Articles tagged "Polyma virus"

2021 American Transplant Congress
BKV-Associated Urothelial Carcinoma in Patients After Renal and Extrarenal Carcinoma
A. Schwarz¹, J. Schmitz², J. Gottlieb³, C. Bara⁴, H. Haller¹, J. Braesen²
¹Nephrology Department, Hannover Medical School, Hannover, Germany, ²Institute of Pathology, Hannover Medical School, Hannover, Germany, ³Department of Pneumology, Hannover Medical School, Hannover, Germany, ⁴Department of Thoracic Surgery, Hannover Medical School, Hannover, Germany
*Purpose: Polyomavirus BK (BKV) reactivation or transmission is a wellknown problem in renal transplant (TX) patients with BKV nephropathy and interstitial cystitis. The role of…
2021 American Transplant Congress
Polyomavirus BK-Associated Nephropathy in Patients After Renal and Extrarenal Transplantation
A. Schwarz¹, J. Schmitz², J. Braesen², C. Bara³, M. Sauer⁴, H. Haller¹, J. Gottlieb⁵
¹Nephrology Department, Hannover Medical School, Hannover, Germany, ²Institute of Pathology, Hannover Medical School, Hannover, Germany, ³Department of Thoracic Surgery, Hannover Medical School, Hannover, Germany, ⁴Department of Pediatric Hematology, Hannover Medical School, Hannover, Germany, ⁵Deparment of Pneumology, Hannover Medical School, Hannover, Germany
*Purpose: Patients with non-renal organ transplantation (TX) may suffer BK-viral nephropathy (BKVN) of their own orthotopic kidneys. We aimed to know if these patients with…
2021 American Transplant Congress
Conversion from Tacrolimus to Envarsus in Rapid Metabolizers for Prevention of BK Infection
G. Towns, G. Agarwal, C. Kew
Transplant Nephrology, UAB, Birmingham, AL
*Purpose: The incidence of BK virus infection is high among rapid metabolizers (RM) in kidney transplant (KT) patients. RM can be identified using validated and…
2020 American Transplant Congress
A Prospective Randomized Multicenter Trial (BEST Trial) of Belatacept-Based CNI- and Corticosteroid-Free Immunosuppression: Infectious Complications
P. West-Thielke¹, A. Shields², D. Kaufman³, J. Leone⁴, A. Wiseman⁵, A. Matas⁶, T. Sa⁷, E. King⁷, R. Alloway², S. Woodle²
¹University of Illinois, Chicago, IL, ²University of Cincinnati, Cincinnati, OH, ³University of Wisconsin, Madison, IL, ⁴Tampa General Hospital, Tampa, FL, ⁵University of Colorado, Aurora, CO, ⁶University of Minnesota, Minneapolis, MN, ⁷Cincinnati Children's Hospital Medical Center, Cincinnati, OH
*Purpose: The BEST Trial (Belatacept-based Early Steroid Withdrawal Trial) is a prospective, randomized, multi-center trial designed to compare two belatacept (BELA)-based calcineurin inhibitor-free (CNI), early…
2020 American Transplant Congress
Urinary CXCL10: From Diagnosis to Prediction of BK Viremia in Kidney Transplantation
C. Tinel¹, A. Vermorel¹, D. Picciotto¹, L. Morin¹, C. Legendre¹, M. Rabant², D. Anglicheau¹
¹Kidney Transplantation, Inserm U1151, Necker Hospital, Paris, France, ²Pathology, Necker Hospital, Paris, France
*Purpose: Urinary CXCL10 (uCXCL10) has proved to be a useful tool for the non-invasive diagnosis of acute rejection in kidney transplant recipients (KTRs). Upon development,…
2020 American Transplant Congress
Valganciclovir Prophylaxis is Not Associated with Polyomavirus Viremia after Renal Transplantation
D. Conti¹, D. Schuster¹, M. Garner¹, E. Maciera¹, S. Patel²
¹Albany Medical Center, Albany, NY, ²Surgery, Albany Medical Center, Albany, NY
*Purpose: Recent studies have implicated prophylactic valganciclovir (VGC) therapy after renal transplantation to be associated with an increased rate of BK polyomavirus viremia and nephropathy.…
2020 American Transplant Congress
Comparative Analysis of Risks Factors for Kidney Allograft Loss Due to Bk Nephropathy and Graft Loss Due to Other Causes: UNOS Data Set
H. Patel¹, L. Kruger¹, K. Agarwal¹, A. Pawar¹, N. Leeaphorn², F. Cardarelli¹, N. Agrawal¹
¹Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, ²Transplant Nephrology, University of Missouri-Kansas City School of Medicine/Saint Luke's Health System, Kansas City, MO
*Purpose: 1-10% of the kidney transplant recipients develop BK virus nephropathy (BKVN). The risk factors associated with BKVN are not clearly understood. Here, we evaluate…
2020 American Transplant Congress
The Importance of Caveolin-1 Immunohistochemical Staining for BK Nephropathy Seen after Kidney Transplantation
E. Arpali¹, E. Sunnetcioglu², Y. Özlük², A. Turkmen³, F. S. Oğuz¹
¹Medical Biology, Istanbul University School of Medicine, Istanbul, Turkey, ²Pathology, Istanbul University School of Medicine, Istanbul, Turkey, ³Nephrology, Istanbul University School of Medicine, Istanbul, Turkey
*Purpose: To understand the importance of molecular expression of Caveolin-1 in BKV nephropathy seen after kidney transplantion.*Methods: The kidney transplant patients who had a graft…
2020 American Transplant Congress
Polyoma Virus Infection in Renal Transplant Recipients Using Tacrolimo and Everolimo
P. M. Souza¹, C. Ribeiro¹, S. C. Miranda¹, A. S. Alvarenga¹, C. R. Felipe¹, G. Marques¹, G. P. Tarcia¹, L. L. Braga², L. S. Ferreira Boy², M. L. Martins²
¹Nephrology, Santa Casa de Belo Horizonte, Belo Horizonte, Brazil, ²Scientific Technical Development Management, Hemominas Foundation, Belo Horizonte, Brazil
*Purpose: Seropositivity for polyoma virus can reach 80% in kidney transplant recipients, with 1 to 10% polyoma associated nephropathy which negatively influences graft survival. Therefore,…
2020 American Transplant Congress
Maintenance Belatacept Therapy is Associated with Increased Rates of Polyoma Viremia
D. Conti, E. Maciera, D. Pluckrose, M. Garner, D. Schuster, S. Patel
Albany Medical Center, Albany, NY
*Purpose: The introduction of belatacept costimulatory blockade therapy has added a novel and powerful agent to the immunosuppressive armamentarium utilized after renal transplantation. However, limited…

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