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American Transplant Congress abstracts

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Articles tagged "Prediction models"

  • 2019 American Transplant Congress

    A Prognostic Biomarker to Estimate the Likelihood of Developing De Novo Donor Specific Antibody in Kidney Transplant Recipients

    S. Kawakita1, L. M. Rebellato2, K. P. Briley2, A. Q. Maldonado3, C. E. Haisch2, P. Bolin2, S. A. Kendrick4, H. Jones4, K. McLawhorn4, D. Leeser2, V. Jucaud1, V. Burnett1, M. J. Everly1

    1Terasaki Research Institute, Los Angeles, CA, 2East Carolina University, Greenville, NC, 3Vidant Medical Center, Greenville, NC, 4Eastern Nephrology Associates, Greenville, NC

    *Purpose: Evaluation of human leukocyte antigen (HLA) mismatch at antibody epitope level rather than antigen level may explain better the impact of HLA mismatch on…
  • 2019 American Transplant Congress

    A Collaborative AI Framework to Improve the MELD Exception Request Policy Process

    A. M. Placona, S. M. Noreen, R. Carrico

    Research, United Network for Organ Sharing, Henrico, VA

    *Purpose: A goal of organ allocation policy is to balance medical urgency with equitable access to transplant. MELD Exceptions attempt to ensure that patients’ medical…
  • 2019 American Transplant Congress

    A Prognostic Model to Identify Deceased Donor Kidney Transplant Recipients at High Risk for Delayed Graft Function

    S. Kawakita, J. L. Beaumont, M. J. Everly

    Terasaki Research Institute, Los Angeles, CA

    *Purpose: We have previously identified pre-transplant risk factors for delayed graft function (DGF) in deceased donor kidney transplant (DDKT) recipients and built a machine learning…
  • 2019 American Transplant Congress

    Change in Estimated Glomerular Filtration Rate and Risk of Allograft Failure in Patients Diagnosed with Active Antibody-Mediated Rejection Following Kidney Transplantation

    W. Irish1, P. Nickerson2, B. Astor3, E. Chong4, C. Wiebe2, F. Moreso5, D. Seron5, M. Crespo5, L. Gache6, A. Djamali3

    1East Carolina University, Greenville, NC, 2University of Manitoba, Winnipeg, MB, Canada, 3University of Wisconsin, Madison, WI, 4Vitaeris, Inc, Vancouver, BC, Canada, 5University Hospital Vall d'Hebron, Barcelona, Spain, 6CTI Clinical Trial & Consulting, Covington, KY

    *Purpose: There are challenges in designing an adequate and well-controlled study of patients with active antibody-mediated rejection (ABMR), especially in the absence of a valid…
  • 2019 American Transplant Congress

    Predicting Kidney Discards with Donor Admission Text

    A. Placona, C. Martinez, B. Carrico

    United Network for Organ Sharing, Richmond, VA

    *Purpose: Kidney discard rates have increased in part due to technological advancements and deceased donor policy updates that allow for recovery of organs at increased…
  • 2019 American Transplant Congress

    Risk Stratification of Patients Undergoing Simultaneous Liver Transplantation and Cardiac Surgery

    T. Diago Uso, G. D'Amico, S. Armanyous, L. Lomaglio, B. Eghtesad, M. Fujiki, F. Aucejo, K. Sasaki, N. K. Menon, M. Fares, M. Tong, K. Hashimoto, C. Miller, C. Quintini

    Cleveland Clinic, Cleveland, OH

    *Purpose: Evaluate risk factors and outcomes of combined liver transplantation (OLT) and cardiac surgery, including coronary artery grafting and valve replacement.*Methods: Between 1/2005 and 8/2018,…
  • 2019 American Transplant Congress

    More Than Meets the Eye: The Use of Serial Intravascular Ultrasound for Assessment of Cardiac Allograft Vasculopathy after Heart Transplantation

    Y. Moayedi1, C. Fan2, M. Tremblay-Gravel1, R. J. Miller1, M. Kawana1, J. Parizo1, G. Oro1, R. Wainwright1, H. I. Luikart1, N. D'Emilio1, J. Gordon1, R. Kameda1, M. Ikutomi1, C. Manlhiot1, W. F. Fearon1, H. J. Ross1, K. K. Khush1, J. J. Teuteberg1

    1Stanford University, Palo Alto, CA, 2University of Toronto, Toronto, ON, Canada

    *Purpose: Cardiac allograft vasculopathy (CAV) is the “Achilles heel” of long-term survival after heart transplantation. While conventional coronary angiography is recognised as the standard for…
  • 2019 American Transplant Congress

    A Prognostic Drug Development Tool to Assess the Transplantability at the Time of Listing for Kidney Transplant Candidates

    S. Kawakita1, L. Hidalgo-Semlek2, J. L. Beaumont1, J. Lee2, M. J. Everly1

    1Terasaki Research Institute, Los Angeles, CA, 2Hansa Medical AB, Lund, Sweden

    *Purpose: At time of listing for kidney transplant (KT), a patient is not informed of the probabilities of KT, death, or remaining on the waiting…
  • 2019 American Transplant Congress

    External Validation of the Living Kidney Donor Profile Index (LKDPI) in the Canadian Kidney Transplant Recipient Population

    M. Shantier1, Y. Li1, M. Ashwin1, O. Famure1, S. K. Singh2

    1Multi-Organ Transplant Program, University Health Network, Toronto, ON, Canada, 2Department of Medicine, University of Toronto, Multi-Organ Transplant Program, University Health Network, Toronto, ON, Canada

    *Purpose: The LKDPI is a risk index which incorporates clinical characteristics of living kidney donors and their recipients to predict the risk of total graft…
  • 2019 American Transplant Congress

    Immunobiogram, a New IVD Immunoassay to Test the Sensitivity Profile of Kidney Transplant Recipients to Immunosuppressive Drugs: Further Results from BH-Pilot Study

    C. Jimenez1, J. M. Portoles2, D. Blánquez3, L. Arribas3, A. Ortega4, T. Diez5, I. Portero6

    1Nephrology Department, La Paz Hospital, Madrid, Spain, 2Nephrology Department, Puerta de Hierro Mahadahonda Hospital, Madrid, Spain, 3Adamas Engineering Consulting, Madrid, Spain, 4I+D, Biohope, Madrid, Spain, 5Medical, Biohope, Madrid, Spain, 6CEO, Biohope, Madrid, Spain

    *Purpose: IMBG is an immunoassay developed by Biohope to measure in vitro PBMC sensitivity/resistance profile to a panel of immunosuppressive drugs (IS) in Kidney Transplant…
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