Articles tagged "Prediction models"

2017 American Transplant Congress
How Much Is a Kidney Worth? Comparing Kidney Transplant Strategies in Liver Transplant Candidates.
X. Cheng,¹ W. Kim,² J. Tan,¹ J. Goldhaber-Fiebert.³
¹Div Nephrology, ; ²Div Gastroenterology & Hepatology, ; ³Ctr Health Policy, Stanford U, Palo Alto
The number of simultaneous liver-kidney (SLK) transplants for renal failure complicating end-stage liver disease (ESLD) is rising. The Organ Procurement and Transplant Network (OPTN) will…
2017 American Transplant Congress
Screening and Referral of High Risk Liver Transplant Recipients to a Transitional Care Coordination (TCC) Program to Reduce Hospital Readmissions.
A. Masoumi,¹ J. Krzyzewski,¹ T. Stern,¹ N. Schluterman,² D. Bruno,² J. Bromberg,² R. Barth,² S. Hanish.²
¹University of Maryland Medical Center, Baltimore, MD; ²University of Maryland School of Medicine, Baltimore, MD
Introduction One-fifth of Medicare patients are readmitted to the hospital. The readmission rate among liver transplant recipients at a large tertiary academic medical center in…
2017 American Transplant Congress
Maximizing the Potential of Treg-Based Therapies for Transplant Rejection via Computational Immune-Modeling: Effect of Dose, Timing, and Distribution.
G. Raimondi,¹ A. Arun,¹ O. Dorabiala,² J. Arciero.³
¹Plastic & Reconstructive Surgery, Johns Hopkins University, Baltimore; ²Mathematics, Pennsylvania State University, Philadelphia; ³Mathematical Sciences, Indiana University-Purdue University Indianapolis, Indianapolis
Purpose. Regulatory T cells (Treg), endogenous regulators of the immune system, have a significant therapeutic potential for prevention of transplant rejection. Experimental evidences however, indicate…
2017 American Transplant Congress
A Markov Model for Transplant & Renal Outcomes After Liver & Simultaneous Liver-Kidney Transplants.
X. Cheng,¹ W. Kim,² J. Tan,¹ J. Goldhaber-Fiebert.³
¹Div Nephrology, Stanford U, Palo Alto; ²Div Gastroenterology & Hepatology, Stanford U, Palo Alto; ³Ctr Health Policy, Stanford U, Palo Alto
The Organ Procurement and Transplant Network (OPTN) will implement a set of clinical criteria for simultaneous liver-kidney (SLK) transplant eligibility. Our aim is to build…
2017 American Transplant Congress
A Multidimensional Prognostic Score and Nomogram to Predict Kidney Transplant Survival: The Integrative Box (iBox) System.
A. Loupy,¹ O. Aubert,¹ B. Orandi,² A. Jackson,² M. Naesens,³ N. Kamar,¹ O. Thaunat,¹ E. Morelon,¹ M. Delahousse,¹ D. Viglietti,¹ D. Glotz,¹ C. Legendre,¹ X. Jouven,¹ R. Montgomery,² M. Stegall,⁴ D. Segev,² C. Lefaucheur.¹
¹Paris Translational Research Center for Organ Transplantation, Paris, France; ²Johns-Hopkins, Baltimore; ³Leuven University, Leuven, Belgium; ⁴Mayo Clinic, Rochester
The transplant field currently lacks of robust risk stratification models leading to major problems for clinical care, clinical trials, and medical progress. The goal of…
2017 American Transplant Congress
Improved Outcome of Kidney Transplants by Donor Recipient Matching Based on Predicted Indirectly Recognizable HLA Epitopes.
O. Staeck,¹ M. Niemann,⁴ F. Halleck,¹ D. Khadzhynov,¹ C. Schönemann,² P. Reinke,¹ E. Spierings,³ K. Budde,¹ N. Lachmann.²
¹Nephrology, Charité Universitaetsmedizin, Berlin, Germany; ²HLA Laboratory, Charité Universitaetsmedizin, Berlin, Germany; ³Laboratory of Translational Immunology, UMC Utrecht, Utrecht, Netherlands; ⁴PIRCHE, Berlin, Germany
Introduction: De novo donor-specific HLA antibodies (dnDSA) are recognized as a risk factor for graft loss. Determinants of DSA specificity are generated via the indirect…
2017 American Transplant Congress
Predicting Recurrence Prior to Transplant: The Response of HCC to Chemoembolization.
T. Sandow,¹ H. Bohorquez,² D. Kirsch,¹ P. Thevenot,³ K. Nunez,³ A. Albar,¹ D. DeVun,¹ J. Gimenez,¹ G. Galliano,⁴ A. Cohen,² G. Loss,² D. Kay,¹ P. Gulotta.¹
¹Radiology, Ochsner Clinic Foundation, New Orleans, LA; ²Transplant Surgery, Ochsner Clinic Foundation, New Orleans, LA; ³Institute of Translational Research, Ochsner Clinic Foundation, New Orleans, LA; ⁴Pathology, Ochsner Clinic Foundation, New Orleans, LA
Purpose:This study assesses imaging response characteristics of patients with hepatocellular carcinoma (HCC) to chemoembolization (TACE) as a bridge to transplant and the risk of post-transplant…
2017 American Transplant Congress
The Incidence, Mortality and Prediction Model for Fractures After Kidney Transplantation in the United States.
X. Liu, S. Bae, M. McAdams DeMarco, D. Segev.
JHU, Baltimore, MD
Kidney transplant (KT) recipients are more likely than general population to have fractures. In the general population, fractures are associated with morbidity, mortality, and high…
2017 American Transplant Congress
Molecular Classifier of Antibody-Mediated Rejection Is a Better Predictor of Histologic Rejection Than a Corresponding Transcript Set and Is Further Improved When Combined with Classifiers of Rejection Syndromes.
K. Famulski, P. Halloran.
University of Alberta, Edmonton, AB, Canada
Molecular and histologic changes in graft rejection are not completely specific, often being induced by injuries and other diseases. We examined various methods for using…
2017 American Transplant Congress
The Performance of Four Tools for the Prediction of Potential for Organ Donation After Cardiac Death in Neurocritical Patients: A Prospective, Multicenter, Observational Study.
Z. Guo,¹ G. Xu,¹ P. Schroder,² M. Manyalich,³ X. He,¹ G. Chen.¹
¹Organ Transplant Center, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China; ²Department of Surgery, Duke University Medical Center, Durham; ³Transplant Procurement Management-Donation & Transplantation institute Foundation, Barcelona, Spain
Background Successful donation after circulatory death (DCD) requires identification of patients dieing within limited time after withdrawal of life-sustaining treatment (WLST). We aimed to compare…