2019 American Transplant Congress
Tacrolimus Activated BMP Signaling Acts in Synergy with Stress-Activated FOXO1 to Induce Loss of Beta-Cell Function and Identity
*Purpose: Tacrolimus, the most widely used immunosuppressive drug, is known to be highly diabetogenic. It is thought to trigger β-cell death through inhibition of the…2019 American Transplant Congress
Successful Kidney Transplant Improves Glucose Tolerance – A Paradoxical Report From A Single Center
Kidney Transplantation Surgery, Sapporo City General Hospital, Sapporo, Japan
*Purpose: Kidney recipients tend to impair glucose tolerance because of several factors such as post-operative obesity, and chronic exposure of some diabetogenic immunosuppressants like calcineurin…2019 American Transplant Congress
Insulin Resistance as a Surrogate Marker for Post-Transplantation Diabetes Mellitus
Department of Medicine, Division of Nephrology, Federal University of São Paulo, São Paulo, Brazil
*Purpose: Post-transplantation diabetes mellitus (PTDM) adversely impact patient and kidney allograft survival. Further knowledge of the risk factors involved in the onset and progression of…2019 American Transplant Congress
New-Onset Diabetes after Kidney Transplantation: Risk Factors and Early Graft Function Outcome
Kidney Disease Center, First Affiliated Hospital of Zhejiang University, Hangzhou, China
*Purpose: New-onset of diabetes mellitus after transplantation (NODAT) is a serious and common complication following solid organ transplantation. Our study aims to examine the risk…2019 American Transplant Congress
The Need for Diabetic Medications after Pancreas Transplantation
Mount Sinai Hospital, New York, NY
*Purpose: Patients with diabetes mellitus can experience microvascular complications resulting in end organ damage ultimately necessitating pancreatic transplantation. While there is well documented improvement in…2019 American Transplant Congress
FK506 Influence Glucose Metabolism by Short Chain Fatty Acid
*Purpose: FK506 is one of the most common immunosuppressant drugs in organ transplantation, which have been demonstrated to cause glucose metabolism disorder and alterd the…2019 American Transplant Congress
Impact of Steroid-Free Protocol on Incidence of Posttransplantation Diabetes Mellitus: A Prospective, Randomized, Multicenter, Open-Label, Controlled Trial in Renal Transplant Recipients
*Purpose: Comparison of two immunosuppressive protocols, steroid-free with antithymocyte globulin (ATG) induction, and steroid containing with basiliximab induction, regarding the incidence of PTDM, one year…2019 American Transplant Congress
Efficacy and Safety with Empagliflozin in Renal Transplant Recipients with Post-Transplant Diabetes Mellitus
*Purpose: Post-transplant diabetes mellitus (PTDM) is a highly prevalent condition following renal transplantation, associated with increased risk of cardiovascular disease and impaired patient survival. Sodium-glucose…2019 American Transplant Congress
Belatacept Based Simultaneous Calcineurin Inhibitor Avoidance/Early Corticosteroid Withdrawal is Associated with Low New Onset Diabetes Risk
*Purpose: Calcineurin inhibitor (CNI) and/or corticosteroid (CCS) therapy are associated with significant risk of new onset diabetes after transplantation (NODAT). An important consideration for simultaneous…2019 American Transplant Congress
Comparison of Two Glucagon-Like-Peptide-1 Analogs (GLP -1) Dulaglutide vs Liraglutide for the Management of Diabetes in Solid Organ Transplant (SOT)
Ohio State University, Columbus, OH
*Purpose: Poorly controlled Type-2 diabetes is an important contributor to graft dysfunction, and cardiovascular morbidity in the SOT. GLP-1-analog has been widely used in the…
American Transplant Congress abstracts