Articles tagged "Post-transplant malignancy"

2017 American Transplant Congress
Genomic Diversity of Epstein-Barr Virus in Post-Transplant Lymphoproliferative Disorder.
E. Maloney, O. Martinez.
Program in Immunology, Stanford University School of Medicine, Stanford, CA
Purpose: In transplant recipients, Epstein-Barr Virus (EBV) is associated with the development of B cell lymphomas in post-transplant lymphoproliferative disorder (PTLD). We used next-generation sequencing…
2017 American Transplant Congress
Identification of Kidney Transplant Patients at Risk for Skin Cancer by Differentially Methylated Regions in T Cells.
F. Peters,¹ A. Peeters,¹ P. Mandaviya,² J. van de Wetering,¹ M. Betjes,¹ C. Baan,¹ K. Boer.¹
¹Nephrology and Transplantation, Erasmus MC, University Medical Center, Rotterdam, Netherlands; ²Clinical Chemistry, Erasmus MC, University Medical Center, Rotterdam, Netherlands
Skin cancer, specifically cutaneous squamous cell carcinoma (cSCC), is the most often occurring malignancy in patients after organ transplantation, with an incidence of 100-200 times…
2017 American Transplant Congress
Donor Derived and BK Virus Positive Urologic Cancers After Renal Transplantation.
V. Hellström,¹ G. Tufveson,¹ A. Wallgren,² A. Loskog,² E. Larsson,² T. Töttermann,² M. Bengtsson,² A. Laurell,² C. Lundberg,¹ B. Holmström,¹ G. Enblad,² T. Lorant.¹
¹Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; ²Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden
Background. Donor-derived tumours in organ recipients develop from donor tissue with no known pre-existing malignancy in the donor. In addition, polyoma BK virus (BKV) might…
2017 American Transplant Congress
BK Polyoma Virus and Malignancy: Cause or Co-Incidence?
R. Prashar, A. Shah, D. Stewart, S. Williamson, A. Patel.
Henry Ford Transplant Institute, Detroit, MI
BackgroundThe WHO agency for cancer research has classified BKV as "possibly carcinogenic".The etiological role of BKV in human cancer, however,remains controversial.We present 5 cases of…
2017 American Transplant Congress
Outcomes of Renal Disease Related to Monoclonal Gammopathy After Kidney Transplantation: A Single Center Experience.
T. Kaur, E. Poggio, S. Nurko.
Nephrology, Cleveland Clinic, Cleveland
Kidneys are commonly involved in patients with monoclonal gammopathies (MG). However, the role of kidney transplants (KTx) in MG still needs to be more clearly…
2017 American Transplant Congress
10 Years of DTAC Experience with Kaposi's Sarcoma – Not Just Another PTLD!
M. Nalesnik,¹ M. Clark,² S. Tlusty,² M. Michaels,¹ C. Wolfe.¹
¹DTAC, Richmond; ²United Network for Organ Sharing, Richmond
Background:Kaposi's Sarcoma (KS), a tumor derived from the oncogenic virus human herpesvirus-8 (HHV8) is strongly associated with immunodeficiencies. Classically seen with AIDS, it can also…
2016 American Transplant Congress
The First 48 Months of an Australian Renal and Liver Organ Transplant Dermatology Database.
L. Ge,^1,2 P. Lowe.^1,2
¹Department of Dermatology, Royal Prince Alfred Hospital, Sydney, NSW, Australia; ²Faculty of Medicine, University of Sydney, Sydney, NSW, Australia.
PurposeThere have been few studies of non-melanoma skin cancers in the Australian cohort, a population unique for its high ambient UV radiation and sun-long lifestyle.…
2016 American Transplant Congress
An Epidemiological Update of Non-Melanoma Skin Cancer in Immunosuppressed Organ Transplant Recipients with Skin of Color.
C. Shaver, C. Cusack, C. Chung.
Dermatology, Drexel University College of Medicine, Philadelphia, PA.
Introduction:It is predicted by the US census that by year 2050, minorities will become the majority US population. We know skin cancer in patients with…
2016 American Transplant Congress
Thorough Pre-Transplant Evaluation and Appropriate Case Selection Is the Mainstay for Better Survival in Recipients with Malignancy.
W. Yin.^1,2
¹Surgery, School of Medicine, Tzu Chi University, Hualien, Taiwan; ²Surgery, Dalin Tzu Chi General Hospital, Chia-I, Taiwan.
IntroductionMalignancy has become one of the three major causes of death after transplantation in the past decade and is thus increasingly important in all organ…
2016 American Transplant Congress
Prostate Cancer Characteristics and Outcome in Renal Transplant Recipients: Results from a Contemporary Monocentric Study.
C. Pettenati,¹ A.-S. Jannot,² V. Verkarre,³ S. Hurel,¹ H. Kreis,⁴ M. Housset,⁵ C. Legendre,⁴ A. Méjean,¹ M.-O. Timsit.¹
¹Department of Urology and Transplant surgery, Hôpital Européen Georges Pompidou, AP-HP, Université Paris Descartes, Paris, France; ²Department of Statistics, Computing and Public Health, Hôpital Européen Georges Pompidou, AP-HP, Université Paris Descartes, Paris, France; ³Department of Pathology, Hôpital Necker, AP-HP, Université Paris Descartes, Paris, France; ⁴Department of Nephrology and Transplantation, Hôpital Necker, AP-HP, Université Paris Descartes, Paris, France; ⁵Department of Onco-Radiotherapy, Hôpital Necker, AP-HP, Université Paris Descartes, Paris, France.
Objective To analyze prostate cancer characteristics in a contemporary monocentric renal transplant recipients (RTR) population and to compare oncological outcome after radical prostatectomy (RP) with…