    W. Ju, S. Huang, Z. Guo, G. Chen, X. He.

    Organ Transplant Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

    BACKGROUND&AIMS: Fatty liver diseases have led to a continuous increase of available donor livers containing fat. Fatty liver grafts were identified as an independent risk…
  • 2018 American Transplant Congress

    Unraveling the Neuroimmunological Pathways Surrounding Brain Death: Systematic Study of Clinically Relevant Serum Biomarker Changes during Donor Management from Admission to Procurement

    K. Bera, M. LoFaro, H. Huang, S. Maslau, R. Ploeg.

    Nuffield Department of Surgical Sciences, University of Oxford, Oxford, United Kingdom.

    Donation after brain death (BD) remains an important source of transplanted organs worldwide and it has been shown that BD causes a hostile environment with…
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