2021 American Transplant Congress
Duration and Magnitude of BK Viremia Do Not Predict Outcome in Patients After Kidney Transplantation
*Purpose: BK viremia was a major cause of kidney transplant failure in the early 2000’s and remains a risk factor for subsequent rejection. The standard…2021 American Transplant Congress
Donor-Derived Cell-Free DNA Levels Risk-Stratify Polyoma BK Viremia and Associated Clinical Events After Kidney Transplantation – Preliminary Results from ADMIRAL Study
*Purpose: The threshold of 10,000 copies for blood Quant BK PCR has been used as a surrogate for BK nephropathy (BKN) in kidney transplant recipients…2021 American Transplant Congress
Transcriptomics and Proteomics Profiling of Complement Pathway (cp) Proteins in Biopsies With Polyomavirus Bk Nephropathy (bkvn)
*Purpose: Late stage BKVN can show C4d as well as classic immune complex deposits in the tubular basement membranes (Bracamonte et al. Am J Transplant…2020 American Transplant Congress
Incidence and Risks Factors of Kidney Allograft Loss Due to BK Virus in Pediatric Population: UNOS Data Set
*Purpose: BK virus infection can lead to graft dysfunction and loss in kidney transplant patients. Incidence and prevalence of BK Viremia (BKV) and BK Virus…2020 American Transplant Congress
Risk Factors for BK Virus Infection after Kidney Transplantation in the Contemporary Era: A Single-Centre Observational Study
*Purpose: BK infection remains a risk factor for kidney transplant dysfunction and allograft loss. While many risk factors are reported in the literature, many are…2020 American Transplant Congress
Development of Self-Limited Low-Level BK Viremia/Viruria Suggests Ideal Immunosuppression to Suppress T-Cell and Antibody-Mediated Rejection and to Preserve Kidney Allograft Function
University Hospital Zurich, Zurich, Switzerland
*Purpose: Polyomavirus BK (BKV) has been suggested as a surrogate marker of overimmunosuppression. Due to recent advances in monitoring strategies and pre-emptive therapy, progression to…2020 American Transplant Congress
Everolimus for BKV Nephropathy in Kidney Transplant Recipients: A Prospective, Controlled Study
*Purpose: Polyoma BK virus nephropathy (BKVN) of KTRs is associated with adverse outcome, since no specific therapy exists. EVR showed promising antiviral effects but systematic…2020 American Transplant Congress
The Noninvasive Urinary Sediment Double Immunostaining Test Predicts BK Polyomavirus Nephropathy in Kidney Transplant Recipients
*Purpose: This study aimed to improve the diagnostic value of decoy cells for BK polyomavirus associated-nephropathy (BKPyVAN) in kidney transplant recipients.*Methods: A total of 105…2020 American Transplant Congress
Impact of Depleting Induction Agents on BK Virus and Polyomavirus Associated Nephropathy
*Purpose: Polyomavirus associated nephropathy (PVAN) is an opportunistic infection associated with graft loss and rejection. Due to limited treatment options, identifying kidney transplant recipients at…2020 American Transplant Congress
Longitudinal Study Investigating Characteristics of Human Polyimaviruses Infection after Kidney Transplantation
*Purpose: Human Polyomaviruses (HPyV) infections are extremely common, ranging from 60% to 100% in the general population, depending on the virus. After primary infection, which…
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