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Articles tagged "Prediction models"

  • 2016 American Transplant Congress

    Utility of Six-Minute-Walk Distance in Predicting Lung Transplant Benefit in the Lung Allocation Score Era.

    S. Shah,1 D. Tumin,3 B. Whitson,2 A. Pope-Harman,1 S. Kirkby,1 A. Kilic,2 P. Lee,2 D. Hayes.1,3

    1Pulmonary and Critical Care, Ohio State University Wexner Medical Center, Columbus, OH; 2Division of Cardiac Surgery, Ohio State University Wexner Medical Center, Columbus, OH; 3Pediatrics, Ohio State University, Columbus, OH.

    Transplant physicians evaluate patients for lung transplant (LTx) who are on ventilators and ECMO with high lung allocation scores (LAS). Six-minute walk distance (6MWD) predicts…
  • 2016 American Transplant Congress

    Three-Year Graft Loss Risk in Kidney Transplants: Dynamic Patient Level Data Improve Predictive Efficacy.

    T. Srinivas, J. Zhang, Z. Su, D. Taber, J. Marsden, K. Reilly, D. Northrup, J. Long, L. Lenert, W. Moran, P. Mauldin.

    MUSC, Charleston, SC.

    Background: Predictive models in kidney transplantation using national data (UNOS, SRTR) lack longitudinal patient level data, limiting accuracy. Adding patient level data capturing dynamic clinical…
  • 2016 American Transplant Congress

    Composite Score to Define the Risk of Allograft Loss After Standard-of-Care Treatment of Antibody-Mediated Rejection in Kidney Transplantation.

    D. Viglietti,1 A. Loupy,2 J. Duong Van Huyen,2 J. Verine,1 A. Zeevi,3 C. Legendre,2 D. Glotz,1 C. Lefaucheur.1

    1Saint-Louis Hospital, Paris, France; 2Necker Hospital, Paris, France; 3University of Pittsburgh Medical Center, Pittsburgh.

    The development of a reliable surrogate endpoint for allograft survival after AMR treatment is a current unmet need in clinical transplantation (FDA AMR Workshop). We…
  • 2016 American Transplant Congress

    Cytokine Networks in Kidney Transplant Patients.

    R. Sabat,1 E. Witte,1 P. Reinke,2 K. Wolk,1 N. Babel.3,4

    1Interdisciplinary Group Molecular Immunopathology, and Psoriasis Research and Treatment Center, Dermatology/Medical Immunology, Charite University Medicine Berlin, Berlin, Germany; 2Department of Nephrology and Berlin-Brandenburg Center for Regenerative Therapies, Charite University Medicine Berlin, Berlin, Germany; 3Medical Clinic I, Marien Hospital Herne, University Clinic Ruhr-University Bochum, Herne, Germany; 4Berlin-Brandenburg Center for Regenerative Therapies, Charite University Medicine Berlin, Berlin, Germany.

    As key mediators of the intercellular communication, cytokines play a crucial role in many processes following transplantation, including inflammation, tissue regeneration, and anti-microbial defense. Locally…
  • 2016 American Transplant Congress

    One-Year Graft Loss Risk in Kidney Transplants – A Big Data Approach.

    T. Srinivas, D. Taber, J. Zhang, Z. Su, J. Marsden, A. Tripathi, W. Moran, P. Mauldin.

    MUSC, Charleston, SC; IBM Corp., Armonk.

    Background Predictive models using national data are limited by lack of evolving patient level data. A Big Data approach using both static and dynamic variables…
  • 2016 American Transplant Congress

    Renal Risk Index and Acute Kidney Injury in Liver Transplant Patients.

    J. Neal, Y. Sun, J. Erley, J. Shen, C. Sonnenday, P. Sharma, J. Park.

    University of Michigan, Ann Arbor, MI.

    Purpose: Renal risk index (RRI) has been validated in liver transplant (LT) to predict post-transplant ESRD. We examined the clinical utility of RRI as a…
  • 2016 American Transplant Congress

    Probability of Transplant (POT) Index: A Novel Method to Predict the Likelihood of an Adult Liver Transplant.

    J. Moffett,1 M. Kueht,1 H. Petrowsky,2 I. Riaz,3 C. Nalty,4 S. Khaderi,1 C. O'Mahony,1 J. Goss,1 A. Rana.1

    1Division of Abdominal Transplantation, Baylor College of Medicine, Houston, TX; 2Department of Visceral and Transplant Surgery, University Hospital of Zurich, Zurich, Switzerland; 3Department of Internal Medicine, University of Arizona, Tucson, AZ; 4Department of Epidemiology and Biostatistics, Texas A&M Health Sciences Center, College Station, TX.

    Background: Access to liver transplantation is limited by a multitude of factors, which are quite variable among transplant candidates, and is underscored by the shortage…
  • 2016 American Transplant Congress

    A Call for a New Paradigm of Organ Allocation within the Confines of MELD for Those Who Are Not “the Sickest”.

    T. Baker, A. Siarris, P. Accoh, D. Ladner.

    Comprehensive Transplant Center, Northwestern University, Chicago, IL.

    BACKGROUND: Liver Allocation policy in the United States is in dynamic flux, with revisions in policy reflecting designs to optimize access to and outcomes for…
  • 2016 American Transplant Congress

    Characteristics and Outcome of Patients Placed on Extracorporeal Membrane Oxygenation as Bridge to Lung Transplantation.

    E. Batchelor, J. Bland, D. Douglass, J. Mullins, M. Mohanka, S. Bollineni, V. Kaza, M. Wait, F. Torres, A. Banga.

    University of Texas Southwestern Medical Center, Dallas, TX.

    BackgroundExtracorporeal membrane oxygenation (ECMO) is increasingly utilized as bridge to lung transplantation (LT), with studies reporting one-year survival of 50-90%. Lower than expected survival has…
  • 2016 American Transplant Congress

    Understanding the Dynamics of a Suddenly Plateauing Kidney Waiting List.

    A. Wilk, D. Stewart, E. Edwards.

    United Network for Organ Sharing, Richmond, VA.

    Background: The number of candidates on the kidney (KI) wait list (WL) abruptly flattened around the time the new Kidney Allocation System (KAS) was implemented…
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