ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Post-transplant lymphoproliferative disorder (PTLD)"

  • 2020 American Transplant Congress

    Role of CAR-T Cell Therapy in Post Transplant Lymphoproliferative Disorder

    S. Krishnamoorthy, A. Malone, R. Delos Santos, H. Murad, T. Alhamad

    Transplant, Washington University in St. Louis, Saint Louis, MO

    *Purpose: Chimeric Antigen Receptor (CAR) T cells are a genetically modified autologous immunotherapy that uses a patient’s own T cells modified with a chimeric antigen…
  • 2020 American Transplant Congress

    Malignancy Incidence after Pediatric Kidney Transplantation; a Single-Center Experience in Japan

    Y. Aoki1, H. Satoh1, R. Hamada2, R. Harada2, M. Muramatsu3, Y. Hamasaki3, S. Shishido3

    1Urology and Kidney Transplantation, Tokyo Metropolitan Children’s Medical Center, Tokyo, Japan, 2Nephrology, Tokyo Metropolitan Children’s Medical Center, Tokyo, Japan, 3Nephrology, Toho University, Faculty of Medicine, Tokyo, Japan

    *Purpose: The incidence of malignancy was higher in organ transplant recipients than in the general population, and malignancies are a well-recognized complication of organ transplantation.…
  • 2020 American Transplant Congress

    Incidence of Skin Cancer – A Long Term Outcome of Immunosuppression in Renal Transplant Recipients Associated with the Usage of Azathioprine

    H. Bheemreddy1, S. Yusuf1, N. Krishnan2, A. Imtiaz3

    1Health and Life Sciences, Coventry University, Coventry, United Kingdom, 2Renal Unit, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom, 3Department of Dermatology, University Hospital Coventry and Warwickshire NHS Trust, Coventry, United Kingdom

    *Purpose: The main cause of mortality in Kidney Transplant Recipient’s (KTRs) is malignancy. The cancer incidence is increased by treating with immunosuppressive agents and longer…
  • 2020 American Transplant Congress

    Impact of Immunosuppression Protocol on the Incidence of EBV Viremia and PTLD in Pediatric Kidney Transplant Recipients: A Single Center Experience

    K. Bowers1, V. M. Panzarino1, A. Campos1, J. Buggs2, V. D. Bowers2

    1Pediatrics, USF, Tampa, FL, 2Transplant Surgery, TGH, Tampa, FL

    *Purpose: The purpose of this study was to evaluate the efficacy of an immunosuppression protocol change, which included avoidance of anti-thymocyte globulin for induction and…
  • 2020 American Transplant Congress

    Causal Relationship between Anti-Thymocyte Globulin Induction Therapy and Development of Monomorphic PTLD in Renal Transplant Recipients

    K. Soliman1, H. Ali2, T. Fulop1, A. Osman3, A. Halawa4

    1Medicine, Medical University of South Carolina, Charleston, SC, 2Medicine, Royal Stoke, Royal Stoke, United Kingdom, 3Medicine, Cairo University, Cairo, Egypt, 4Medicine, University of Liverpool, Liverpool, United Kingdom

    *Purpose: The aim of our study is to explore the causality between ATG and different types of post-transplant lymphoproliferative disorder (PTLD) in renal transplant recipients…
  • 2020 American Transplant Congress

    Sequence Variations of the LMP1 Protein are Detected in Pediatric Transplant Recipients and May Increase the Risk of EBV Disease

    B. Mbiribindi1, M. Arvedson1, J. Pena1, O. Hatton2, C. Esquivel1, O. Martinez1, S. Krams1

    1Department of Surgery/Division of Abdominal Transplantation, Stanford Univ School of Med, Stanford, CA, 2Molecular Biology, Colorado College, Colorado Springs, CO

    *Purpose: Epstein-Barr virus (EBV) infects more than 90% of adults worldwide and is associated with several malignancies, including post-transplant lymphoproliferative disorder (PTLD). PTLD is a…
  • 2019 American Transplant Congress

    Epstein Barr Virus DNA Integration in B Cell Lymphomas of Post-Transplant Lymphoproliferative Disorder

    M. C. McPherson, O. M. Martinez

    Surgery, Division of Abdominal Transplant, Stanford University School of Medicine, Stanford, CA

    *Purpose: Epstein Barr virus-positive (EBV+) B cell lymphomas can arise in immunosuppressed individuals, such as organ transplant recipients in the context of post-transplant lymphoproliferative disorder…
  • 2019 American Transplant Congress

    Post-transplant Lymphoproliferative Disorder Following Intestine Transplantation: Contemporary Single Center Experience

    A. Zimmerman, J. Hawksworth, A. Kroemer, P. Radkani, K. Khan, S. Kaufman, N. Yazigi, S. Subramanian, T. Fishbein, C. Matsumoto

    Georgetown Transplant Institute, MedStar Georgetown University Hospital, Washington, DC

    *Purpose: The purpose of this study was to examine the characteristics and risk factors for PTLD after intestinal transplant.*Methods: Retrospective review of intestinal transplant recipients…
  • 2019 American Transplant Congress

    EBV+ PTLD in the Modern Immunosuppression Era: Role of EBV Serology and DNAemia-Preliminary Data from CTOT-C06

    O. M. Martinez1, S. M. Krams1, M. A. Robien2, M. Lapasaran1, S. D. Boyd1, B. Armstrong3, C. Twist4, K. Weinberg1, D. Gratzinger1, B. Tan1, M. Sever3, D. Ikle3, M. Brown2, D. Bernstein1, C. O. Esquivel1

    1Stanford University Sch of Med, Stanford, CA, 2NIAID/NIH, Rockville, MD, 3Rho, Chapel Hill, NC, 4Roswell Park, Buffalo, NY

    *Purpose: Post-transplant lymphoproliferative disorder (PTLD) remains a serious problem in the pediatric transplant population. The Clinical Trials of Organ Transplantation in Children (CTOT-C)-06 is an…
  • 2019 American Transplant Congress

    Lower Rates of Epstein-Barr Virus Viremia and Post-Transplant Lymphoproliferative Disease in Pediatric Solid Organ Transplant Recipients Who Received Valganciclovir Prophylaxis

    E. A. Moulton1, M. Karandikar2, S. Bond3, S. Burchett2, T. Sharma2, F. M. Marty3

    1Baylor College of Medicine, Houston, TX, 2Boston Children's Hospital, Boston, MA, 3Brigham and Women's Hospital, Boston, MA

    *Purpose: Antiviral prophylaxis to prevent post-transplant lymphoproliferative disease (PTLD) remains controversial, but some data suggest that valganciclovir or ganciclovir use in Epstein-Barr virus (EBV) high-risk…
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